High gene expression of inflammatory markers and IL-17A correlates with severity of injection site reactions of Atlantic salmon vaccinated with oil-adjuvanted vaccines

• Published in: BMC Genomics
• Main Authors: Koop Ben F, Marjara Inderjit S, Cooper Glenn A, Mutoloki Stephen, Evensen Øystein
• Format: Article in Journal/Newspaper
• Language: English
• Published: BMC 2010
• Subjects: Biotechnology; TP248.13-248.65; Genetics; QH426-470; Gata; Atlantic salmon
• Online Access: https://doi.org/10.1186/1471-2164-11-336; https://doaj.org/article/1b7605218e70411db24635d843eda306

Abstract Background Two decades after the introduction of oil-based vaccines in the control of bacterial and viral diseases in farmed salmonids, the mechanisms of induced side effects manifested as intra-abdominal granulomas remain unresolved. Side effects have been associated with generation of aut...