SARS-CoV-2 reinfection caused by the P.1 lineage in Araraquara city, Sao Paulo State, Brazil

• Published in: Revista do Instituto de Medicina Tropical de São Paulo
• Main Authors: Camila Malta Romano, Alvina Clara Felix, Anderson Vicente de Paula, Jaqueline Góes de Jesus, Pamela S. Andrade, Darlan Cândido, Franciane M. de Oliveira, Andreia C. Ribeiro, Francini C. da Silva, Marta Inemami, Angela Aparecida Costa, Cibele O. D. Leal, Walter Manso Figueiredo, Claudio Sergio Pannuti, William M. de Souza, Nuno Rodrigues Faria, Ester Cerdeira Sabino
• Format: Article in Journal/Newspaper
• Language: English
• Published: Universidade de São Paulo (USP) 2021
• Subjects: SARS-CoV-2; COVID-19; Reinfection; Variants of concern; P.1 lineage; Arctic medicine. Tropical medicine; RC955-962; Infectious and parasitic diseases; RC109-216; Arctic
• Online Access: https://doi.org/10.1590/s1678-9946202163036; https://doaj.org/article/1b62942006d84de5ae9868af59981908

ABSTRACT Reinfection by the severe acute respiratory syndrome coronavirus type 2 (SARS-COV-2) has been reported in many countries, suggesting that the virus may continue to circulate among humans despite the possibility of local herd immunity due to massive previous infections. The emergence of variants of concern (VOC) that are more transmissible than the previous circulating ones has raised particular concerns on the vaccines effectiveness and reinfection rates. The P.1 lineage was first identified in December 2020 in Manaus city and is now globally spread. We report the first case of reinfection of SARS-CoV-2 caused by the P.1 variant outside of Manaus. The potential of these new variants to escape naturally and vaccine- induced immunity highlights the need for a global vigilance.