Interdisciplinary researches for potential developments of drugs and natural products
Developments of drugs or natural products from plants are possibly made, simple to use and lower cost than modern drugs. The development processes can be started with studying local wisdom and literature reviews to choose the plants which have long been used in diverse areas, such as foods, traditio...
Published in: | Asian Pacific Journal of Tropical Biomedicine |
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Wolters Kluwer Medknow Publications
2017
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Online Access: | https://doi.org/10.1016/j.apjtb.2016.12.019 https://doaj.org/article/1ae602d051114cac9d0f521a0264b7a4 |
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ftdoajarticles:oai:doaj.org/article:1ae602d051114cac9d0f521a0264b7a4 2023-05-15T15:06:38+02:00 Interdisciplinary researches for potential developments of drugs and natural products Arunrat Chaveerach Runglawan Sudmoon Tawatchai Tanee 2017-04-01T00:00:00Z https://doi.org/10.1016/j.apjtb.2016.12.019 https://doaj.org/article/1ae602d051114cac9d0f521a0264b7a4 EN eng Wolters Kluwer Medknow Publications http://www.sciencedirect.com/science/article/pii/S2221169117300370 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/j.apjtb.2016.12.019 https://doaj.org/article/1ae602d051114cac9d0f521a0264b7a4 Asian Pacific Journal of Tropical Biomedicine, Vol 7, Iss 4, Pp 378-384 (2017) Cell viability Comet assay Drug development GC–MS Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 article 2017 ftdoajarticles https://doi.org/10.1016/j.apjtb.2016.12.019 2022-12-31T14:31:04Z Developments of drugs or natural products from plants are possibly made, simple to use and lower cost than modern drugs. The development processes can be started with studying local wisdom and literature reviews to choose the plants which have long been used in diverse areas, such as foods, traditional medicine, fragrances and seasonings. Then those data will be associated with scientific researches, namely plant collection and identification, phytochemical screening by gas chromatography-mass spectrometry, pharmacological study/review for their functions, and finally safety and efficiency tests in human. For safety testing, in vitro cell toxicity by cell viability assessment and in vitro testing of DNA breaks by the comet assay in human peripheral blood mononuclear cells can be performed. When active chemicals and functions containing plants were chosen with safety and efficacy for human uses, then, the potential medicinal natural products will be produced. Based on these procedures, the producing cost will be cheaper and the products can be evaluated for their clinical properties. Thus, the best and lowest-priced medicines and natural products can be distributed worldwide. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Asian Pacific Journal of Tropical Biomedicine 7 4 378 384 |
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Directory of Open Access Journals: DOAJ Articles |
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language |
English |
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Cell viability Comet assay Drug development GC–MS Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
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Cell viability Comet assay Drug development GC–MS Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 Arunrat Chaveerach Runglawan Sudmoon Tawatchai Tanee Interdisciplinary researches for potential developments of drugs and natural products |
topic_facet |
Cell viability Comet assay Drug development GC–MS Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
description |
Developments of drugs or natural products from plants are possibly made, simple to use and lower cost than modern drugs. The development processes can be started with studying local wisdom and literature reviews to choose the plants which have long been used in diverse areas, such as foods, traditional medicine, fragrances and seasonings. Then those data will be associated with scientific researches, namely plant collection and identification, phytochemical screening by gas chromatography-mass spectrometry, pharmacological study/review for their functions, and finally safety and efficiency tests in human. For safety testing, in vitro cell toxicity by cell viability assessment and in vitro testing of DNA breaks by the comet assay in human peripheral blood mononuclear cells can be performed. When active chemicals and functions containing plants were chosen with safety and efficacy for human uses, then, the potential medicinal natural products will be produced. Based on these procedures, the producing cost will be cheaper and the products can be evaluated for their clinical properties. Thus, the best and lowest-priced medicines and natural products can be distributed worldwide. |
format |
Article in Journal/Newspaper |
author |
Arunrat Chaveerach Runglawan Sudmoon Tawatchai Tanee |
author_facet |
Arunrat Chaveerach Runglawan Sudmoon Tawatchai Tanee |
author_sort |
Arunrat Chaveerach |
title |
Interdisciplinary researches for potential developments of drugs and natural products |
title_short |
Interdisciplinary researches for potential developments of drugs and natural products |
title_full |
Interdisciplinary researches for potential developments of drugs and natural products |
title_fullStr |
Interdisciplinary researches for potential developments of drugs and natural products |
title_full_unstemmed |
Interdisciplinary researches for potential developments of drugs and natural products |
title_sort |
interdisciplinary researches for potential developments of drugs and natural products |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2017 |
url |
https://doi.org/10.1016/j.apjtb.2016.12.019 https://doaj.org/article/1ae602d051114cac9d0f521a0264b7a4 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Asian Pacific Journal of Tropical Biomedicine, Vol 7, Iss 4, Pp 378-384 (2017) |
op_relation |
http://www.sciencedirect.com/science/article/pii/S2221169117300370 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/j.apjtb.2016.12.019 https://doaj.org/article/1ae602d051114cac9d0f521a0264b7a4 |
op_doi |
https://doi.org/10.1016/j.apjtb.2016.12.019 |
container_title |
Asian Pacific Journal of Tropical Biomedicine |
container_volume |
7 |
container_issue |
4 |
container_start_page |
378 |
op_container_end_page |
384 |
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