Antimicrobial Resistance of Enteric Salmonella in Bangui, Central African Republic
Introduction. The number of Salmonella isolated from clinical samples that are resistant to multiple antibiotics has increased worldwide. The aim of this study was to determine the prevalence of resistant Salmonella enterica isolated in Bangui. Methods. All enteric Salmonella strains isolated from p...
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ftdoajarticles:oai:doaj.org/article:1ac17fb3b2e84e82800b4b35fd94ffc7 2023-05-15T15:07:24+02:00 Antimicrobial Resistance of Enteric Salmonella in Bangui, Central African Republic Christian Diamant Mossoro-Kpinde Alexandre Manirakiza Jean-Robert Mbecko Pembé Misatou Alain Le Faou Thierry Frank 2015-01-01T00:00:00Z https://doi.org/10.1155/2015/483974 https://doaj.org/article/1ac17fb3b2e84e82800b4b35fd94ffc7 EN eng Hindawi Limited http://dx.doi.org/10.1155/2015/483974 https://doaj.org/toc/1687-9686 https://doaj.org/toc/1687-9694 1687-9686 1687-9694 doi:10.1155/2015/483974 https://doaj.org/article/1ac17fb3b2e84e82800b4b35fd94ffc7 Journal of Tropical Medicine, Vol 2015 (2015) Arctic medicine. Tropical medicine RC955-962 article 2015 ftdoajarticles https://doi.org/10.1155/2015/483974 2022-12-31T16:26:36Z Introduction. The number of Salmonella isolated from clinical samples that are resistant to multiple antibiotics has increased worldwide. The aim of this study was to determine the prevalence of resistant Salmonella enterica isolated in Bangui. Methods. All enteric Salmonella strains isolated from patients in 2008 were identified and serotyped, and the phenotypes of resistance were determined by using the disk diffusion method. Nine resistance-associated genes, blaTEM, blaOXA, blaSHV, tetA, aadA1, catA1, dhfrA1, sul I, and sul II, were sought by genic amplification in seven S.e. Typhimurium strains. Results. The 94 strains isolated consisted of 47 S.e. Typhimurium (50%), 21 S.e. Stanleyville (22%), 18 S.e. Enteritidis (19%), 4 S.e. Dublin (4%), 4 S.e. Hadar (4%), and 1 S.e. Papuana (1%). Twenty-five (28%) were multiresistant, including 20 of the Typhimurium serovar (80%). Two main phenotypes of resistance were found: four antibiotics (56%) and to five antibiotics (40%). One S.e. Typhimurium isolate produced an extended-spectrum β-lactamase (ESBL). Only seven strains of S.e. Typhimurium could be amplified genically. Only phenotypic resistance to tetracycline and aminosides was found. Conclusion. S. Typhimurium is the predominant serovar of enteric S. enterica and is the most widely resistant. The search for resistance genes showed heterogeneity of the circulating strains. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Journal of Tropical Medicine 2015 1 5 |
institution |
Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
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English |
topic |
Arctic medicine. Tropical medicine RC955-962 |
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Arctic medicine. Tropical medicine RC955-962 Christian Diamant Mossoro-Kpinde Alexandre Manirakiza Jean-Robert Mbecko Pembé Misatou Alain Le Faou Thierry Frank Antimicrobial Resistance of Enteric Salmonella in Bangui, Central African Republic |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 |
description |
Introduction. The number of Salmonella isolated from clinical samples that are resistant to multiple antibiotics has increased worldwide. The aim of this study was to determine the prevalence of resistant Salmonella enterica isolated in Bangui. Methods. All enteric Salmonella strains isolated from patients in 2008 were identified and serotyped, and the phenotypes of resistance were determined by using the disk diffusion method. Nine resistance-associated genes, blaTEM, blaOXA, blaSHV, tetA, aadA1, catA1, dhfrA1, sul I, and sul II, were sought by genic amplification in seven S.e. Typhimurium strains. Results. The 94 strains isolated consisted of 47 S.e. Typhimurium (50%), 21 S.e. Stanleyville (22%), 18 S.e. Enteritidis (19%), 4 S.e. Dublin (4%), 4 S.e. Hadar (4%), and 1 S.e. Papuana (1%). Twenty-five (28%) were multiresistant, including 20 of the Typhimurium serovar (80%). Two main phenotypes of resistance were found: four antibiotics (56%) and to five antibiotics (40%). One S.e. Typhimurium isolate produced an extended-spectrum β-lactamase (ESBL). Only seven strains of S.e. Typhimurium could be amplified genically. Only phenotypic resistance to tetracycline and aminosides was found. Conclusion. S. Typhimurium is the predominant serovar of enteric S. enterica and is the most widely resistant. The search for resistance genes showed heterogeneity of the circulating strains. |
format |
Article in Journal/Newspaper |
author |
Christian Diamant Mossoro-Kpinde Alexandre Manirakiza Jean-Robert Mbecko Pembé Misatou Alain Le Faou Thierry Frank |
author_facet |
Christian Diamant Mossoro-Kpinde Alexandre Manirakiza Jean-Robert Mbecko Pembé Misatou Alain Le Faou Thierry Frank |
author_sort |
Christian Diamant Mossoro-Kpinde |
title |
Antimicrobial Resistance of Enteric Salmonella in Bangui, Central African Republic |
title_short |
Antimicrobial Resistance of Enteric Salmonella in Bangui, Central African Republic |
title_full |
Antimicrobial Resistance of Enteric Salmonella in Bangui, Central African Republic |
title_fullStr |
Antimicrobial Resistance of Enteric Salmonella in Bangui, Central African Republic |
title_full_unstemmed |
Antimicrobial Resistance of Enteric Salmonella in Bangui, Central African Republic |
title_sort |
antimicrobial resistance of enteric salmonella in bangui, central african republic |
publisher |
Hindawi Limited |
publishDate |
2015 |
url |
https://doi.org/10.1155/2015/483974 https://doaj.org/article/1ac17fb3b2e84e82800b4b35fd94ffc7 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Journal of Tropical Medicine, Vol 2015 (2015) |
op_relation |
http://dx.doi.org/10.1155/2015/483974 https://doaj.org/toc/1687-9686 https://doaj.org/toc/1687-9694 1687-9686 1687-9694 doi:10.1155/2015/483974 https://doaj.org/article/1ac17fb3b2e84e82800b4b35fd94ffc7 |
op_doi |
https://doi.org/10.1155/2015/483974 |
container_title |
Journal of Tropical Medicine |
container_volume |
2015 |
container_start_page |
1 |
op_container_end_page |
5 |
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1766338911088410624 |