Pulmonary Blastomycosis in Vilas County, Wisconsin: Weather, Exposures and Symptoms
Purpose: Blastomycosis is a serious fungal infection contracted by inhalation of Blastomyces spores from the environment. Case occurrence in dogs in Vilas County, Wisconsin, has been associated with antecedent weather. We aimed to explore the effects of weather on the occurrence of human pulmonary b...
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Advocate Aurora Health
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ftdoajarticles:oai:doaj.org/article:1a72468a90bc4491881a695f2837844e 2023-05-15T17:36:28+02:00 Pulmonary Blastomycosis in Vilas County, Wisconsin: Weather, Exposures and Symptoms Dennis J. Baumgardner Kiley A. Bernhard Gina Egan 2015-01-01T00:00:00Z https://doi.org/10.17294/2330-0698.1050 https://doaj.org/article/1a72468a90bc4491881a695f2837844e EN eng Advocate Aurora Health http://digitalrepository.aurorahealthcare.org/cgi/viewcontent.cgi?article=1050&context=jpcrr https://doaj.org/toc/2330-0698 doi:10.17294/2330-0698.1050 2330-0698 https://doaj.org/article/1a72468a90bc4491881a695f2837844e Journal of Patient-Centered Research and Reviews, Vol 2, Iss 1, Pp 25-33 (2015) Blastomyces dermatitidis fungal ecology mycoses weather Medicine R article 2015 ftdoajarticles https://doi.org/10.17294/2330-0698.1050 2023-02-05T01:29:17Z Purpose: Blastomycosis is a serious fungal infection contracted by inhalation of Blastomyces spores from the environment. Case occurrence in dogs in Vilas County, Wisconsin, has been associated with antecedent weather. We aimed to explore the effects of weather on the occurrence of human pulmonary blastomycosis in this area, and update exposure factors and symptoms since last published reports. Methods: Mandatory case reports were reviewed. Chi-square test was used for categorical data of exposures, comparing 1979–1996 (n=101) versus 1997–June 2013 (n=95). Linear regression was used to model local weather data (available 1990–2013; n=126); Southern Oscillation Index (SOI), North Atlantic Oscillation Index (NAOI), and Wisconsin River water discharge (WRD) from the adjacent county (all available for 1984–2013; n=174); and case counts of known onset by warm (April–September) and cold (October–March) 6-month periods. Results: Distribution of pulmonary blastomycosis cases did not vary by season. Environmental exposures for the 1997–June 2013 group (mean age 45, 59% male) were: residence(76%), excavation (42%) and gardening (31%), all similar to the 1979–1996 group. Fishing (23% vs. 37%; P=0.09) and hunting (15% vs. 26%; P=0.13) exposures were less common in 1997–June 2013, but not significantly different. Overall, 69% of cases recalled some prior soil-disturbing activities. Considering the 6-month warm/cold periods, 19% of variation is explained by a direct relationship with total precipitation from two periods prior (P=0.005). There was no association of case occurrence with SOI, NAOI or WRD. Estimated annual incidence of blastomycosis for 1997–June 2013 was 27/100,000 compared with 44/100,000 for 1984–1996. Several symptoms were significantly less frequent in 2002–June 2013 compared to earlier years. Conclusions: As with dogs, human pulmonary blastomycosis occurrence is partially determined by antecedent precipitation. It is unclear if recent lower incidence rates are due to less opportunity for exposure to ... Article in Journal/Newspaper North Atlantic North Atlantic oscillation Directory of Open Access Journals: DOAJ Articles Soi ENVELOPE(30.704,30.704,66.481,66.481) Journal of Patient-Centered Research and Reviews 2 1 25 33 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Blastomyces dermatitidis fungal ecology mycoses weather Medicine R |
spellingShingle |
Blastomyces dermatitidis fungal ecology mycoses weather Medicine R Dennis J. Baumgardner Kiley A. Bernhard Gina Egan Pulmonary Blastomycosis in Vilas County, Wisconsin: Weather, Exposures and Symptoms |
topic_facet |
Blastomyces dermatitidis fungal ecology mycoses weather Medicine R |
description |
Purpose: Blastomycosis is a serious fungal infection contracted by inhalation of Blastomyces spores from the environment. Case occurrence in dogs in Vilas County, Wisconsin, has been associated with antecedent weather. We aimed to explore the effects of weather on the occurrence of human pulmonary blastomycosis in this area, and update exposure factors and symptoms since last published reports. Methods: Mandatory case reports were reviewed. Chi-square test was used for categorical data of exposures, comparing 1979–1996 (n=101) versus 1997–June 2013 (n=95). Linear regression was used to model local weather data (available 1990–2013; n=126); Southern Oscillation Index (SOI), North Atlantic Oscillation Index (NAOI), and Wisconsin River water discharge (WRD) from the adjacent county (all available for 1984–2013; n=174); and case counts of known onset by warm (April–September) and cold (October–March) 6-month periods. Results: Distribution of pulmonary blastomycosis cases did not vary by season. Environmental exposures for the 1997–June 2013 group (mean age 45, 59% male) were: residence(76%), excavation (42%) and gardening (31%), all similar to the 1979–1996 group. Fishing (23% vs. 37%; P=0.09) and hunting (15% vs. 26%; P=0.13) exposures were less common in 1997–June 2013, but not significantly different. Overall, 69% of cases recalled some prior soil-disturbing activities. Considering the 6-month warm/cold periods, 19% of variation is explained by a direct relationship with total precipitation from two periods prior (P=0.005). There was no association of case occurrence with SOI, NAOI or WRD. Estimated annual incidence of blastomycosis for 1997–June 2013 was 27/100,000 compared with 44/100,000 for 1984–1996. Several symptoms were significantly less frequent in 2002–June 2013 compared to earlier years. Conclusions: As with dogs, human pulmonary blastomycosis occurrence is partially determined by antecedent precipitation. It is unclear if recent lower incidence rates are due to less opportunity for exposure to ... |
format |
Article in Journal/Newspaper |
author |
Dennis J. Baumgardner Kiley A. Bernhard Gina Egan |
author_facet |
Dennis J. Baumgardner Kiley A. Bernhard Gina Egan |
author_sort |
Dennis J. Baumgardner |
title |
Pulmonary Blastomycosis in Vilas County, Wisconsin: Weather, Exposures and Symptoms |
title_short |
Pulmonary Blastomycosis in Vilas County, Wisconsin: Weather, Exposures and Symptoms |
title_full |
Pulmonary Blastomycosis in Vilas County, Wisconsin: Weather, Exposures and Symptoms |
title_fullStr |
Pulmonary Blastomycosis in Vilas County, Wisconsin: Weather, Exposures and Symptoms |
title_full_unstemmed |
Pulmonary Blastomycosis in Vilas County, Wisconsin: Weather, Exposures and Symptoms |
title_sort |
pulmonary blastomycosis in vilas county, wisconsin: weather, exposures and symptoms |
publisher |
Advocate Aurora Health |
publishDate |
2015 |
url |
https://doi.org/10.17294/2330-0698.1050 https://doaj.org/article/1a72468a90bc4491881a695f2837844e |
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ENVELOPE(30.704,30.704,66.481,66.481) |
geographic |
Soi |
geographic_facet |
Soi |
genre |
North Atlantic North Atlantic oscillation |
genre_facet |
North Atlantic North Atlantic oscillation |
op_source |
Journal of Patient-Centered Research and Reviews, Vol 2, Iss 1, Pp 25-33 (2015) |
op_relation |
http://digitalrepository.aurorahealthcare.org/cgi/viewcontent.cgi?article=1050&context=jpcrr https://doaj.org/toc/2330-0698 doi:10.17294/2330-0698.1050 2330-0698 https://doaj.org/article/1a72468a90bc4491881a695f2837844e |
op_doi |
https://doi.org/10.17294/2330-0698.1050 |
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Journal of Patient-Centered Research and Reviews |
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2 |
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1 |
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25 |
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33 |
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1766135948122259456 |