Hematological effects of Ipomoea batatas (camote) and Phyllanthus niruri (sampa-sampalukan) from Philippines in the ICR mice (Mus musculus)
Objective: To analyze the hematological effects of administering Ipomoea batatas (I. batatas) and Phyllanthus niruri (P. niruri) in the ICR mice. Methods: Powdered leaves of I. batatas and P. niruri were fed to mice for 4 weeks. A total of six groups were used to determine the effect of the plants t...
Published in: | Asian Pacific Journal of Tropical Biomedicine |
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Wolters Kluwer Medknow Publications
2015
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ftdoajarticles:oai:doaj.org/article:18ef8911044d422aa29ba11c8436b405 2023-05-15T15:15:25+02:00 Hematological effects of Ipomoea batatas (camote) and Phyllanthus niruri (sampa-sampalukan) from Philippines in the ICR mice (Mus musculus) Jessa Fidel Montejo Juan Arturo Burgos Mondonedo Matthew Genesis Aguila Lee Michael Bagui Ples Rodel Jonathan Santos Vitor II 2015-01-01T00:00:00Z https://doi.org/10.1016/S2221-1691(15)30166-0 https://doaj.org/article/18ef8911044d422aa29ba11c8436b405 EN eng Wolters Kluwer Medknow Publications http://www.sciencedirect.com/science/article/pii/S2221169115301660 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/S2221-1691(15)30166-0 https://doaj.org/article/18ef8911044d422aa29ba11c8436b405 Asian Pacific Journal of Tropical Biomedicine, Vol 5, Iss 1, Pp 29-33 (2015) Camote Hematology ICR mice Ipomea batatas Phyllanthus niruri Sampa-sampalukan Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 article 2015 ftdoajarticles https://doi.org/10.1016/S2221-1691(15)30166-0 2022-12-31T02:23:58Z Objective: To analyze the hematological effects of administering Ipomoea batatas (I. batatas) and Phyllanthus niruri (P. niruri) in the ICR mice. Methods: Powdered leaves of I. batatas and P. niruri were fed to mice for 4 weeks. A total of six groups were used to determine the effect of the plants to the complete blood count of the mouse. Group A (blank control) mice were feed with pellets only; Group B (negative control) mice were fed with pellets coated with honey; Group C (low dosage) mice were fed with honey-coated pellets and powdered leaves of I. batatas at 10 g/kg body weight of the mouse; Group D (high dosage) mice were fed with honey-coated pellets and powdered leaves of I. batatas at 20 g/kg body weight of the mouse; Group E (low dosage) mice were fed with honey-coated pellets and powdered leaves of P. niruri at 10 g/kg body weight of the mouse; and Group F (high dosage) mice were fed with honey-coated pellets and powdered leaves of P. niruri at 20 g/kg body weight of the mouse. Complete blood count was performed on Days 0, 14 and 28. Results: It was shown that I. batatas can increase the values of hematocrit and hemoglobin on both the low dose and high dose at Day 28 and red blood cells (RBC) on both Days 14 and 28 of testing. On the other hand, P. niruri can increase RBC, hematocrit and hemoglobin on Day 28 with only the low dose. There were no significant differences with white blood cell, absolute granulocyte, lymphocyte and monocyte, and platelet counts observed for both plant samples. Conclusions: I. batatas and P. niruri have effects on the hematocrit, RBC and hemoglobin levels in mice. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Asian Pacific Journal of Tropical Biomedicine 5 1 29 33 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Camote Hematology ICR mice Ipomea batatas Phyllanthus niruri Sampa-sampalukan Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
spellingShingle |
Camote Hematology ICR mice Ipomea batatas Phyllanthus niruri Sampa-sampalukan Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 Jessa Fidel Montejo Juan Arturo Burgos Mondonedo Matthew Genesis Aguila Lee Michael Bagui Ples Rodel Jonathan Santos Vitor II Hematological effects of Ipomoea batatas (camote) and Phyllanthus niruri (sampa-sampalukan) from Philippines in the ICR mice (Mus musculus) |
topic_facet |
Camote Hematology ICR mice Ipomea batatas Phyllanthus niruri Sampa-sampalukan Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
description |
Objective: To analyze the hematological effects of administering Ipomoea batatas (I. batatas) and Phyllanthus niruri (P. niruri) in the ICR mice. Methods: Powdered leaves of I. batatas and P. niruri were fed to mice for 4 weeks. A total of six groups were used to determine the effect of the plants to the complete blood count of the mouse. Group A (blank control) mice were feed with pellets only; Group B (negative control) mice were fed with pellets coated with honey; Group C (low dosage) mice were fed with honey-coated pellets and powdered leaves of I. batatas at 10 g/kg body weight of the mouse; Group D (high dosage) mice were fed with honey-coated pellets and powdered leaves of I. batatas at 20 g/kg body weight of the mouse; Group E (low dosage) mice were fed with honey-coated pellets and powdered leaves of P. niruri at 10 g/kg body weight of the mouse; and Group F (high dosage) mice were fed with honey-coated pellets and powdered leaves of P. niruri at 20 g/kg body weight of the mouse. Complete blood count was performed on Days 0, 14 and 28. Results: It was shown that I. batatas can increase the values of hematocrit and hemoglobin on both the low dose and high dose at Day 28 and red blood cells (RBC) on both Days 14 and 28 of testing. On the other hand, P. niruri can increase RBC, hematocrit and hemoglobin on Day 28 with only the low dose. There were no significant differences with white blood cell, absolute granulocyte, lymphocyte and monocyte, and platelet counts observed for both plant samples. Conclusions: I. batatas and P. niruri have effects on the hematocrit, RBC and hemoglobin levels in mice. |
format |
Article in Journal/Newspaper |
author |
Jessa Fidel Montejo Juan Arturo Burgos Mondonedo Matthew Genesis Aguila Lee Michael Bagui Ples Rodel Jonathan Santos Vitor II |
author_facet |
Jessa Fidel Montejo Juan Arturo Burgos Mondonedo Matthew Genesis Aguila Lee Michael Bagui Ples Rodel Jonathan Santos Vitor II |
author_sort |
Jessa Fidel Montejo |
title |
Hematological effects of Ipomoea batatas (camote) and Phyllanthus niruri (sampa-sampalukan) from Philippines in the ICR mice (Mus musculus) |
title_short |
Hematological effects of Ipomoea batatas (camote) and Phyllanthus niruri (sampa-sampalukan) from Philippines in the ICR mice (Mus musculus) |
title_full |
Hematological effects of Ipomoea batatas (camote) and Phyllanthus niruri (sampa-sampalukan) from Philippines in the ICR mice (Mus musculus) |
title_fullStr |
Hematological effects of Ipomoea batatas (camote) and Phyllanthus niruri (sampa-sampalukan) from Philippines in the ICR mice (Mus musculus) |
title_full_unstemmed |
Hematological effects of Ipomoea batatas (camote) and Phyllanthus niruri (sampa-sampalukan) from Philippines in the ICR mice (Mus musculus) |
title_sort |
hematological effects of ipomoea batatas (camote) and phyllanthus niruri (sampa-sampalukan) from philippines in the icr mice (mus musculus) |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2015 |
url |
https://doi.org/10.1016/S2221-1691(15)30166-0 https://doaj.org/article/18ef8911044d422aa29ba11c8436b405 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Asian Pacific Journal of Tropical Biomedicine, Vol 5, Iss 1, Pp 29-33 (2015) |
op_relation |
http://www.sciencedirect.com/science/article/pii/S2221169115301660 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/S2221-1691(15)30166-0 https://doaj.org/article/18ef8911044d422aa29ba11c8436b405 |
op_doi |
https://doi.org/10.1016/S2221-1691(15)30166-0 |
container_title |
Asian Pacific Journal of Tropical Biomedicine |
container_volume |
5 |
container_issue |
1 |
container_start_page |
29 |
op_container_end_page |
33 |
_version_ |
1766345781082587136 |