Avaliação hematológica e histopatológica de camundongos BALB/c e C57BL/6 expostos aos antígenos recombinantes Cytoplasmic Repetitive Antigen e Flagellar Repetitive Antigen de Trypanosoma cruzi Hematological and histopathological evaluation of BALB/c and C57BL/6 mice exposed to Cytoplasmic Repetitive Antigen and Flagellar Repetitive Antigen recombinant antigens of Trypanosoma cruzi

• Published in: Revista da Sociedade Brasileira de Medicina Tropical
• Main Authors: Valéria Rêgo Alves Pereira, Virginia Maria Barros de Lorena, Ana Paula Galvão-da Silva, Mineo Nakazawa, Edimilson Domingos da Silva, Antonio Gomes Pinto Ferreira, Ulisses Montarroyos, Eridan de Medeiros Coutinho, Yara de Miranda Gomes
• Format: Article in Journal/Newspaper
• Language: English
• Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2003
• Subjects: Trypanosoma cruzi; Antígenos recombinantes; Perfis hematológico; histopatológico; Recombinant antigens; Hematological and histological profiles; Arctic medicine. Tropical medicine; RC955-962; Arctic
• Online Access: https://doi.org/10.1590/S0037-86822003000600016; https://doaj.org/article/18c53367977a4d7a9f9999828ce313b8

Os antígenos recombinantes Cytoplasmic Repetitive Antigen e Flagellar Repetitive Antigen de Trypanosoma cruzi foram inoculados em camundongos BALB/c e C57BL/6 e o seu efeito avaliado a nível hematológico e histopatológico. Os resultados mostraram que o padrão histológico normal dos órgãos e o perfil hematológico dos camundongos não foram modificados sugerindo que esses antígenos não parecem causar dano ao animal. The Cytoplasmic Repetitive Antigen and Flagellar Repetitive Antigen recombinant antigens of Trypanosoma cruzi were inoculated into BALB/c and C57BL/6 mice and its effects evaluated at hematological and histopathological levels. The results showed that the histological pattern of the organs and the hematological profile of mice were not modified suggesting that these antigens are not harmful for the animal.