Application of anti-leptospira ELISA-lgM for the etiologic elucidation of meningitis Aplicação do ELISA-IgM anti-leptospira na elucidação etiológica das meningites
Leptospirosis is one of the causes of meningitis, although its importance is not well known. In the present study we contributed to this knowledge by demonstrating specific IgM class anti-leptospira antibodies by the immunoenzymatic method ELISA in 14.6% of cerebrospinal fluid (CSF) samples from 171...
Published in: | Revista do Instituto de Medicina Tropical de São Paulo |
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Universidade de São Paulo (USP)
1996
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Online Access: | https://doi.org/10.1590/S0036-46651996000200011 https://doaj.org/article/185654b750ad48afb5335a94d4da9b05 |
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ftdoajarticles:oai:doaj.org/article:185654b750ad48afb5335a94d4da9b05 2024-09-09T19:26:47+00:00 Application of anti-leptospira ELISA-lgM for the etiologic elucidation of meningitis Aplicação do ELISA-IgM anti-leptospira na elucidação etiológica das meningites Marcos V Silva Eide D Camargo Luíza Batista Adelaide J Vaz Antonio W Ferreira Paulo R.S. Barbosa 1996-04-01T00:00:00Z https://doi.org/10.1590/S0036-46651996000200011 https://doaj.org/article/185654b750ad48afb5335a94d4da9b05 EN eng Universidade de São Paulo (USP) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651996000200011 https://doaj.org/toc/0036-4665 https://doaj.org/toc/1678-9946 doi:10.1590/S0036-46651996000200011 0036-4665 1678-9946 https://doaj.org/article/185654b750ad48afb5335a94d4da9b05 Revista do Instituto de Medicina Tropical de São Paulo, Vol 38, Iss 2, Pp 153-156 (1996) Leptospirosis Meningitis and ELISA-IgM Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 1996 ftdoajarticles https://doi.org/10.1590/S0036-46651996000200011 2024-08-05T17:49:30Z Leptospirosis is one of the causes of meningitis, although its importance is not well known. In the present study we contributed to this knowledge by demonstrating specific IgM class anti-leptospira antibodies by the immunoenzymatic method ELISA in 14.6% of cerebrospinal fluid (CSF) samples from 171 patients with meningitis considered to be of indeterminate etiology. The frequencies of positivity were similar in cases with predominance of polymorphonuclear or lymphomononuclear leucocytes in the CSF. Age distribution showed a predominance of the 5 to 15 year age range (72%), and sex distribution showed a predominance of males (68%). The authors discuss the contribution of this method to the etiologic elucidation of meningitis. A Leptospirose é uma das causas de meningite, embora sua importância seja pouco conhecida. O presente estudo contribui para este conhecimento ao demonstrar anticorpos específicos da classe IgM anti-Leptospira pelo método imunoenzimático (ELISA), em 14,6% das amostras de líqüido cefalorraquianos (LCR) de 171 pacientes com meningite considerada de etiología indeterminada. As freqüências de positividade foram parecidas nos casos com predomínio no LCR de leucócitos polimorfonucleares ou linfomononucleares. A distribuição por idade mostrou predomínio na faixa etária entre 5 e 15 anos (72%) e por sexo o predomínio do masculino (68%). Os autores discutem a contribuição desse método na elucidação etiológica das meningites. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista do Instituto de Medicina Tropical de São Paulo 38 2 153 156 |
institution |
Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Leptospirosis Meningitis and ELISA-IgM Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
spellingShingle |
Leptospirosis Meningitis and ELISA-IgM Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Marcos V Silva Eide D Camargo Luíza Batista Adelaide J Vaz Antonio W Ferreira Paulo R.S. Barbosa Application of anti-leptospira ELISA-lgM for the etiologic elucidation of meningitis Aplicação do ELISA-IgM anti-leptospira na elucidação etiológica das meningites |
topic_facet |
Leptospirosis Meningitis and ELISA-IgM Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Leptospirosis is one of the causes of meningitis, although its importance is not well known. In the present study we contributed to this knowledge by demonstrating specific IgM class anti-leptospira antibodies by the immunoenzymatic method ELISA in 14.6% of cerebrospinal fluid (CSF) samples from 171 patients with meningitis considered to be of indeterminate etiology. The frequencies of positivity were similar in cases with predominance of polymorphonuclear or lymphomononuclear leucocytes in the CSF. Age distribution showed a predominance of the 5 to 15 year age range (72%), and sex distribution showed a predominance of males (68%). The authors discuss the contribution of this method to the etiologic elucidation of meningitis. A Leptospirose é uma das causas de meningite, embora sua importância seja pouco conhecida. O presente estudo contribui para este conhecimento ao demonstrar anticorpos específicos da classe IgM anti-Leptospira pelo método imunoenzimático (ELISA), em 14,6% das amostras de líqüido cefalorraquianos (LCR) de 171 pacientes com meningite considerada de etiología indeterminada. As freqüências de positividade foram parecidas nos casos com predomínio no LCR de leucócitos polimorfonucleares ou linfomononucleares. A distribuição por idade mostrou predomínio na faixa etária entre 5 e 15 anos (72%) e por sexo o predomínio do masculino (68%). Os autores discutem a contribuição desse método na elucidação etiológica das meningites. |
format |
Article in Journal/Newspaper |
author |
Marcos V Silva Eide D Camargo Luíza Batista Adelaide J Vaz Antonio W Ferreira Paulo R.S. Barbosa |
author_facet |
Marcos V Silva Eide D Camargo Luíza Batista Adelaide J Vaz Antonio W Ferreira Paulo R.S. Barbosa |
author_sort |
Marcos V Silva |
title |
Application of anti-leptospira ELISA-lgM for the etiologic elucidation of meningitis Aplicação do ELISA-IgM anti-leptospira na elucidação etiológica das meningites |
title_short |
Application of anti-leptospira ELISA-lgM for the etiologic elucidation of meningitis Aplicação do ELISA-IgM anti-leptospira na elucidação etiológica das meningites |
title_full |
Application of anti-leptospira ELISA-lgM for the etiologic elucidation of meningitis Aplicação do ELISA-IgM anti-leptospira na elucidação etiológica das meningites |
title_fullStr |
Application of anti-leptospira ELISA-lgM for the etiologic elucidation of meningitis Aplicação do ELISA-IgM anti-leptospira na elucidação etiológica das meningites |
title_full_unstemmed |
Application of anti-leptospira ELISA-lgM for the etiologic elucidation of meningitis Aplicação do ELISA-IgM anti-leptospira na elucidação etiológica das meningites |
title_sort |
application of anti-leptospira elisa-lgm for the etiologic elucidation of meningitis aplicação do elisa-igm anti-leptospira na elucidação etiológica das meningites |
publisher |
Universidade de São Paulo (USP) |
publishDate |
1996 |
url |
https://doi.org/10.1590/S0036-46651996000200011 https://doaj.org/article/185654b750ad48afb5335a94d4da9b05 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista do Instituto de Medicina Tropical de São Paulo, Vol 38, Iss 2, Pp 153-156 (1996) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651996000200011 https://doaj.org/toc/0036-4665 https://doaj.org/toc/1678-9946 doi:10.1590/S0036-46651996000200011 0036-4665 1678-9946 https://doaj.org/article/185654b750ad48afb5335a94d4da9b05 |
op_doi |
https://doi.org/10.1590/S0036-46651996000200011 |
container_title |
Revista do Instituto de Medicina Tropical de São Paulo |
container_volume |
38 |
container_issue |
2 |
container_start_page |
153 |
op_container_end_page |
156 |
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