Small cell lung cancer associated with multiple paraneoplastic syndromes

• Published in: Biomédica
• Main Authors: Diana L. Franco, Leslie Thomas
• Format: Article in Journal/Newspaper
• Language: English; Spanish
• Published: Instituto Nacional de Salud 2017
• Subjects: Lung neoplasms; paraneoplastic syndromes; electrolytes; Fanconi syndrome; Medicine; R; Arctic medicine. Tropical medicine; RC955-962; Arctic
• Online Access: https://doi.org/10.7705/biomedica.v37i1.2906; https://doaj.org/article/17a86a30b2b34d64856b50ea2474c928

We report the case of a patient presenting with multiple severe electrolyte disturbances who was subsequently found to have small cell lung cancer. Upon further evaluation, she demonstrated three distinct paraneoplastic processes, including the syndrome of inappropriate antidiuretic hormone, Fanconi syndrome, and an inappropriate elevation in fibroblast growth factor-23 (FGF23). The patient underwent one round of chemotherapy, but she was found to have progressive disease. After 36 days of hospitalization, the patient made the decision to enter hospice care and later she expired.