Disagreement between PCR and serological diagnosis of Trypanosoma cruzi infection in blood donors from a Colombian endemic region

• Published in: Biomédica
• Main Authors: Liliana Torcoroma García Sánchez, Jhancy Rocío Aguilar Jiménez, Marly Yojhana Bueno, Erika Marcela Moreno Moreno, Herminia Ramírez, Nelson Daza
• Format: Article in Journal/Newspaper
• Language: English; Spanish
• Published: Instituto Nacional de Salud 2021
• Subjects: trypanosoma cruzi; chagas disease; blood donors; serology; polymerase chain reaction; Medicine; R; Arctic medicine. Tropical medicine; RC955-962; Arctic; Abbott
• Online Access: https://doi.org/10.7705/biomedica.5441; https://doaj.org/article/17616fdd39f54a3cbdece87abb909e17

Introduction: Chagas’ disease is the leading cause of infectious myocarditis worldwide. This infection caused by Trypanosoma cruzi is usually life-long and asymptomatic; however, the third part of infected people can develop severe or even fatal cardiomyopathy. As the parasitemia in the chronic phas...