Repellent Activity of TRIG (N-N Diethyl Benzamide) against Man-Biting Mosquitoes

• Published in: Journal of Tropical Medicine
• Main Authors: Shandala Msangi, Eliningaya Kweka, Aneth Mahande
• Format: Article in Journal/Newspaper
• Language: English
• Published: Hindawi Limited 2018
• Subjects: Arctic medicine. Tropical medicine; RC955-962; Arctic; The Landing
• Online Access: https://doi.org/10.1155/2018/9037616; https://doaj.org/article/1747287d541a4b1497353b4a2b7e5d7a

A study was conducted to assess efficacy of a new repellent brand TRIG (15% N-N Diethyl Benzamide) when compared to DEET (20% N-N Methyl Toluamide). The repellents were tested in laboratory and field. In the laboratory, the repellence was tested on human volunteers, by exposing their repellent-treated arms on starved mosquitoes in cages for 3 minutes at hourly intervals, while counting the landing and probing attempts. Anopheles gambiae and Aedes aegypti mosquitoes were used. Field evaluation was conducted by Human Landing Catch technique. During the night, the repellents were applied on arms and legs and mosquitoes landing on these areas were collected. In laboratory tests, TRIG provided complete protection (100%) against Anopheles gambiae when applied at 1.25 g, while DEET provided this at 0.75 g. When tested on Aedes aegypti, TRIG provided complete protection when applied at 1 g, compared to 0.5 g for DEET. In the field, when applied at a recommended dose, both TRIG and DEET achieved above 90% protection against both An. arabiensis and Culex quinquefasciatus and a Complete Protection Time of about 6 hrs against both species of mosquitoes. The performances of the two products were found to be comparable and TRIG was recommended for use as repellent against mosquito bites.