Effectiveness of Preventive Vaccination against Hepatitis A in the Republic of Sakha (Yakutia)

• Published in: Problems of Particularly Dangerous Infections
• Main Authors: G. G. Onishchenko, M. E. Ignat’eva, L. V. Budatsyrenova, M. I. Mikhailov
• Format: Article in Journal/Newspaper
• Language: Russian
• Published: Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe” 2016
• Subjects: hepatitis a; preventive vaccination; the republic of sakha (yakutia); Infectious and parasitic diseases; RC109-216; Republic of Sakha; Yakutia
• Online Access: https://doi.org/10.21055/0370-1069-2016-3-44-46; https://doaj.org/article/16fc337221684ce79fe3cd11922e1bba

Objective of the study is to analyze the influence of vaccination against hepatitis A on the corresponding morbidity rates in the Republic of Sakha (Yakutia).Materials and methods: statistical data contained in the statutory forms of the State statistical reporting on infectious diseases and preventive vaccination against hepatitis A in Yakutia, dated 1992 to 2015.Results and conclusions. Following selective immunization of high-risk groups, performed during the last 14 years in the Republic of Sakha, the incidence of hepatitis A has decreased by 38 times. According to the results of 2015, registered were 15 cases of infection, the rate being 1.6 per 100 thousand of the population, which was below the national average by 2.8 times. Assessment of the long-term dynamics has demonstrated the impact of preventive vaccination on the epidemic process of hepatitis A. Morbidity rates fall down with the increment of the numbers of immunized persons. Effect of the vaccination among the age group of 7 to 14 years is especially strong.