Chlamydia trachomatis in Iceland: Prevalence, Clinico-epidemiological Features and Comparison of Cobas 480 CT/NG and Aptima Combo 2 (CT/NG) for Diagnosis
The aims of this study were to assess the prevalence of, and risk factors for, Chlamydia trachomatis in attendees recruited prospectively from October 2018 to January 2019 at the only sexually transmitted infections clinic in Iceland (in Reykjavík), and to evaluate the cobas 4800 CT/NG Test and Apti...
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Medical Journals Sweden
2021
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ftdoajarticles:oai:doaj.org/article:15df8e1488994a6a8dc20f12ee30a1be 2023-05-15T16:45:44+02:00 Chlamydia trachomatis in Iceland: Prevalence, Clinico-epidemiological Features and Comparison of Cobas 480 CT/NG and Aptima Combo 2 (CT/NG) for Diagnosis Ingibjorg Hilmarsdóttir Eva Mjöll Arnardóttir Elísabet Reykdal Jóhannesdóttir Daniel Golparian Magnus Unemo 2021-02-01T00:00:00Z https://doi.org/10.2340/00015555-3762 https://doaj.org/article/15df8e1488994a6a8dc20f12ee30a1be EN eng Medical Journals Sweden https://www.medicaljournals.se/acta/content/html/10.2340/00015555-3762 https://doaj.org/toc/0001-5555 https://doaj.org/toc/1651-2057 0001-5555 1651-2057 doi:10.2340/00015555-3762 https://doaj.org/article/15df8e1488994a6a8dc20f12ee30a1be Acta Dermato-Venereologica, Vol 101, Iss 2, p adv00393 (2021) chlamydia trachomatis neisseria gonorrhoeae prevalence risk factor nucleic acid amplification iceland sexually transmitted disease Dermatology RL1-803 article 2021 ftdoajarticles https://doi.org/10.2340/00015555-3762 2022-12-31T03:46:21Z The aims of this study were to assess the prevalence of, and risk factors for, Chlamydia trachomatis in attendees recruited prospectively from October 2018 to January 2019 at the only sexually transmitted infections clinic in Iceland (in Reykjavík), and to evaluate the cobas 4800 CT/NG Test and Aptima Combo 2 Assay for C. trachomatis detection in male urine and female vaginal swabs. Prevalence of C. trachomatis was 15.8% among 487 women and 13.6% among 491 men (no Neisseria gonorrhoeae positive patients were found). C. trachomatis detection was independently and positively associated with being tested for contact tracing, 18–24 years of age, and reporting ≥ 6 sexual partners within 12 months. Reporting sex with non-residents of Iceland was associated with a lower risk of C. trachomatis infection. Both assays had a high sensitivity in detection of C. trachomatis (Aptima Combo 2: 100%; cobas 4800 CT/NG: 95.1%) and high specificity (100% and 99.6%, respectively). The high local prevalence of C. trachomatis and increased acquisition risk following sex with residents are of public health concern. Article in Journal/Newspaper Iceland Reykjavík Reykjavík Directory of Open Access Journals: DOAJ Articles Reykjavík Acta Dermato Venereologica 101 2 adv00393 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
chlamydia trachomatis neisseria gonorrhoeae prevalence risk factor nucleic acid amplification iceland sexually transmitted disease Dermatology RL1-803 |
spellingShingle |
chlamydia trachomatis neisseria gonorrhoeae prevalence risk factor nucleic acid amplification iceland sexually transmitted disease Dermatology RL1-803 Ingibjorg Hilmarsdóttir Eva Mjöll Arnardóttir Elísabet Reykdal Jóhannesdóttir Daniel Golparian Magnus Unemo Chlamydia trachomatis in Iceland: Prevalence, Clinico-epidemiological Features and Comparison of Cobas 480 CT/NG and Aptima Combo 2 (CT/NG) for Diagnosis |
topic_facet |
chlamydia trachomatis neisseria gonorrhoeae prevalence risk factor nucleic acid amplification iceland sexually transmitted disease Dermatology RL1-803 |
description |
The aims of this study were to assess the prevalence of, and risk factors for, Chlamydia trachomatis in attendees recruited prospectively from October 2018 to January 2019 at the only sexually transmitted infections clinic in Iceland (in Reykjavík), and to evaluate the cobas 4800 CT/NG Test and Aptima Combo 2 Assay for C. trachomatis detection in male urine and female vaginal swabs. Prevalence of C. trachomatis was 15.8% among 487 women and 13.6% among 491 men (no Neisseria gonorrhoeae positive patients were found). C. trachomatis detection was independently and positively associated with being tested for contact tracing, 18–24 years of age, and reporting ≥ 6 sexual partners within 12 months. Reporting sex with non-residents of Iceland was associated with a lower risk of C. trachomatis infection. Both assays had a high sensitivity in detection of C. trachomatis (Aptima Combo 2: 100%; cobas 4800 CT/NG: 95.1%) and high specificity (100% and 99.6%, respectively). The high local prevalence of C. trachomatis and increased acquisition risk following sex with residents are of public health concern. |
format |
Article in Journal/Newspaper |
author |
Ingibjorg Hilmarsdóttir Eva Mjöll Arnardóttir Elísabet Reykdal Jóhannesdóttir Daniel Golparian Magnus Unemo |
author_facet |
Ingibjorg Hilmarsdóttir Eva Mjöll Arnardóttir Elísabet Reykdal Jóhannesdóttir Daniel Golparian Magnus Unemo |
author_sort |
Ingibjorg Hilmarsdóttir |
title |
Chlamydia trachomatis in Iceland: Prevalence, Clinico-epidemiological Features and Comparison of Cobas 480 CT/NG and Aptima Combo 2 (CT/NG) for Diagnosis |
title_short |
Chlamydia trachomatis in Iceland: Prevalence, Clinico-epidemiological Features and Comparison of Cobas 480 CT/NG and Aptima Combo 2 (CT/NG) for Diagnosis |
title_full |
Chlamydia trachomatis in Iceland: Prevalence, Clinico-epidemiological Features and Comparison of Cobas 480 CT/NG and Aptima Combo 2 (CT/NG) for Diagnosis |
title_fullStr |
Chlamydia trachomatis in Iceland: Prevalence, Clinico-epidemiological Features and Comparison of Cobas 480 CT/NG and Aptima Combo 2 (CT/NG) for Diagnosis |
title_full_unstemmed |
Chlamydia trachomatis in Iceland: Prevalence, Clinico-epidemiological Features and Comparison of Cobas 480 CT/NG and Aptima Combo 2 (CT/NG) for Diagnosis |
title_sort |
chlamydia trachomatis in iceland: prevalence, clinico-epidemiological features and comparison of cobas 480 ct/ng and aptima combo 2 (ct/ng) for diagnosis |
publisher |
Medical Journals Sweden |
publishDate |
2021 |
url |
https://doi.org/10.2340/00015555-3762 https://doaj.org/article/15df8e1488994a6a8dc20f12ee30a1be |
geographic |
Reykjavík |
geographic_facet |
Reykjavík |
genre |
Iceland Reykjavík Reykjavík |
genre_facet |
Iceland Reykjavík Reykjavík |
op_source |
Acta Dermato-Venereologica, Vol 101, Iss 2, p adv00393 (2021) |
op_relation |
https://www.medicaljournals.se/acta/content/html/10.2340/00015555-3762 https://doaj.org/toc/0001-5555 https://doaj.org/toc/1651-2057 0001-5555 1651-2057 doi:10.2340/00015555-3762 https://doaj.org/article/15df8e1488994a6a8dc20f12ee30a1be |
op_doi |
https://doi.org/10.2340/00015555-3762 |
container_title |
Acta Dermato Venereologica |
container_volume |
101 |
container_issue |
2 |
container_start_page |
adv00393 |
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1766035889997217792 |