Potential in vitro antimicrobial efficacy of Holigarna arnottiana (Hook F)
Objective: To explore the in vitro antimicrobial potential of Holigarna arnottiana (H. arnottiana) against human and shrimp pathogenic bacteria and use GC-MS analysis to elucidate its antimicrobial principles. Methods: In the present study, organic extract of H. arnottiana was examined for in vitro...
Published in: | Asian Pacific Journal of Tropical Biomedicine |
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Wolters Kluwer Medknow Publications
2014
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ftdoajarticles:oai:doaj.org/article:15aab5e040154aa38dfcdac7219afa62 2023-05-15T15:07:52+02:00 Potential in vitro antimicrobial efficacy of Holigarna arnottiana (Hook F) Aseer Manilal Akbar Idhayadhulla 2014-01-01T00:00:00Z https://doi.org/10.1016/S2221-1691(14)60203-3 https://doaj.org/article/15aab5e040154aa38dfcdac7219afa62 EN eng Wolters Kluwer Medknow Publications http://www.sciencedirect.com/science/article/pii/S2221169114602033 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/S2221-1691(14)60203-3 https://doaj.org/article/15aab5e040154aa38dfcdac7219afa62 Asian Pacific Journal of Tropical Biomedicine, Vol 4, Iss 1, Pp 25-29 (2014) Anacardiaceae Holigarna arnottiana Plant extract Bioactive compounds Chemical constituents Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 article 2014 ftdoajarticles https://doi.org/10.1016/S2221-1691(14)60203-3 2022-12-31T00:51:35Z Objective: To explore the in vitro antimicrobial potential of Holigarna arnottiana (H. arnottiana) against human and shrimp pathogenic bacteria and use GC-MS analysis to elucidate its antimicrobial principles. Methods: In the present study, organic extract of H. arnottiana was examined for in vitro antimicrobial potency against five clinical human pathogens, seven species of human type culture pathogens, six pathogenic Vibrio strains isolated from moribund tiger shrimp (Penaeus monodon) and seven type cultures (Microbial Type Culture Collection, MTCC) of prominent shrimp pathogens. Results: The extraction of H. arnottiana with ethyl acetate yielded bioactive crude extract that efficiently repressed the growth of all tested pathogens. Among the pathogens tested, shrimp pathogens were the most susceptible organisms while clinical pathogens were found to be a little resistant. The chemical constituents of the H. arnottiana were analysed by GC-MS which revealed the presence of major compounds such as 3,7,11,15-tetramethyl-2-hexadecen-1-o1 (42.1%), 1-lodo-2-methylundecane (34.5%) and squalene (11.1%) which might have a functional role in the chemical defence against microbial invasion. Conclusions: Based on the finding it could be inferred that H. arnottiana would be a reliable source for developing shrimp and human bio-therapeutics in future. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Asian Pacific Journal of Tropical Biomedicine 4 1 25 29 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Anacardiaceae Holigarna arnottiana Plant extract Bioactive compounds Chemical constituents Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
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Anacardiaceae Holigarna arnottiana Plant extract Bioactive compounds Chemical constituents Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 Aseer Manilal Akbar Idhayadhulla Potential in vitro antimicrobial efficacy of Holigarna arnottiana (Hook F) |
topic_facet |
Anacardiaceae Holigarna arnottiana Plant extract Bioactive compounds Chemical constituents Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
description |
Objective: To explore the in vitro antimicrobial potential of Holigarna arnottiana (H. arnottiana) against human and shrimp pathogenic bacteria and use GC-MS analysis to elucidate its antimicrobial principles. Methods: In the present study, organic extract of H. arnottiana was examined for in vitro antimicrobial potency against five clinical human pathogens, seven species of human type culture pathogens, six pathogenic Vibrio strains isolated from moribund tiger shrimp (Penaeus monodon) and seven type cultures (Microbial Type Culture Collection, MTCC) of prominent shrimp pathogens. Results: The extraction of H. arnottiana with ethyl acetate yielded bioactive crude extract that efficiently repressed the growth of all tested pathogens. Among the pathogens tested, shrimp pathogens were the most susceptible organisms while clinical pathogens were found to be a little resistant. The chemical constituents of the H. arnottiana were analysed by GC-MS which revealed the presence of major compounds such as 3,7,11,15-tetramethyl-2-hexadecen-1-o1 (42.1%), 1-lodo-2-methylundecane (34.5%) and squalene (11.1%) which might have a functional role in the chemical defence against microbial invasion. Conclusions: Based on the finding it could be inferred that H. arnottiana would be a reliable source for developing shrimp and human bio-therapeutics in future. |
format |
Article in Journal/Newspaper |
author |
Aseer Manilal Akbar Idhayadhulla |
author_facet |
Aseer Manilal Akbar Idhayadhulla |
author_sort |
Aseer Manilal |
title |
Potential in vitro antimicrobial efficacy of Holigarna arnottiana (Hook F) |
title_short |
Potential in vitro antimicrobial efficacy of Holigarna arnottiana (Hook F) |
title_full |
Potential in vitro antimicrobial efficacy of Holigarna arnottiana (Hook F) |
title_fullStr |
Potential in vitro antimicrobial efficacy of Holigarna arnottiana (Hook F) |
title_full_unstemmed |
Potential in vitro antimicrobial efficacy of Holigarna arnottiana (Hook F) |
title_sort |
potential in vitro antimicrobial efficacy of holigarna arnottiana (hook f) |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2014 |
url |
https://doi.org/10.1016/S2221-1691(14)60203-3 https://doaj.org/article/15aab5e040154aa38dfcdac7219afa62 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Asian Pacific Journal of Tropical Biomedicine, Vol 4, Iss 1, Pp 25-29 (2014) |
op_relation |
http://www.sciencedirect.com/science/article/pii/S2221169114602033 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/S2221-1691(14)60203-3 https://doaj.org/article/15aab5e040154aa38dfcdac7219afa62 |
op_doi |
https://doi.org/10.1016/S2221-1691(14)60203-3 |
container_title |
Asian Pacific Journal of Tropical Biomedicine |
container_volume |
4 |
container_issue |
1 |
container_start_page |
25 |
op_container_end_page |
29 |
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1766339273104031744 |