Impact of PGL-I seropositivity on the protective effect of BCG vaccination among leprosy contacts: a cohort study.

• Published in: PLoS Neglected Tropical Diseases
• Main Authors: Nádia C Düppre, Luiz Antonio B Camacho, Anna M Sales, Ximena Illarramendi, José Augusto C Nery, Elizabeth P Sampaio, Euzenir N Sarno, Samira Bührer-Sékula
• Format: Article in Journal/Newspaper
• Language: English
• Published: Public Library of Science (PLoS) 2012
• Subjects: Arctic medicine. Tropical medicine; RC955-962; Public aspects of medicine; RA1-1270; Arctic; Calmette
• Online Access: https://doi.org/10.1371/journal.pntd.0001711; https://doaj.org/article/14cce3aee537445abbe1efc8c8392b10

Background Contacts of leprosy patients are at increased risk of developing leprosy and need to be targeted for early diagnosis. Seropositivity to the phenolic glycolipid I (PGL-I) antigen of Mycobacterium leprae has been used to identify contacts who have an increased risk of developing leprosy. In...