ICR suckling mouse model of Zika virus infection for disease modeling and drug validation.

• Published in: PLOS Neglected Tropical Diseases
• Main Authors: Yu-Hsuan Wu, Chin-Kai Tseng, Chun-Kuang Lin, Chih-Ku Wei, Jin-Ching Lee, Kung-Chia Young
• Format: Article in Journal/Newspaper
• Language: English
• Published: Public Library of Science (PLoS) 2018
• Subjects: Arctic medicine. Tropical medicine; RC955-962; Public aspects of medicine; RA1-1270; Arctic; Barré
• Online Access: https://doi.org/10.1371/journal.pntd.0006848; https://doaj.org/article/14068a7aa30e4178970fbb21583627e4

BACKGROUND:Zika virus (ZIKV) infection causes diseases ranging from acute self-limiting febrile illness to life-threatening Guillain-Barré Syndrome and other neurological disorders in adults. Cumulative evidence suggests an association between ZIKV infection and microcephaly in newborn infants. Give...