Infection of the central nervous system with dengue virus 3 genotype I causing neurological manifestations in Brazil

• Published in: Revista da Sociedade Brasileira de Medicina Tropical
• Main Authors: Danilo Bretas de Oliveira, Guilherme Machado, Gabriel Magno de Freitas Almeida, Paulo César Peregrino Ferreira, Cláudio Antônio Bonjardim, Giliane de Souza Trindade, Jônatas Santos Abrahão, Erna Geessien Kroon
• Format: Article in Journal/Newspaper
• Language: English
• Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2016
• Subjects: Central nervous system; Neurologic manifestations of dengue vírus; Dengue virus 3 genotype I; Arctic medicine. Tropical medicine; RC955-962; Arctic
• Online Access: https://doi.org/10.1590/0037-8682-0208-2015; https://doaj.org/article/13af20ffea434b66ae8a88e7af88bdf6

Abstract: A case of dengue virus 3 (DENV-3) genotype I infection with neurological manifestations occurred in Belo Horizonte, Minas Gerais in October 2012. The serotype was detected by PCR, and the genotype was assessed by sequencing and phylogenetic analysis of the C-prM region. The virus causing neurological manifestations clustered with other sequences of DENV-3 genotype I. Because neurological manifestations of DENV are possibly misdiagnosed in Brazil, this study serves as an alert of the importance of DENV diagnoses in CNS infections.