Crystal structure of a MarR family protein from the psychrophilic bacterium Paenisporosarcina sp. TG-14 in complex with a lipid-like molecule

• Published in: IUCrJ
• Main Authors: Jisub Hwang, Sun-Ha Park, Chang Woo Lee, Hackwon Do, Seung Chul Shin, Han-Woo Kim, Sung Gu Lee, Hyun Ho Park, Sunghark Kwon, Jun Hyuck Lee
• Format: Article in Journal/Newspaper
• Language: English
• Published: International Union of Crystallography 2021
• Subjects: marr family proteins; transcription factors; psychrophilic bacteria; paenisporosarcina sp. tg-14; palmitic acid; conformational change; protein structure; molecular recognition; Crystallography; QD901-999; Marr; Antarc*; Antarctica
• Online Access: https://doi.org/10.1107/S2052252521005704; https://doaj.org/article/138b293da9254f87a2e0a52c60fff346

MarR family proteins regulate the transcription of multiple antibiotic-resistance genes and are widely found in bacteria and archaea. Recently, a new MarR family gene was identified by genome analysis of the psychrophilic bacterium Paenisporosarcina sp. TG-14, which was isolated from sediment-laden...