Retention of testicular integrity and testosterone levels upon ingestion of garlic cloves (Allium sativum) in the Sprague-Dawley rat
Objective: To investigate the effects of acute and chronic aqueous garlic extract ingestion on testicular cellular integrity and serum testosterone levels. Methods: Twenty (20) male Sprague-Dawley rats weighing an average of 120 g were used. Animals were divided into three groups. Group A served as...
Published in: | Asian Pacific Journal of Tropical Biomedicine |
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Wolters Kluwer Medknow Publications
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ftdoajarticles:oai:doaj.org/article:133fa08230ed4ecf8380a8754b62d319 2023-05-15T15:02:30+02:00 Retention of testicular integrity and testosterone levels upon ingestion of garlic cloves (Allium sativum) in the Sprague-Dawley rat Adejoke Elizabeth Memudu Ibukun Dorcas Akinrinade Olalekan Michael Ogundele 2015-04-01T00:00:00Z https://doi.org/10.1016/S2221-1691(15)30351-8 https://doaj.org/article/133fa08230ed4ecf8380a8754b62d319 EN eng Wolters Kluwer Medknow Publications http://www.sciencedirect.com/science/article/pii/S2221169115303518 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/S2221-1691(15)30351-8 https://doaj.org/article/133fa08230ed4ecf8380a8754b62d319 Asian Pacific Journal of Tropical Biomedicine, Vol 5, Iss 4, Pp 319-323 (2015) Allium sativum Testis Testosterone Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 article 2015 ftdoajarticles https://doi.org/10.1016/S2221-1691(15)30351-8 2022-12-30T21:14:44Z Objective: To investigate the effects of acute and chronic aqueous garlic extract ingestion on testicular cellular integrity and serum testosterone levels. Methods: Twenty (20) male Sprague-Dawley rats weighing an average of 120 g were used. Animals were divided into three groups. Group A served as control (10 rats for 28 and 56 d respectively), while treatment Groups B and C were given 200 mg/kg for Allium sativum (garlic cloves) extract for 28 and 56 d respectively. Results: Histological analysis revealed the presence of all spermatogenic lineages, appearance of proliferative activities in the interstitial cells, as well as increased serum testosterone levels. Conclusions: This study confirmed proliferative and restorative potentials in both acute and chronic garlic ingestion. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Asian Pacific Journal of Tropical Biomedicine 5 4 319 323 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Allium sativum Testis Testosterone Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
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Allium sativum Testis Testosterone Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 Adejoke Elizabeth Memudu Ibukun Dorcas Akinrinade Olalekan Michael Ogundele Retention of testicular integrity and testosterone levels upon ingestion of garlic cloves (Allium sativum) in the Sprague-Dawley rat |
topic_facet |
Allium sativum Testis Testosterone Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
description |
Objective: To investigate the effects of acute and chronic aqueous garlic extract ingestion on testicular cellular integrity and serum testosterone levels. Methods: Twenty (20) male Sprague-Dawley rats weighing an average of 120 g were used. Animals were divided into three groups. Group A served as control (10 rats for 28 and 56 d respectively), while treatment Groups B and C were given 200 mg/kg for Allium sativum (garlic cloves) extract for 28 and 56 d respectively. Results: Histological analysis revealed the presence of all spermatogenic lineages, appearance of proliferative activities in the interstitial cells, as well as increased serum testosterone levels. Conclusions: This study confirmed proliferative and restorative potentials in both acute and chronic garlic ingestion. |
format |
Article in Journal/Newspaper |
author |
Adejoke Elizabeth Memudu Ibukun Dorcas Akinrinade Olalekan Michael Ogundele |
author_facet |
Adejoke Elizabeth Memudu Ibukun Dorcas Akinrinade Olalekan Michael Ogundele |
author_sort |
Adejoke Elizabeth Memudu |
title |
Retention of testicular integrity and testosterone levels upon ingestion of garlic cloves (Allium sativum) in the Sprague-Dawley rat |
title_short |
Retention of testicular integrity and testosterone levels upon ingestion of garlic cloves (Allium sativum) in the Sprague-Dawley rat |
title_full |
Retention of testicular integrity and testosterone levels upon ingestion of garlic cloves (Allium sativum) in the Sprague-Dawley rat |
title_fullStr |
Retention of testicular integrity and testosterone levels upon ingestion of garlic cloves (Allium sativum) in the Sprague-Dawley rat |
title_full_unstemmed |
Retention of testicular integrity and testosterone levels upon ingestion of garlic cloves (Allium sativum) in the Sprague-Dawley rat |
title_sort |
retention of testicular integrity and testosterone levels upon ingestion of garlic cloves (allium sativum) in the sprague-dawley rat |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2015 |
url |
https://doi.org/10.1016/S2221-1691(15)30351-8 https://doaj.org/article/133fa08230ed4ecf8380a8754b62d319 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Asian Pacific Journal of Tropical Biomedicine, Vol 5, Iss 4, Pp 319-323 (2015) |
op_relation |
http://www.sciencedirect.com/science/article/pii/S2221169115303518 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/S2221-1691(15)30351-8 https://doaj.org/article/133fa08230ed4ecf8380a8754b62d319 |
op_doi |
https://doi.org/10.1016/S2221-1691(15)30351-8 |
container_title |
Asian Pacific Journal of Tropical Biomedicine |
container_volume |
5 |
container_issue |
4 |
container_start_page |
319 |
op_container_end_page |
323 |
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1766334453891727360 |