Retention of testicular integrity and testosterone levels upon ingestion of garlic cloves (Allium sativum) in the Sprague-Dawley rat
Objective: To investigate the effects of acute and chronic aqueous garlic extract ingestion on testicular cellular integrity and serum testosterone levels. Methods: Twenty (20) male Sprague-Dawley rats weighing an average of 120 g were used. Animals were divided into three groups. Group A served as...
| Published in: | Asian Pacific Journal of Tropical Biomedicine |
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| Main Authors: | , , |
| Format: | Article in Journal/Newspaper |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2015
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| Subjects: | |
| Online Access: | https://doi.org/10.1016/S2221-1691(15)30351-8 https://doaj.org/article/133fa08230ed4ecf8380a8754b62d319 |
| Summary: | Objective: To investigate the effects of acute and chronic aqueous garlic extract ingestion on testicular cellular integrity and serum testosterone levels. Methods: Twenty (20) male Sprague-Dawley rats weighing an average of 120 g were used. Animals were divided into three groups. Group A served as control (10 rats for 28 and 56 d respectively), while treatment Groups B and C were given 200 mg/kg for Allium sativum (garlic cloves) extract for 28 and 56 d respectively. Results: Histological analysis revealed the presence of all spermatogenic lineages, appearance of proliferative activities in the interstitial cells, as well as increased serum testosterone levels. Conclusions: This study confirmed proliferative and restorative potentials in both acute and chronic garlic ingestion. |
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