Fatal hemorrhagic–necrotizing pancreatitis associated with pancreatic and hepatic lipidosis in an obese Asian palm civet (Paradoxurus hermaphroditus)
Asian palm civets (Paradoxurus hermaphroditus), or toddy cats, belong to the family Viverridae. Little is known about the pathology of these animals and few articles have been published, mainly concerning their important role as wild reservoir hosts for severe infectious diseases of domestic animals...
Published in: | Asian Pacific Journal of Tropical Biomedicine |
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Wolters Kluwer Medknow Publications
2014
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ftdoajarticles:oai:doaj.org/article:132d4ac93b964fb7b07031298dc3db69 2023-05-15T15:08:47+02:00 Fatal hemorrhagic–necrotizing pancreatitis associated with pancreatic and hepatic lipidosis in an obese Asian palm civet (Paradoxurus hermaphroditus) Bongiovanni Laura Di Girolamo Nicola Montani Alessandro Della Salda Leonardo Selleri Paolo 2014-05-01T00:00:00Z https://doi.org/10.12980/APJTB.4.2014C915 https://doaj.org/article/132d4ac93b964fb7b07031298dc3db69 EN eng Wolters Kluwer Medknow Publications http://www.sciencedirect.com/science/article/pii/S2221169115302458 https://doaj.org/toc/2221-1691 2221-1691 doi:10.12980/APJTB.4.2014C915 https://doaj.org/article/132d4ac93b964fb7b07031298dc3db69 Asian Pacific Journal of Tropical Biomedicine, Vol 4, Iss S1, Pp S62-S65 (2014) Necrotizing pancreatitis Civet Viverridae Diet Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 article 2014 ftdoajarticles https://doi.org/10.12980/APJTB.4.2014C915 2022-12-31T03:55:29Z Asian palm civets (Paradoxurus hermaphroditus), or toddy cats, belong to the family Viverridae. Little is known about the pathology of these animals and few articles have been published, mainly concerning their important role as wild reservoir hosts for severe infectious diseases of domestic animals and human beings. A 4-year-old, female Asian palm civet was found dead by the owner. At necropsy, large amount of adipose tissue was found in the subcutis and in the peritoneal cavity. Most of the pancreas appeared red, translucent. Hepatomegaly, discoloration of the liver were evident, with multifocal areas of degeneration, characterized by white nodular lesions. Histologically, the pancreas showed severe interstitial and perilobular necrosis and extensive haemorrhages, with separation of the interstitium, mild reactive inflammation at the periphery of the pancreatic lobules. Liver showed multifocal foci of vacuolar degeneration, lipidic accumulation, sometimes associated to hepatocyte necrosis. A diagnosis of acute severe hemorrhagic-necrotizing pancreatitis (or acute pancreatic necrosis) associated with pancreatic and hepatic lipidosis was made. To the best of our knowledge, this represents the first case report of acute lethal pancreatitis in an Asian palm civet. Although the exact cause of the disease remains undetermined, a hypothesis of the cause and pathogenesis is discussed, pointing out dietary indiscretion and consequent overweight as possible important risk factors. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Asian Pacific Journal of Tropical Biomedicine 4 S62 S65 |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Necrotizing pancreatitis Civet Viverridae Diet Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
spellingShingle |
Necrotizing pancreatitis Civet Viverridae Diet Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 Bongiovanni Laura Di Girolamo Nicola Montani Alessandro Della Salda Leonardo Selleri Paolo Fatal hemorrhagic–necrotizing pancreatitis associated with pancreatic and hepatic lipidosis in an obese Asian palm civet (Paradoxurus hermaphroditus) |
topic_facet |
Necrotizing pancreatitis Civet Viverridae Diet Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
description |
Asian palm civets (Paradoxurus hermaphroditus), or toddy cats, belong to the family Viverridae. Little is known about the pathology of these animals and few articles have been published, mainly concerning their important role as wild reservoir hosts for severe infectious diseases of domestic animals and human beings. A 4-year-old, female Asian palm civet was found dead by the owner. At necropsy, large amount of adipose tissue was found in the subcutis and in the peritoneal cavity. Most of the pancreas appeared red, translucent. Hepatomegaly, discoloration of the liver were evident, with multifocal areas of degeneration, characterized by white nodular lesions. Histologically, the pancreas showed severe interstitial and perilobular necrosis and extensive haemorrhages, with separation of the interstitium, mild reactive inflammation at the periphery of the pancreatic lobules. Liver showed multifocal foci of vacuolar degeneration, lipidic accumulation, sometimes associated to hepatocyte necrosis. A diagnosis of acute severe hemorrhagic-necrotizing pancreatitis (or acute pancreatic necrosis) associated with pancreatic and hepatic lipidosis was made. To the best of our knowledge, this represents the first case report of acute lethal pancreatitis in an Asian palm civet. Although the exact cause of the disease remains undetermined, a hypothesis of the cause and pathogenesis is discussed, pointing out dietary indiscretion and consequent overweight as possible important risk factors. |
format |
Article in Journal/Newspaper |
author |
Bongiovanni Laura Di Girolamo Nicola Montani Alessandro Della Salda Leonardo Selleri Paolo |
author_facet |
Bongiovanni Laura Di Girolamo Nicola Montani Alessandro Della Salda Leonardo Selleri Paolo |
author_sort |
Bongiovanni Laura |
title |
Fatal hemorrhagic–necrotizing pancreatitis associated with pancreatic and hepatic lipidosis in an obese Asian palm civet (Paradoxurus hermaphroditus) |
title_short |
Fatal hemorrhagic–necrotizing pancreatitis associated with pancreatic and hepatic lipidosis in an obese Asian palm civet (Paradoxurus hermaphroditus) |
title_full |
Fatal hemorrhagic–necrotizing pancreatitis associated with pancreatic and hepatic lipidosis in an obese Asian palm civet (Paradoxurus hermaphroditus) |
title_fullStr |
Fatal hemorrhagic–necrotizing pancreatitis associated with pancreatic and hepatic lipidosis in an obese Asian palm civet (Paradoxurus hermaphroditus) |
title_full_unstemmed |
Fatal hemorrhagic–necrotizing pancreatitis associated with pancreatic and hepatic lipidosis in an obese Asian palm civet (Paradoxurus hermaphroditus) |
title_sort |
fatal hemorrhagic–necrotizing pancreatitis associated with pancreatic and hepatic lipidosis in an obese asian palm civet (paradoxurus hermaphroditus) |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2014 |
url |
https://doi.org/10.12980/APJTB.4.2014C915 https://doaj.org/article/132d4ac93b964fb7b07031298dc3db69 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Asian Pacific Journal of Tropical Biomedicine, Vol 4, Iss S1, Pp S62-S65 (2014) |
op_relation |
http://www.sciencedirect.com/science/article/pii/S2221169115302458 https://doaj.org/toc/2221-1691 2221-1691 doi:10.12980/APJTB.4.2014C915 https://doaj.org/article/132d4ac93b964fb7b07031298dc3db69 |
op_doi |
https://doi.org/10.12980/APJTB.4.2014C915 |
container_title |
Asian Pacific Journal of Tropical Biomedicine |
container_volume |
4 |
container_start_page |
S62 |
op_container_end_page |
S65 |
_version_ |
1766340085618311168 |