Seroprevalence of anti-Toxocara canis antibodies and associated risk factors among dog owners in the rural community of Nakhon Si Thammarat province, southern Thailand
Abstract Background Human toxocariasis is a zoonotic parasitic disease caused by the Toxocara canis and T. cati nematodes larvae. Dog owners are at a higher risk of acquiring T. canis infection, and there is no available evidence regarding the seroprevalence of T. canis infection among dog owners in...
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ftdoajarticles:oai:doaj.org/article:12d0ffa8e30842f980d95071e347d9b2 2023-05-15T15:16:49+02:00 Seroprevalence of anti-Toxocara canis antibodies and associated risk factors among dog owners in the rural community of Nakhon Si Thammarat province, southern Thailand Prasit Na-Ek Udomsak Narkkul Nonthapan Phasuk Chuchard Punsawad 2022-05-01T00:00:00Z https://doi.org/10.1186/s41182-022-00425-4 https://doaj.org/article/12d0ffa8e30842f980d95071e347d9b2 EN eng BMC https://doi.org/10.1186/s41182-022-00425-4 https://doaj.org/toc/1349-4147 doi:10.1186/s41182-022-00425-4 1349-4147 https://doaj.org/article/12d0ffa8e30842f980d95071e347d9b2 Tropical Medicine and Health, Vol 50, Iss 1, Pp 1-9 (2022) Seroprevalence Toxocara canis Dog owner Thailand Arctic medicine. Tropical medicine RC955-962 article 2022 ftdoajarticles https://doi.org/10.1186/s41182-022-00425-4 2022-12-31T02:38:07Z Abstract Background Human toxocariasis is a zoonotic parasitic disease caused by the Toxocara canis and T. cati nematodes larvae. Dog owners are at a higher risk of acquiring T. canis infection, and there is no available evidence regarding the seroprevalence of T. canis infection among dog owners in Thailand. Therefore, this study aimed to investigate the seroprevalence of T. canis infection and associated risk factors among dog owners in rural areas of Thailand. Methods A total of 132 dog owners, including 25 men and 107 women, were recruited for this study. Serum anti-T. canis IgG antibodies were detected using a commercial enzyme-linked immunosorbent assay (ELISA) kit, and information on risk factors was collected using a questionnaire. In addition, hematological parameters were analyzed by the auto hematology analyzer. Risk variables associated with T. canis infection were investigated using univariate and multivariate logistic regression models. Results The overall seroprevalence of T. canis was 76.5% (101/132). Men were more likely to be infected with T. canis than women. Univariate analysis revealed that dog owners who did not practice handwashing before meals (p = 0.005) or after contact with soil (p = 0.035) or dogs (p = 0.049) had a substantially higher risk of acquiring T. canis infection. After adjusting for confounders, not practicing handwashing before meals remained a significant risk factor for T. canis infection (p = 0.038). The mean number of eosinophils was significantly higher in the seropositive group than in the seronegative group. Conclusions This is the first serological report of T. canis infection among dog owners reflecting the high rate of T. canis seropositivity in rural areas of southern Thailand. This study also provides group-specific data concerning modifiable risk behaviors for more effective T. canis infection control and prevention strategies in Thailand. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Nakhon ENVELOPE(101.950,101.950,71.850,71.850) Tropical Medicine and Health 50 1 |
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Directory of Open Access Journals: DOAJ Articles |
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Seroprevalence Toxocara canis Dog owner Thailand Arctic medicine. Tropical medicine RC955-962 |
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Seroprevalence Toxocara canis Dog owner Thailand Arctic medicine. Tropical medicine RC955-962 Prasit Na-Ek Udomsak Narkkul Nonthapan Phasuk Chuchard Punsawad Seroprevalence of anti-Toxocara canis antibodies and associated risk factors among dog owners in the rural community of Nakhon Si Thammarat province, southern Thailand |
topic_facet |
Seroprevalence Toxocara canis Dog owner Thailand Arctic medicine. Tropical medicine RC955-962 |
description |
Abstract Background Human toxocariasis is a zoonotic parasitic disease caused by the Toxocara canis and T. cati nematodes larvae. Dog owners are at a higher risk of acquiring T. canis infection, and there is no available evidence regarding the seroprevalence of T. canis infection among dog owners in Thailand. Therefore, this study aimed to investigate the seroprevalence of T. canis infection and associated risk factors among dog owners in rural areas of Thailand. Methods A total of 132 dog owners, including 25 men and 107 women, were recruited for this study. Serum anti-T. canis IgG antibodies were detected using a commercial enzyme-linked immunosorbent assay (ELISA) kit, and information on risk factors was collected using a questionnaire. In addition, hematological parameters were analyzed by the auto hematology analyzer. Risk variables associated with T. canis infection were investigated using univariate and multivariate logistic regression models. Results The overall seroprevalence of T. canis was 76.5% (101/132). Men were more likely to be infected with T. canis than women. Univariate analysis revealed that dog owners who did not practice handwashing before meals (p = 0.005) or after contact with soil (p = 0.035) or dogs (p = 0.049) had a substantially higher risk of acquiring T. canis infection. After adjusting for confounders, not practicing handwashing before meals remained a significant risk factor for T. canis infection (p = 0.038). The mean number of eosinophils was significantly higher in the seropositive group than in the seronegative group. Conclusions This is the first serological report of T. canis infection among dog owners reflecting the high rate of T. canis seropositivity in rural areas of southern Thailand. This study also provides group-specific data concerning modifiable risk behaviors for more effective T. canis infection control and prevention strategies in Thailand. |
format |
Article in Journal/Newspaper |
author |
Prasit Na-Ek Udomsak Narkkul Nonthapan Phasuk Chuchard Punsawad |
author_facet |
Prasit Na-Ek Udomsak Narkkul Nonthapan Phasuk Chuchard Punsawad |
author_sort |
Prasit Na-Ek |
title |
Seroprevalence of anti-Toxocara canis antibodies and associated risk factors among dog owners in the rural community of Nakhon Si Thammarat province, southern Thailand |
title_short |
Seroprevalence of anti-Toxocara canis antibodies and associated risk factors among dog owners in the rural community of Nakhon Si Thammarat province, southern Thailand |
title_full |
Seroprevalence of anti-Toxocara canis antibodies and associated risk factors among dog owners in the rural community of Nakhon Si Thammarat province, southern Thailand |
title_fullStr |
Seroprevalence of anti-Toxocara canis antibodies and associated risk factors among dog owners in the rural community of Nakhon Si Thammarat province, southern Thailand |
title_full_unstemmed |
Seroprevalence of anti-Toxocara canis antibodies and associated risk factors among dog owners in the rural community of Nakhon Si Thammarat province, southern Thailand |
title_sort |
seroprevalence of anti-toxocara canis antibodies and associated risk factors among dog owners in the rural community of nakhon si thammarat province, southern thailand |
publisher |
BMC |
publishDate |
2022 |
url |
https://doi.org/10.1186/s41182-022-00425-4 https://doaj.org/article/12d0ffa8e30842f980d95071e347d9b2 |
long_lat |
ENVELOPE(101.950,101.950,71.850,71.850) |
geographic |
Arctic Nakhon |
geographic_facet |
Arctic Nakhon |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Tropical Medicine and Health, Vol 50, Iss 1, Pp 1-9 (2022) |
op_relation |
https://doi.org/10.1186/s41182-022-00425-4 https://doaj.org/toc/1349-4147 doi:10.1186/s41182-022-00425-4 1349-4147 https://doaj.org/article/12d0ffa8e30842f980d95071e347d9b2 |
op_doi |
https://doi.org/10.1186/s41182-022-00425-4 |
container_title |
Tropical Medicine and Health |
container_volume |
50 |
container_issue |
1 |
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1766347113697902592 |