Chagas disease among the Latin American adult population attending in a primary care center in Barcelona, Spain.
Background/aims The epidemiology of Chagas disease, until recently confined to areas of continental Latin America, has undergone considerable changes in recent decades due to migration to other parts of the world, including Spain. We studied the prevalence of Chagas disease in Latin American patient...
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ftdoajarticles:oai:doaj.org/article:126d1108fa7a40d698060806e4223661 2023-05-15T15:16:41+02:00 Chagas disease among the Latin American adult population attending in a primary care center in Barcelona, Spain. Carme Roca María Jesús Pinazo Paolo López-Chejade Joan Bayó Elizabeth Posada Jordi López-Solana Montserrat Gállego Montserrat Portús Joaquim Gascón Chagas-Clot Research Group 2011-04-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0001135 https://doaj.org/article/126d1108fa7a40d698060806e4223661 EN eng Public Library of Science (PLoS) https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21572511/?tool=EBI https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0001135 https://doaj.org/article/126d1108fa7a40d698060806e4223661 PLoS Neglected Tropical Diseases, Vol 5, Iss 4, p e1135 (2011) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2011 ftdoajarticles https://doi.org/10.1371/journal.pntd.0001135 2022-12-31T07:55:44Z Background/aims The epidemiology of Chagas disease, until recently confined to areas of continental Latin America, has undergone considerable changes in recent decades due to migration to other parts of the world, including Spain. We studied the prevalence of Chagas disease in Latin American patients treated at a health center in Barcelona and evaluated its clinical phase. We make some recommendations for screening for the disease. Methodology/principal findings We performed an observational, cross-sectional prevalence study by means of an immunochromatographic test screening of all continental Latin American patients over the age of 14 years visiting the health centre from October 2007 to October 2009. The diagnosis was confirmed by serological methods: conventional in-house ELISA (cELISA), a commercial kit (rELISA) and ELISA using T cruzi lysate (Ortho-Clinical Diagnostics) (oELISA). Of 766 patients studied, 22 were diagnosed with T. cruzi infection, showing a prevalence of 2.87% (95% CI, 1.6-4.12%). Of the infected patients, 45.45% men and 54.55% women, 21 were from Bolivia, showing a prevalence in the Bolivian subgroup (n=127) of 16.53% (95% CI, 9.6-23.39%). ALL THE INFECTED PATIENTS WERE IN A CHRONIC PHASE OF CHAGAS DISEASE: 81% with the indeterminate form, 9.5% with the cardiac form and 9.5% with the cardiodigestive form. All patients infected with T. cruzi had heard of Chagas disease in their country of origin, 82% knew someone affected, and 77% had a significant history of living in adobe houses in rural areas. Conclusions We found a high prevalence of T. cruzi infection in immigrants from Bolivia. Detection of T. cruzi-infected persons by screening programs in non-endemic countries would control non-vectorial transmission and would benefit the persons affected, public health and national health systems. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLoS Neglected Tropical Diseases 5 4 e1135 |
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Directory of Open Access Journals: DOAJ Articles |
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English |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Carme Roca María Jesús Pinazo Paolo López-Chejade Joan Bayó Elizabeth Posada Jordi López-Solana Montserrat Gállego Montserrat Portús Joaquim Gascón Chagas-Clot Research Group Chagas disease among the Latin American adult population attending in a primary care center in Barcelona, Spain. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Background/aims The epidemiology of Chagas disease, until recently confined to areas of continental Latin America, has undergone considerable changes in recent decades due to migration to other parts of the world, including Spain. We studied the prevalence of Chagas disease in Latin American patients treated at a health center in Barcelona and evaluated its clinical phase. We make some recommendations for screening for the disease. Methodology/principal findings We performed an observational, cross-sectional prevalence study by means of an immunochromatographic test screening of all continental Latin American patients over the age of 14 years visiting the health centre from October 2007 to October 2009. The diagnosis was confirmed by serological methods: conventional in-house ELISA (cELISA), a commercial kit (rELISA) and ELISA using T cruzi lysate (Ortho-Clinical Diagnostics) (oELISA). Of 766 patients studied, 22 were diagnosed with T. cruzi infection, showing a prevalence of 2.87% (95% CI, 1.6-4.12%). Of the infected patients, 45.45% men and 54.55% women, 21 were from Bolivia, showing a prevalence in the Bolivian subgroup (n=127) of 16.53% (95% CI, 9.6-23.39%). ALL THE INFECTED PATIENTS WERE IN A CHRONIC PHASE OF CHAGAS DISEASE: 81% with the indeterminate form, 9.5% with the cardiac form and 9.5% with the cardiodigestive form. All patients infected with T. cruzi had heard of Chagas disease in their country of origin, 82% knew someone affected, and 77% had a significant history of living in adobe houses in rural areas. Conclusions We found a high prevalence of T. cruzi infection in immigrants from Bolivia. Detection of T. cruzi-infected persons by screening programs in non-endemic countries would control non-vectorial transmission and would benefit the persons affected, public health and national health systems. |
format |
Article in Journal/Newspaper |
author |
Carme Roca María Jesús Pinazo Paolo López-Chejade Joan Bayó Elizabeth Posada Jordi López-Solana Montserrat Gállego Montserrat Portús Joaquim Gascón Chagas-Clot Research Group |
author_facet |
Carme Roca María Jesús Pinazo Paolo López-Chejade Joan Bayó Elizabeth Posada Jordi López-Solana Montserrat Gállego Montserrat Portús Joaquim Gascón Chagas-Clot Research Group |
author_sort |
Carme Roca |
title |
Chagas disease among the Latin American adult population attending in a primary care center in Barcelona, Spain. |
title_short |
Chagas disease among the Latin American adult population attending in a primary care center in Barcelona, Spain. |
title_full |
Chagas disease among the Latin American adult population attending in a primary care center in Barcelona, Spain. |
title_fullStr |
Chagas disease among the Latin American adult population attending in a primary care center in Barcelona, Spain. |
title_full_unstemmed |
Chagas disease among the Latin American adult population attending in a primary care center in Barcelona, Spain. |
title_sort |
chagas disease among the latin american adult population attending in a primary care center in barcelona, spain. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2011 |
url |
https://doi.org/10.1371/journal.pntd.0001135 https://doaj.org/article/126d1108fa7a40d698060806e4223661 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 5, Iss 4, p e1135 (2011) |
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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21572511/?tool=EBI https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0001135 https://doaj.org/article/126d1108fa7a40d698060806e4223661 |
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https://doi.org/10.1371/journal.pntd.0001135 |
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PLoS Neglected Tropical Diseases |
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4 |
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e1135 |
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