Risk factors associated with hantavirosis fatality: a regional analysis from a case-control study in Brazil
Introduction: In Brazil, hantavirus cardiopulmonary syndrome (HCPS) has a high lethality rate that varies by region. This study aimed to identify the risk factors associated with fatal hantavirosis. Methods: This study was a case-control study that included all laboratory confirmed cases of hantavir...
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ftdoajarticles:oai:doaj.org/article:1240b5879952406a86ffece1b9e8d24a 2023-05-15T15:12:42+02:00 Risk factors associated with hantavirosis fatality: a regional analysis from a case-control study in Brazil Maria Cristina Antunes Willemann Stefan Vilges de Oliveira 2014-01-01T00:00:00Z https://doi.org/10.1590/0037-8682-0243-2013 https://doaj.org/article/1240b5879952406a86ffece1b9e8d24a EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822014000100047&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0243-2013 https://doaj.org/article/1240b5879952406a86ffece1b9e8d24a Revista da Sociedade Brasileira de Medicina Tropical, Vol 47, Iss 1, Pp 47-51 (2014) Hantavirus infections Hantavirus syndrome Brazil Case-control studies Risk factors Arctic medicine. Tropical medicine RC955-962 article 2014 ftdoajarticles https://doi.org/10.1590/0037-8682-0243-2013 2022-12-31T02:54:53Z Introduction: In Brazil, hantavirus cardiopulmonary syndrome (HCPS) has a high lethality rate that varies by region. This study aimed to identify the risk factors associated with fatal hantavirosis. Methods: This study was a case-control study that included all laboratory confirmed cases of hantavirosis. The cases were stratified by the different Brazilian regions using data from the Notifiable Diseases Information System. “Cases” were patients who progressed to death, whereas “controls” were patients who were cured. The odds ratio (OR) and the adjusted OR were calculated. Results: Overall, 158 cases and 281 controls were included in this study. In the Midwest region, the cases were 60% less likely to present with flank pain, and the time between the beginning of symptoms and death was shorter than the time between the beginning of symptoms and a cure. In the Southeast region, the cases were 60% less likely to present with thrombocytopenia or reside in rural areas compared to those who progressed to a cure. Additionally, the cases sought medical assistance, notification and investigation more quickly than the controls. In the Southern region, the cases that died were 70% less likely to be male compared to the controls. Conclusions: HCPS manifests with nonspecific symptoms, and there are few published studies related to the condition, so determining a patient's therapeutic strategy is difficult. This study presents findings from different Brazilian regions and highlights the need for further investigations to improve comprehension about regional risk factors associated with hantavirosis and to reduce morbimortality. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista da Sociedade Brasileira de Medicina Tropical 47 1 47 51 |
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Directory of Open Access Journals: DOAJ Articles |
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English |
topic |
Hantavirus infections Hantavirus syndrome Brazil Case-control studies Risk factors Arctic medicine. Tropical medicine RC955-962 |
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Hantavirus infections Hantavirus syndrome Brazil Case-control studies Risk factors Arctic medicine. Tropical medicine RC955-962 Maria Cristina Antunes Willemann Stefan Vilges de Oliveira Risk factors associated with hantavirosis fatality: a regional analysis from a case-control study in Brazil |
topic_facet |
Hantavirus infections Hantavirus syndrome Brazil Case-control studies Risk factors Arctic medicine. Tropical medicine RC955-962 |
description |
Introduction: In Brazil, hantavirus cardiopulmonary syndrome (HCPS) has a high lethality rate that varies by region. This study aimed to identify the risk factors associated with fatal hantavirosis. Methods: This study was a case-control study that included all laboratory confirmed cases of hantavirosis. The cases were stratified by the different Brazilian regions using data from the Notifiable Diseases Information System. “Cases” were patients who progressed to death, whereas “controls” were patients who were cured. The odds ratio (OR) and the adjusted OR were calculated. Results: Overall, 158 cases and 281 controls were included in this study. In the Midwest region, the cases were 60% less likely to present with flank pain, and the time between the beginning of symptoms and death was shorter than the time between the beginning of symptoms and a cure. In the Southeast region, the cases were 60% less likely to present with thrombocytopenia or reside in rural areas compared to those who progressed to a cure. Additionally, the cases sought medical assistance, notification and investigation more quickly than the controls. In the Southern region, the cases that died were 70% less likely to be male compared to the controls. Conclusions: HCPS manifests with nonspecific symptoms, and there are few published studies related to the condition, so determining a patient's therapeutic strategy is difficult. This study presents findings from different Brazilian regions and highlights the need for further investigations to improve comprehension about regional risk factors associated with hantavirosis and to reduce morbimortality. |
format |
Article in Journal/Newspaper |
author |
Maria Cristina Antunes Willemann Stefan Vilges de Oliveira |
author_facet |
Maria Cristina Antunes Willemann Stefan Vilges de Oliveira |
author_sort |
Maria Cristina Antunes Willemann |
title |
Risk factors associated with hantavirosis fatality: a regional analysis from a case-control study in Brazil |
title_short |
Risk factors associated with hantavirosis fatality: a regional analysis from a case-control study in Brazil |
title_full |
Risk factors associated with hantavirosis fatality: a regional analysis from a case-control study in Brazil |
title_fullStr |
Risk factors associated with hantavirosis fatality: a regional analysis from a case-control study in Brazil |
title_full_unstemmed |
Risk factors associated with hantavirosis fatality: a regional analysis from a case-control study in Brazil |
title_sort |
risk factors associated with hantavirosis fatality: a regional analysis from a case-control study in brazil |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
2014 |
url |
https://doi.org/10.1590/0037-8682-0243-2013 https://doaj.org/article/1240b5879952406a86ffece1b9e8d24a |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 47, Iss 1, Pp 47-51 (2014) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822014000100047&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0243-2013 https://doaj.org/article/1240b5879952406a86ffece1b9e8d24a |
op_doi |
https://doi.org/10.1590/0037-8682-0243-2013 |
container_title |
Revista da Sociedade Brasileira de Medicina Tropical |
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47 |
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47 |
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51 |
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