From intervention to impact: modelling the potential mortality impact achievable by different long-lasting, insecticide-treated net delivery strategies
Abstract Background The current target of universal access to long-lasting, insecticide-treated nets (LLIN) is 80% coverage to reduce malaria deaths by 75% by 2015. So far, campaigns have been the main channel for large-scale delivery of LLINs, however the World Health Organization has recommended t...
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ftdoajarticles:oai:doaj.org/article:123fcbeb11614df385c4e7810ffcc387 2023-05-15T15:15:38+02:00 From intervention to impact: modelling the potential mortality impact achievable by different long-lasting, insecticide-treated net delivery strategies Okell Lucy C Paintain Lucy Webster Jayne Hanson Kara Lines Jo 2012-09-01T00:00:00Z https://doi.org/10.1186/1475-2875-11-327 https://doaj.org/article/123fcbeb11614df385c4e7810ffcc387 EN eng BMC http://www.malariajournal.com/content/11/1/327 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-11-327 1475-2875 https://doaj.org/article/123fcbeb11614df385c4e7810ffcc387 Malaria Journal, Vol 11, Iss 1, p 327 (2012) Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2012 ftdoajarticles https://doi.org/10.1186/1475-2875-11-327 2022-12-30T21:42:01Z Abstract Background The current target of universal access to long-lasting, insecticide-treated nets (LLIN) is 80% coverage to reduce malaria deaths by 75% by 2015. So far, campaigns have been the main channel for large-scale delivery of LLINs, however the World Health Organization has recommended that equal priority should be given to delivery via routine antenatal care (ANC) and immunization systems (EPI) to target pregnant women and children from birth. These various channels of LLIN delivery are targeted to children of different ages. Since risk of mortality varies with child age and LLIN effectiveness declines with net age, it was hypothesized that the age at which a child receives a new LLIN, and therefore the delivery channel, is important in optimizing the health impact of a net. Methods A simple dynamic mathematical model was developed of delivery and impact of LLINs among children under five years of age and their household members, incorporating data on age-specific malaria death rates, net use by household structure, and net efficacy over time. Results The presented analysis finds that supplementing a universal mass campaign with extra ANC delivery would achieve a 1.4 times higher mortality reduction than campaign delivery alone, reflecting that children born in the years between campaigns would otherwise have access to old nets or no nets at an age of high risk. The relative advantage of supplementary ANC delivery is still present though smaller if malaria transmission levels are lower or if there is a strong mass effect achieved by mass campaigns. Conclusion These results indicate that LLIN delivery policies must take into account the age of greatest malaria risk. Emphasis should be placed on supporting routine delivery of LLINs to young children as well as campaigns. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Malaria Journal 11 1 327 |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
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English |
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Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
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Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Okell Lucy C Paintain Lucy Webster Jayne Hanson Kara Lines Jo From intervention to impact: modelling the potential mortality impact achievable by different long-lasting, insecticide-treated net delivery strategies |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Background The current target of universal access to long-lasting, insecticide-treated nets (LLIN) is 80% coverage to reduce malaria deaths by 75% by 2015. So far, campaigns have been the main channel for large-scale delivery of LLINs, however the World Health Organization has recommended that equal priority should be given to delivery via routine antenatal care (ANC) and immunization systems (EPI) to target pregnant women and children from birth. These various channels of LLIN delivery are targeted to children of different ages. Since risk of mortality varies with child age and LLIN effectiveness declines with net age, it was hypothesized that the age at which a child receives a new LLIN, and therefore the delivery channel, is important in optimizing the health impact of a net. Methods A simple dynamic mathematical model was developed of delivery and impact of LLINs among children under five years of age and their household members, incorporating data on age-specific malaria death rates, net use by household structure, and net efficacy over time. Results The presented analysis finds that supplementing a universal mass campaign with extra ANC delivery would achieve a 1.4 times higher mortality reduction than campaign delivery alone, reflecting that children born in the years between campaigns would otherwise have access to old nets or no nets at an age of high risk. The relative advantage of supplementary ANC delivery is still present though smaller if malaria transmission levels are lower or if there is a strong mass effect achieved by mass campaigns. Conclusion These results indicate that LLIN delivery policies must take into account the age of greatest malaria risk. Emphasis should be placed on supporting routine delivery of LLINs to young children as well as campaigns. |
format |
Article in Journal/Newspaper |
author |
Okell Lucy C Paintain Lucy Webster Jayne Hanson Kara Lines Jo |
author_facet |
Okell Lucy C Paintain Lucy Webster Jayne Hanson Kara Lines Jo |
author_sort |
Okell Lucy C |
title |
From intervention to impact: modelling the potential mortality impact achievable by different long-lasting, insecticide-treated net delivery strategies |
title_short |
From intervention to impact: modelling the potential mortality impact achievable by different long-lasting, insecticide-treated net delivery strategies |
title_full |
From intervention to impact: modelling the potential mortality impact achievable by different long-lasting, insecticide-treated net delivery strategies |
title_fullStr |
From intervention to impact: modelling the potential mortality impact achievable by different long-lasting, insecticide-treated net delivery strategies |
title_full_unstemmed |
From intervention to impact: modelling the potential mortality impact achievable by different long-lasting, insecticide-treated net delivery strategies |
title_sort |
from intervention to impact: modelling the potential mortality impact achievable by different long-lasting, insecticide-treated net delivery strategies |
publisher |
BMC |
publishDate |
2012 |
url |
https://doi.org/10.1186/1475-2875-11-327 https://doaj.org/article/123fcbeb11614df385c4e7810ffcc387 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 11, Iss 1, p 327 (2012) |
op_relation |
http://www.malariajournal.com/content/11/1/327 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-11-327 1475-2875 https://doaj.org/article/123fcbeb11614df385c4e7810ffcc387 |
op_doi |
https://doi.org/10.1186/1475-2875-11-327 |
container_title |
Malaria Journal |
container_volume |
11 |
container_issue |
1 |
container_start_page |
327 |
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