Association between seroprevalence of IgG anti-Toxoplasma gondii and risk factors for infection among pregnant women in Climério de Oliveira Maternity, Salvador, Bahia, Brazil
ABSTRACT Maternal Toxoplasma gondii (T. gondii) infection can lead to spontaneous abortion, fetal malformation, and numerous sequelae in the newborn, including visual and hearing impairment. T. gondii serology was determined in pregnant women and their newborns who were referred to Climério de Olive...
Published in: | Revista do Instituto de Medicina Tropical de São Paulo |
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Universidade de São Paulo (USP)
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ftdoajarticles:oai:doaj.org/article:11836bfc327b42149a963f644b4ea52f 2024-09-09T19:26:47+00:00 Association between seroprevalence of IgG anti-Toxoplasma gondii and risk factors for infection among pregnant women in Climério de Oliveira Maternity, Salvador, Bahia, Brazil Maria Virginia Avelar Victor Otero Martinez Daniel Lima de Moura Indira Alves Barros Anderson Alves da Silva Primo Alan Oliveira Duarte Neci Matos Soares Fernanda Washington de Mendonça Lima 2017-12-01T00:00:00Z https://doi.org/10.1590/s1678-9946201759090 https://doaj.org/article/11836bfc327b42149a963f644b4ea52f EN eng Universidade de São Paulo (USP) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652017005000254&lng=en&tlng=en https://doaj.org/toc/1678-9946 1678-9946 doi:10.1590/s1678-9946201759090 https://doaj.org/article/11836bfc327b42149a963f644b4ea52f Revista do Instituto de Medicina Tropical de São Paulo, Vol 59, Iss 0 (2017) Toxoplasmosis Prevalence Infection Pregnant women Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2017 ftdoajarticles https://doi.org/10.1590/s1678-9946201759090 2024-08-05T17:49:31Z ABSTRACT Maternal Toxoplasma gondii (T. gondii) infection can lead to spontaneous abortion, fetal malformation, and numerous sequelae in the newborn, including visual and hearing impairment. T. gondii serology was determined in pregnant women and their newborns who were referred to Climério de Oliveira Maternity, Federal University of Bahia, and the possible associations with the risk factors for maternal infection were investigated. This cross-sectional study was conducted from January to December 2014 and included 712 pregnant women, aged 15 to 49 years, and 235 newborns. Seroprevalence was determined by the detection of T. gondii-specific immunoglobulin (Ig) M (IgM) and IgG antibodies using enzyme-linked immunoassay. In addition, mothers completed a questionnaire that focused on socioeconomic aspects, and survey data were tabulated using the SPSS statistical software program (version 21.0 for Windows). The seroprevalence rate for specific IgG antibodies was 51% (362) among mothers and 93% (219) among neonates. All the mothers and their newborns were negative for specific-IgM antibodies. Higher age group and lower maternal education were the only risk factors statistically associated with the presence of specific IgG. In summary, high levels of specific IgG antibodies were observed in pregnant women. The knowledge of risk factors for toxoplasmosis can help in the orientation of newly pregnant women. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista do Instituto de Medicina Tropical de São Paulo 59 0 |
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English |
topic |
Toxoplasmosis Prevalence Infection Pregnant women Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
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Toxoplasmosis Prevalence Infection Pregnant women Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Maria Virginia Avelar Victor Otero Martinez Daniel Lima de Moura Indira Alves Barros Anderson Alves da Silva Primo Alan Oliveira Duarte Neci Matos Soares Fernanda Washington de Mendonça Lima Association between seroprevalence of IgG anti-Toxoplasma gondii and risk factors for infection among pregnant women in Climério de Oliveira Maternity, Salvador, Bahia, Brazil |
topic_facet |
Toxoplasmosis Prevalence Infection Pregnant women Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
ABSTRACT Maternal Toxoplasma gondii (T. gondii) infection can lead to spontaneous abortion, fetal malformation, and numerous sequelae in the newborn, including visual and hearing impairment. T. gondii serology was determined in pregnant women and their newborns who were referred to Climério de Oliveira Maternity, Federal University of Bahia, and the possible associations with the risk factors for maternal infection were investigated. This cross-sectional study was conducted from January to December 2014 and included 712 pregnant women, aged 15 to 49 years, and 235 newborns. Seroprevalence was determined by the detection of T. gondii-specific immunoglobulin (Ig) M (IgM) and IgG antibodies using enzyme-linked immunoassay. In addition, mothers completed a questionnaire that focused on socioeconomic aspects, and survey data were tabulated using the SPSS statistical software program (version 21.0 for Windows). The seroprevalence rate for specific IgG antibodies was 51% (362) among mothers and 93% (219) among neonates. All the mothers and their newborns were negative for specific-IgM antibodies. Higher age group and lower maternal education were the only risk factors statistically associated with the presence of specific IgG. In summary, high levels of specific IgG antibodies were observed in pregnant women. The knowledge of risk factors for toxoplasmosis can help in the orientation of newly pregnant women. |
format |
Article in Journal/Newspaper |
author |
Maria Virginia Avelar Victor Otero Martinez Daniel Lima de Moura Indira Alves Barros Anderson Alves da Silva Primo Alan Oliveira Duarte Neci Matos Soares Fernanda Washington de Mendonça Lima |
author_facet |
Maria Virginia Avelar Victor Otero Martinez Daniel Lima de Moura Indira Alves Barros Anderson Alves da Silva Primo Alan Oliveira Duarte Neci Matos Soares Fernanda Washington de Mendonça Lima |
author_sort |
Maria Virginia Avelar |
title |
Association between seroprevalence of IgG anti-Toxoplasma gondii and risk factors for infection among pregnant women in Climério de Oliveira Maternity, Salvador, Bahia, Brazil |
title_short |
Association between seroprevalence of IgG anti-Toxoplasma gondii and risk factors for infection among pregnant women in Climério de Oliveira Maternity, Salvador, Bahia, Brazil |
title_full |
Association between seroprevalence of IgG anti-Toxoplasma gondii and risk factors for infection among pregnant women in Climério de Oliveira Maternity, Salvador, Bahia, Brazil |
title_fullStr |
Association between seroprevalence of IgG anti-Toxoplasma gondii and risk factors for infection among pregnant women in Climério de Oliveira Maternity, Salvador, Bahia, Brazil |
title_full_unstemmed |
Association between seroprevalence of IgG anti-Toxoplasma gondii and risk factors for infection among pregnant women in Climério de Oliveira Maternity, Salvador, Bahia, Brazil |
title_sort |
association between seroprevalence of igg anti-toxoplasma gondii and risk factors for infection among pregnant women in climério de oliveira maternity, salvador, bahia, brazil |
publisher |
Universidade de São Paulo (USP) |
publishDate |
2017 |
url |
https://doi.org/10.1590/s1678-9946201759090 https://doaj.org/article/11836bfc327b42149a963f644b4ea52f |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista do Instituto de Medicina Tropical de São Paulo, Vol 59, Iss 0 (2017) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652017005000254&lng=en&tlng=en https://doaj.org/toc/1678-9946 1678-9946 doi:10.1590/s1678-9946201759090 https://doaj.org/article/11836bfc327b42149a963f644b4ea52f |
op_doi |
https://doi.org/10.1590/s1678-9946201759090 |
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Revista do Instituto de Medicina Tropical de São Paulo |
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59 |
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