Co-infections of malaria and geohelminthiasis in two rural communities of Nkassomo and Vian in the Mfou health district, Cameroon.
Background Human co-infection with malaria and helmimths is ubiquitous throughout Africa. Nevertheless, its public health significance on malaria severity remains poorly understood. Methodology/principal findings To contribute to a better understanding of epidemiology and control of this co-infectio...
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ftdoajarticles:oai:doaj.org/article:112fc5a953314befa0b82ce6f7457422 2023-05-15T15:15:16+02:00 Co-infections of malaria and geohelminthiasis in two rural communities of Nkassomo and Vian in the Mfou health district, Cameroon. Francis Zeukeng Viviane Hélène Matong Tchinda Jude Daiga Bigoga Clovis Hugues Tiogang Seumen Edward Shafe Ndzi Géraldine Abonweh Valérie Makoge Amédée Motsebo Roger Somo Moyou 2014-10-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0003236 https://doaj.org/article/112fc5a953314befa0b82ce6f7457422 EN eng Public Library of Science (PLoS) https://doi.org/10.1371/journal.pntd.0003236 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0003236 https://doaj.org/article/112fc5a953314befa0b82ce6f7457422 PLoS Neglected Tropical Diseases, Vol 8, Iss 10, p e3236 (2014) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2014 ftdoajarticles https://doi.org/10.1371/journal.pntd.0003236 2022-12-31T15:49:44Z Background Human co-infection with malaria and helmimths is ubiquitous throughout Africa. Nevertheless, its public health significance on malaria severity remains poorly understood. Methodology/principal findings To contribute to a better understanding of epidemiology and control of this co-infection in Cameroon, a cross-sectional study was carried out to assess the prevalence of concomitant intestinal geohelminthiasis and malaria, and to evaluate its association with malaria and anaemia in Nkassomo and Vian. Finger prick blood specimens from a total of 263 participants aged 1-95 years were collected for malaria microscopy, assessment of haemoglobin levels, and molecular identification of Plasmodium species by PCR. Fresh stool specimens were also collected for the identification and quantification of geohelminths by the Kato-Katz method. The prevalence of malaria, geohelminths, and co-infections were 77.2%, 28.6%, and 22.1%, respectively. Plasmodium falciparum was the only malaria parasite species identified with mean parasite density of 111 (40; 18,800) parasites/µl of blood. The geohelminths found were Ascaris lumbricoides (21.6%) and Trichuris trichiura (10.8%), with mean parasite densities of 243 (24; 3,552) and 36 (24; 96) eggs/gram of faeces, respectively. Co-infections of A. lumbricoides and P. falciparum were the most frequent and correlated positively. While no significant difference was observed on the prevalences of single and co-infections between the two localities, there was a significant difference in the density of A. lumbricoides infection between the two localities. The overall prevalence of anaemia was 42%, with individuals co-infected with T. trichiura and P. falciparum (60%) being the most at risk. While the prevalence of malaria and anaemia were inversely related to age, children aged 5-14 years were more susceptible to geohelminthiasis and their co-infections with malaria. Conclusion/significance Co-existence of geohelminths and malaria parasites in Nkassomo and Vian enhances the ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Vian ENVELOPE(13.642,13.642,68.185,68.185) PLoS Neglected Tropical Diseases 8 10 e3236 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Francis Zeukeng Viviane Hélène Matong Tchinda Jude Daiga Bigoga Clovis Hugues Tiogang Seumen Edward Shafe Ndzi Géraldine Abonweh Valérie Makoge Amédée Motsebo Roger Somo Moyou Co-infections of malaria and geohelminthiasis in two rural communities of Nkassomo and Vian in the Mfou health district, Cameroon. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Background Human co-infection with malaria and helmimths is ubiquitous throughout Africa. Nevertheless, its public health significance on malaria severity remains poorly understood. Methodology/principal findings To contribute to a better understanding of epidemiology and control of this co-infection in Cameroon, a cross-sectional study was carried out to assess the prevalence of concomitant intestinal geohelminthiasis and malaria, and to evaluate its association with malaria and anaemia in Nkassomo and Vian. Finger prick blood specimens from a total of 263 participants aged 1-95 years were collected for malaria microscopy, assessment of haemoglobin levels, and molecular identification of Plasmodium species by PCR. Fresh stool specimens were also collected for the identification and quantification of geohelminths by the Kato-Katz method. The prevalence of malaria, geohelminths, and co-infections were 77.2%, 28.6%, and 22.1%, respectively. Plasmodium falciparum was the only malaria parasite species identified with mean parasite density of 111 (40; 18,800) parasites/µl of blood. The geohelminths found were Ascaris lumbricoides (21.6%) and Trichuris trichiura (10.8%), with mean parasite densities of 243 (24; 3,552) and 36 (24; 96) eggs/gram of faeces, respectively. Co-infections of A. lumbricoides and P. falciparum were the most frequent and correlated positively. While no significant difference was observed on the prevalences of single and co-infections between the two localities, there was a significant difference in the density of A. lumbricoides infection between the two localities. The overall prevalence of anaemia was 42%, with individuals co-infected with T. trichiura and P. falciparum (60%) being the most at risk. While the prevalence of malaria and anaemia were inversely related to age, children aged 5-14 years were more susceptible to geohelminthiasis and their co-infections with malaria. Conclusion/significance Co-existence of geohelminths and malaria parasites in Nkassomo and Vian enhances the ... |
format |
Article in Journal/Newspaper |
author |
Francis Zeukeng Viviane Hélène Matong Tchinda Jude Daiga Bigoga Clovis Hugues Tiogang Seumen Edward Shafe Ndzi Géraldine Abonweh Valérie Makoge Amédée Motsebo Roger Somo Moyou |
author_facet |
Francis Zeukeng Viviane Hélène Matong Tchinda Jude Daiga Bigoga Clovis Hugues Tiogang Seumen Edward Shafe Ndzi Géraldine Abonweh Valérie Makoge Amédée Motsebo Roger Somo Moyou |
author_sort |
Francis Zeukeng |
title |
Co-infections of malaria and geohelminthiasis in two rural communities of Nkassomo and Vian in the Mfou health district, Cameroon. |
title_short |
Co-infections of malaria and geohelminthiasis in two rural communities of Nkassomo and Vian in the Mfou health district, Cameroon. |
title_full |
Co-infections of malaria and geohelminthiasis in two rural communities of Nkassomo and Vian in the Mfou health district, Cameroon. |
title_fullStr |
Co-infections of malaria and geohelminthiasis in two rural communities of Nkassomo and Vian in the Mfou health district, Cameroon. |
title_full_unstemmed |
Co-infections of malaria and geohelminthiasis in two rural communities of Nkassomo and Vian in the Mfou health district, Cameroon. |
title_sort |
co-infections of malaria and geohelminthiasis in two rural communities of nkassomo and vian in the mfou health district, cameroon. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2014 |
url |
https://doi.org/10.1371/journal.pntd.0003236 https://doaj.org/article/112fc5a953314befa0b82ce6f7457422 |
long_lat |
ENVELOPE(13.642,13.642,68.185,68.185) |
geographic |
Arctic Vian |
geographic_facet |
Arctic Vian |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 8, Iss 10, p e3236 (2014) |
op_relation |
https://doi.org/10.1371/journal.pntd.0003236 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0003236 https://doaj.org/article/112fc5a953314befa0b82ce6f7457422 |
op_doi |
https://doi.org/10.1371/journal.pntd.0003236 |
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PLoS Neglected Tropical Diseases |
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e3236 |
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