Identification of pyrimethamine- and chloroquine-resistant Plasmodium falciparum in Africa between 1984 and 1998: genotyping of archive blood samples

• Published in: Malaria Journal
• Main Authors: Saito-Nakano Yumiko, Tanabe Kazuyuki, Mita Toshihiro
• Format: Article in Journal/Newspaper
• Language: English
• Published: BMC 2011
• Subjects: Plasmodium falciparum; Drug resistance; Chloroquine; pfcrt; Pyrimethamine; dhfr; Africa; Archive sample; Arctic medicine. Tropical medicine; RC955-962; Infectious and parasitic diseases; RC109-216; Arctic; Irni
• Online Access: https://doi.org/10.1186/1475-2875-10-388; https://doaj.org/article/110334dfc18942969f5b68231efd5b44

Abstract Background Understanding the geographical distribution of drug resistance of Plasmodium falciparum is important for the effective treatment of malaria. Drug resistance has previously been inferred mainly from records of clinical resistance. However, clinical resistance is not always consist...