Seroprevalence of varicella zoster virus in Colombo district, Sri Lanka
Objective: To determine the seroprevalence of varicella zoster virus (VZV) antibodies among the population residing in the Colombo district of Sri Lanka. Methods: A cross-sectional population-based study was conducted which included 1 258 participants. Blood samples were collected and questionnaires...
Published in: | Asian Pacific Journal of Tropical Medicine |
---|---|
Main Authors: | , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2018
|
Subjects: | |
Online Access: | https://doi.org/10.4103/1995-7645.223561 https://doaj.org/article/0e609709671d48acba2b600af2c97af9 |
id |
ftdoajarticles:oai:doaj.org/article:0e609709671d48acba2b600af2c97af9 |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:0e609709671d48acba2b600af2c97af9 2023-05-15T15:08:42+02:00 Seroprevalence of varicella zoster virus in Colombo district, Sri Lanka Hathshya M Munasingha Ananda Amarasinghe Neelika G Malavige Nalini Sathiakumar 2018-01-01T00:00:00Z https://doi.org/10.4103/1995-7645.223561 https://doaj.org/article/0e609709671d48acba2b600af2c97af9 EN eng Wolters Kluwer Medknow Publications http://www.apjtm.org/article.asp?issn=1995-7645;year=2018;volume=11;issue=1;spage=53;epage=57;aulast=Munasingha https://doaj.org/toc/2352-4146 2352-4146 doi:10.4103/1995-7645.223561 https://doaj.org/article/0e609709671d48acba2b600af2c97af9 Asian Pacific Journal of Tropical Medicine, Vol 11, Iss 1, Pp 53-57 (2018) colombo district seroprevalencem sri lanka vaccine varicella Arctic medicine. Tropical medicine RC955-962 article 2018 ftdoajarticles https://doi.org/10.4103/1995-7645.223561 2022-12-31T01:25:13Z Objective: To determine the seroprevalence of varicella zoster virus (VZV) antibodies among the population residing in the Colombo district of Sri Lanka. Methods: A cross-sectional population-based study was conducted which included 1 258 participants. Blood samples were collected and questionnaires administered to obtain sociodemographic information and history of varicella and/or herpes zoster. Serum samples were assayed for VZV IgG antibodies using a commercial enzyme-linked immunosorbent assay kit. Results: Overall, the seroprevalence was 54.2% (95% CI = 51.5% 57.0%). Children below 1 year of age were seronegative, and only about 20.0% of children between 1 and 10 years of age were seropositive. Seropositivitiy increased with age and by the age of 40 years 74.3% were seropositive. Among women of childbearing age, the overall seroprevalence was about 62.0% (95% CI = 57.7%-66.1%) but was low 37.0% in the 15-19 age group. Conclusion In this population, 45.8% lacked natural immunity against varicella. Of women of childbearing age, 39.9% lacked immunity and in the subgroup of women 15-19 years of age, 63.0% women lacked immunity. In light of the country's success with the control and high coverage of other vaccine preventable diseases and that the vaccine is available in the private sector, the inclusion of varicella vaccine in the national immunization program may be considered. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Colombo ENVELOPE(-144.733,-144.733,-76.517,-76.517) Asian Pacific Journal of Tropical Medicine 11 1 53 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
colombo district seroprevalencem sri lanka vaccine varicella Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
colombo district seroprevalencem sri lanka vaccine varicella Arctic medicine. Tropical medicine RC955-962 Hathshya M Munasingha Ananda Amarasinghe Neelika G Malavige Nalini Sathiakumar Seroprevalence of varicella zoster virus in Colombo district, Sri Lanka |
topic_facet |
colombo district seroprevalencem sri lanka vaccine varicella Arctic medicine. Tropical medicine RC955-962 |
description |
Objective: To determine the seroprevalence of varicella zoster virus (VZV) antibodies among the population residing in the Colombo district of Sri Lanka. Methods: A cross-sectional population-based study was conducted which included 1 258 participants. Blood samples were collected and questionnaires administered to obtain sociodemographic information and history of varicella and/or herpes zoster. Serum samples were assayed for VZV IgG antibodies using a commercial enzyme-linked immunosorbent assay kit. Results: Overall, the seroprevalence was 54.2% (95% CI = 51.5% 57.0%). Children below 1 year of age were seronegative, and only about 20.0% of children between 1 and 10 years of age were seropositive. Seropositivitiy increased with age and by the age of 40 years 74.3% were seropositive. Among women of childbearing age, the overall seroprevalence was about 62.0% (95% CI = 57.7%-66.1%) but was low 37.0% in the 15-19 age group. Conclusion In this population, 45.8% lacked natural immunity against varicella. Of women of childbearing age, 39.9% lacked immunity and in the subgroup of women 15-19 years of age, 63.0% women lacked immunity. In light of the country's success with the control and high coverage of other vaccine preventable diseases and that the vaccine is available in the private sector, the inclusion of varicella vaccine in the national immunization program may be considered. |
format |
Article in Journal/Newspaper |
author |
Hathshya M Munasingha Ananda Amarasinghe Neelika G Malavige Nalini Sathiakumar |
author_facet |
Hathshya M Munasingha Ananda Amarasinghe Neelika G Malavige Nalini Sathiakumar |
author_sort |
Hathshya M Munasingha |
title |
Seroprevalence of varicella zoster virus in Colombo district, Sri Lanka |
title_short |
Seroprevalence of varicella zoster virus in Colombo district, Sri Lanka |
title_full |
Seroprevalence of varicella zoster virus in Colombo district, Sri Lanka |
title_fullStr |
Seroprevalence of varicella zoster virus in Colombo district, Sri Lanka |
title_full_unstemmed |
Seroprevalence of varicella zoster virus in Colombo district, Sri Lanka |
title_sort |
seroprevalence of varicella zoster virus in colombo district, sri lanka |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2018 |
url |
https://doi.org/10.4103/1995-7645.223561 https://doaj.org/article/0e609709671d48acba2b600af2c97af9 |
long_lat |
ENVELOPE(-144.733,-144.733,-76.517,-76.517) |
geographic |
Arctic Colombo |
geographic_facet |
Arctic Colombo |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Asian Pacific Journal of Tropical Medicine, Vol 11, Iss 1, Pp 53-57 (2018) |
op_relation |
http://www.apjtm.org/article.asp?issn=1995-7645;year=2018;volume=11;issue=1;spage=53;epage=57;aulast=Munasingha https://doaj.org/toc/2352-4146 2352-4146 doi:10.4103/1995-7645.223561 https://doaj.org/article/0e609709671d48acba2b600af2c97af9 |
op_doi |
https://doi.org/10.4103/1995-7645.223561 |
container_title |
Asian Pacific Journal of Tropical Medicine |
container_volume |
11 |
container_issue |
1 |
container_start_page |
53 |
_version_ |
1766340013399736320 |