Hepatocyte metaplasia in experimental chagasic pancreatitis: preliminary report

• Main Authors: Vitorino Modesto dos Santos, Marcus Aurelho de Lima, Marlene Cabrine-Santos, Daniela de Stefani Marquez, Eliane Lages-Silva, Jaqueline Maria Matheus, José Vitor de Oliveira Junior, Luis Eduardo Ramírez
• Format: Article in Journal/Newspaper
• Language: English
• Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2001
• Subjects: Hamster; Experimental Chagas' disease; Chronic pancreatitis; Oncocyte; Hepatocyte metaplasia; Arctic medicine. Tropical medicine; RC955-962; Arctic
• Online Access: https://doaj.org/article/0e537965fcf6411e8ec168ecbbf9f3b5

Beginning the study of chronic pathologic changes in pancreas of hamsters experimentally infected with Trypanosoma cruzi Vic strain, hepatocyte metaplasia was observed in one animal from infected group. This is the first report of oncocytes in Chagas' disease, which could be due to aberrant regenerative response to pancreas inflammatory process.