Human fusariosis: An emerging infection that is difficult to treat

• Published in: Revista da Sociedade Brasileira de Medicina Tropical
• Main Authors: Bruna Gerardon Batista, Magda Antunes de Chaves, Paula Reginatto, Otávio Jaconi Saraiva, Alexandre Meneghello Fuentefria
• Format: Article in Journal/Newspaper
• Language: English
• Published: Sociedade Brasileira de Medicina Tropical (SBMT)
• Subjects: fusarium spp; emerging fungal infection; human fusariosis; Arctic medicine. Tropical medicine; RC955-962; Arctic
• Online Access: https://doi.org/10.1590/0037-8682-0013-2020; https://doaj.org/article/0d2573ec302448429e091aeaedadfd9e

Abstract Fusarium spp. has been associated with a broad spectrum of emerging infections collectively termed fusariosis. This review includes articles published between 2005 and 2018 that describe the characteristics, clinical management, incidence, and emergence of these fungal infections. Fusarium solani and F. oxysporum are globally distributed and represent the most common complexes. Few therapeutic options exist due to intrinsic resistance, especially for the treatment of invasive fusariosis. Therefore, the use of drug combinations could be an important alternative for systemic antifungal resistance. Increase in the number of case reports on invasive fusariosis between 2005 and 2018 is evidence of the emergence of this fungal infection.