No evidence of increasing Haemophilus influenzae non-b infection in Australian Aboriginal children
Background. High, or increasing, rates of invasive Haemophilus influenzae (Hi) type a disease have been reported from North American native children from circumpolar regions, raising the question of serotype replacement being driven by vaccination against Hi type b (Hib). Indigenous Australians from...
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2013
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Online Access: | https://doi.org/10.3402/ijch.v72i0.20992 https://doaj.org/article/0c8a6c398127461ba4ff926dd060de74 |
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ftdoajarticles:oai:doaj.org/article:0c8a6c398127461ba4ff926dd060de74 2023-05-15T15:01:54+02:00 No evidence of increasing Haemophilus influenzae non-b infection in Australian Aboriginal children Robert I. Menzies Peter Markey Rowena Boyd Ann P. Koehler Peter B. McIntyre 2013-08-01T00:00:00Z https://doi.org/10.3402/ijch.v72i0.20992 https://doaj.org/article/0c8a6c398127461ba4ff926dd060de74 EN eng Taylor & Francis Group http://www.circumpolarhealthjournal.net/index.php/ijch/article/download/20992/pdf_1 https://doaj.org/toc/2242-3982 doi:10.3402/ijch.v72i0.20992 2242-3982 https://doaj.org/article/0c8a6c398127461ba4ff926dd060de74 International Journal of Circumpolar Health, Vol 72, Iss 0, Pp 1-6 (2013) Haemophilus influenza oceanic ancestry group epidemiology Arctic medicine. Tropical medicine RC955-962 article 2013 ftdoajarticles https://doi.org/10.3402/ijch.v72i0.20992 2022-12-31T04:38:29Z Background. High, or increasing, rates of invasive Haemophilus influenzae (Hi) type a disease have been reported from North American native children from circumpolar regions, raising the question of serotype replacement being driven by vaccination against Hi type b (Hib). Indigenous Australians from remote areas had high rates of invasive Hib disease in the past, comparable to those in North American Indigenous populations. Objective. Evaluate incidence rates of invasive Hi (overall and by serotype) in Indigenous Australian children over time. Design. Descriptive study of Hi incidence rates by serotype, in the Northern Territory (NT) and South Australia (SA) from 2001 to 2011. Comparison of NT data with a study that was conducted in the NT in 1985–1988, before Hib vaccine was introduced. Results. The average annual rate of invasive Hi type a (Hia) disease in Indigenous children aged <5 years was 11/100,000 population. Although the incidence of Hi infection in Indigenous children in 2001–2003 was lower than during 2004–2011, this may be due to changes in surveillance. No other trend over time in individual serotypes or total invasive Hi disease, in Indigenous or non-Indigenous people, was identified. Compared to 1985–1988, rates in 2001–2011 were lower in all serotype groupings, by 98% for Hib, 75% for Hia, 79% for other serotypes and 67% for non-typeable Hi. Conclusions. There is no evidence of increases in invasive disease due to Hia, other specific non-b types, or non-typeable Hi in Australian Indigenous children. These data suggest that the increase in Hia some time after the introduction of Hib vaccine, as seen in the North American Arctic Region, is not common to all populations with high pre-vaccine rates of invasive Hib disease. However, small case numbers and the lack of molecular subtyping and PCR confirmation of pre-vaccine results complicate comparisons with North American epidemiology. Article in Journal/Newspaper Arctic Circumpolar Health International Journal of Circumpolar Health Directory of Open Access Journals: DOAJ Articles Arctic International Journal of Circumpolar Health 72 1 20992 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Haemophilus influenza oceanic ancestry group epidemiology Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Haemophilus influenza oceanic ancestry group epidemiology Arctic medicine. Tropical medicine RC955-962 Robert I. Menzies Peter Markey Rowena Boyd Ann P. Koehler Peter B. McIntyre No evidence of increasing Haemophilus influenzae non-b infection in Australian Aboriginal children |
topic_facet |
Haemophilus influenza oceanic ancestry group epidemiology Arctic medicine. Tropical medicine RC955-962 |
description |
Background. High, or increasing, rates of invasive Haemophilus influenzae (Hi) type a disease have been reported from North American native children from circumpolar regions, raising the question of serotype replacement being driven by vaccination against Hi type b (Hib). Indigenous Australians from remote areas had high rates of invasive Hib disease in the past, comparable to those in North American Indigenous populations. Objective. Evaluate incidence rates of invasive Hi (overall and by serotype) in Indigenous Australian children over time. Design. Descriptive study of Hi incidence rates by serotype, in the Northern Territory (NT) and South Australia (SA) from 2001 to 2011. Comparison of NT data with a study that was conducted in the NT in 1985–1988, before Hib vaccine was introduced. Results. The average annual rate of invasive Hi type a (Hia) disease in Indigenous children aged <5 years was 11/100,000 population. Although the incidence of Hi infection in Indigenous children in 2001–2003 was lower than during 2004–2011, this may be due to changes in surveillance. No other trend over time in individual serotypes or total invasive Hi disease, in Indigenous or non-Indigenous people, was identified. Compared to 1985–1988, rates in 2001–2011 were lower in all serotype groupings, by 98% for Hib, 75% for Hia, 79% for other serotypes and 67% for non-typeable Hi. Conclusions. There is no evidence of increases in invasive disease due to Hia, other specific non-b types, or non-typeable Hi in Australian Indigenous children. These data suggest that the increase in Hia some time after the introduction of Hib vaccine, as seen in the North American Arctic Region, is not common to all populations with high pre-vaccine rates of invasive Hib disease. However, small case numbers and the lack of molecular subtyping and PCR confirmation of pre-vaccine results complicate comparisons with North American epidemiology. |
format |
Article in Journal/Newspaper |
author |
Robert I. Menzies Peter Markey Rowena Boyd Ann P. Koehler Peter B. McIntyre |
author_facet |
Robert I. Menzies Peter Markey Rowena Boyd Ann P. Koehler Peter B. McIntyre |
author_sort |
Robert I. Menzies |
title |
No evidence of increasing Haemophilus influenzae non-b infection in Australian Aboriginal children |
title_short |
No evidence of increasing Haemophilus influenzae non-b infection in Australian Aboriginal children |
title_full |
No evidence of increasing Haemophilus influenzae non-b infection in Australian Aboriginal children |
title_fullStr |
No evidence of increasing Haemophilus influenzae non-b infection in Australian Aboriginal children |
title_full_unstemmed |
No evidence of increasing Haemophilus influenzae non-b infection in Australian Aboriginal children |
title_sort |
no evidence of increasing haemophilus influenzae non-b infection in australian aboriginal children |
publisher |
Taylor & Francis Group |
publishDate |
2013 |
url |
https://doi.org/10.3402/ijch.v72i0.20992 https://doaj.org/article/0c8a6c398127461ba4ff926dd060de74 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic Circumpolar Health International Journal of Circumpolar Health |
genre_facet |
Arctic Circumpolar Health International Journal of Circumpolar Health |
op_source |
International Journal of Circumpolar Health, Vol 72, Iss 0, Pp 1-6 (2013) |
op_relation |
http://www.circumpolarhealthjournal.net/index.php/ijch/article/download/20992/pdf_1 https://doaj.org/toc/2242-3982 doi:10.3402/ijch.v72i0.20992 2242-3982 https://doaj.org/article/0c8a6c398127461ba4ff926dd060de74 |
op_doi |
https://doi.org/10.3402/ijch.v72i0.20992 |
container_title |
International Journal of Circumpolar Health |
container_volume |
72 |
container_issue |
1 |
container_start_page |
20992 |
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1766333905977212928 |