Vector competence of the tick Ixodes ricinus for transmission of Bartonella birtlesii.
Bartonella spp. are facultative intracellular vector-borne bacteria associated with several emerging diseases in humans and animals all over the world. The potential for involvement of ticks in transmission of Bartonella spp. has been heartily debated for many years. However, most of the data suppor...
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ftdoajarticles:oai:doaj.org/article:0bcbacc7bf6c4ec1b61858c35364b4e1 2023-05-15T15:09:38+02:00 Vector competence of the tick Ixodes ricinus for transmission of Bartonella birtlesii. Caroline Reis Martine Cote Danielle Le Rhun Benoit Lecuelle Michael L Levin Muriel Vayssier-Taussat Sarah I Bonnet 2011-01-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0001186 https://doaj.org/article/0bcbacc7bf6c4ec1b61858c35364b4e1 EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC3104967?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0001186 https://doaj.org/article/0bcbacc7bf6c4ec1b61858c35364b4e1 PLoS Neglected Tropical Diseases, Vol 5, Iss 5, p e1186 (2011) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2011 ftdoajarticles https://doi.org/10.1371/journal.pntd.0001186 2022-12-31T12:16:19Z Bartonella spp. are facultative intracellular vector-borne bacteria associated with several emerging diseases in humans and animals all over the world. The potential for involvement of ticks in transmission of Bartonella spp. has been heartily debated for many years. However, most of the data supporting bartonellae transmission by ticks come from molecular and serological epidemiological surveys in humans and animals providing only indirect evidences without a direct proof of tick vector competence for transmission of bartonellae. We used a murine model to assess the vector competence of Ixodes ricinus for Bartonella birtlesii. Larval and nymphal I. ricinus were fed on a B. birtlesii-infected mouse. The nymphs successfully transmitted B. birtlesii to naïve mice as bacteria were recovered from both the mouse blood and liver at seven and 16 days after tick bites. The female adults successfully emitted the bacteria into uninfected blood after three or more days of tick attachment, when fed via membrane feeding system. Histochemical staining showed the presence of bacteria in salivary glands and muscle tissues of partially engorged adult ticks, which had molted from the infected nymphs. These results confirm the vector competence of I. ricinus for B. birtlesii and represent the first in vivo demonstration of a Bartonella sp. transmission by ticks. Consequently, bartonelloses should be now included in the differential diagnosis for patients exposed to tick bites. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLoS Neglected Tropical Diseases 5 5 e1186 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Caroline Reis Martine Cote Danielle Le Rhun Benoit Lecuelle Michael L Levin Muriel Vayssier-Taussat Sarah I Bonnet Vector competence of the tick Ixodes ricinus for transmission of Bartonella birtlesii. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Bartonella spp. are facultative intracellular vector-borne bacteria associated with several emerging diseases in humans and animals all over the world. The potential for involvement of ticks in transmission of Bartonella spp. has been heartily debated for many years. However, most of the data supporting bartonellae transmission by ticks come from molecular and serological epidemiological surveys in humans and animals providing only indirect evidences without a direct proof of tick vector competence for transmission of bartonellae. We used a murine model to assess the vector competence of Ixodes ricinus for Bartonella birtlesii. Larval and nymphal I. ricinus were fed on a B. birtlesii-infected mouse. The nymphs successfully transmitted B. birtlesii to naïve mice as bacteria were recovered from both the mouse blood and liver at seven and 16 days after tick bites. The female adults successfully emitted the bacteria into uninfected blood after three or more days of tick attachment, when fed via membrane feeding system. Histochemical staining showed the presence of bacteria in salivary glands and muscle tissues of partially engorged adult ticks, which had molted from the infected nymphs. These results confirm the vector competence of I. ricinus for B. birtlesii and represent the first in vivo demonstration of a Bartonella sp. transmission by ticks. Consequently, bartonelloses should be now included in the differential diagnosis for patients exposed to tick bites. |
format |
Article in Journal/Newspaper |
author |
Caroline Reis Martine Cote Danielle Le Rhun Benoit Lecuelle Michael L Levin Muriel Vayssier-Taussat Sarah I Bonnet |
author_facet |
Caroline Reis Martine Cote Danielle Le Rhun Benoit Lecuelle Michael L Levin Muriel Vayssier-Taussat Sarah I Bonnet |
author_sort |
Caroline Reis |
title |
Vector competence of the tick Ixodes ricinus for transmission of Bartonella birtlesii. |
title_short |
Vector competence of the tick Ixodes ricinus for transmission of Bartonella birtlesii. |
title_full |
Vector competence of the tick Ixodes ricinus for transmission of Bartonella birtlesii. |
title_fullStr |
Vector competence of the tick Ixodes ricinus for transmission of Bartonella birtlesii. |
title_full_unstemmed |
Vector competence of the tick Ixodes ricinus for transmission of Bartonella birtlesii. |
title_sort |
vector competence of the tick ixodes ricinus for transmission of bartonella birtlesii. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2011 |
url |
https://doi.org/10.1371/journal.pntd.0001186 https://doaj.org/article/0bcbacc7bf6c4ec1b61858c35364b4e1 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 5, Iss 5, p e1186 (2011) |
op_relation |
http://europepmc.org/articles/PMC3104967?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0001186 https://doaj.org/article/0bcbacc7bf6c4ec1b61858c35364b4e1 |
op_doi |
https://doi.org/10.1371/journal.pntd.0001186 |
container_title |
PLoS Neglected Tropical Diseases |
container_volume |
5 |
container_issue |
5 |
container_start_page |
e1186 |
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1766340793766772736 |