Role of toll like-receptor 2 in inflammatory activity of macrophage infected with a recombinant BCG expressing the C-terminus of merozoite surface protein-1 of Plasmodium falciparum

• Published in: Asian Pacific Journal of Tropical Biomedicine
• Main Authors: Nor Munirah Zakaria, Rapeah Suppian, Norazmi Mohd Nor, Nor Fazila Che Mat
• Format: Article in Journal/Newspaper
• Language: English
• Published: Wolters Kluwer Medknow Publications 2018
• Subjects: macrophages; mycobacterium bovis bacillus calmette-guerin; plasmodium falciparum; proinflammatory cytokine; toll-like receptor 2; Arctic medicine. Tropical medicine; RC955-962; Biology (General); QH301-705.5; Arctic; Calmette
• Online Access: https://doi.org/10.4103/2221-1691.237075; https://doaj.org/article/09de0349b4c74829a665291fe81254c0

Objective: To investigate the role of toll-like receptor 2 (TLR2) in inflammatory activity of macrophage infected with the recombinant Mycobacterium bovis bacillus Calmette-Guerin (rBCG). Methods: Mouse macrophage cell line J774A.1 was infected with Mycobacterium bovis bacillus Calmette-Guerin (BCG)...