Economic and disease burden of dengue in Mexico.
BACKGROUND:Dengue imposes a substantial economic and disease burden in most tropical and subtropical countries. Dengue incidence and severity have dramatically increased in Mexico during the past decades. Having objective and comparable estimates of the economic burden of dengue is essential to info...
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ftdoajarticles:oai:doaj.org/article:0962018c56d045ac8b425308b9f3d2c9 2023-05-15T15:16:22+02:00 Economic and disease burden of dengue in Mexico. Eduardo A Undurraga Miguel Betancourt-Cravioto José Ramos-Castañeda Ruth Martínez-Vega Jorge Méndez-Galván Duane J Gubler María G Guzmán Scott B Halstead Eva Harris Pablo Kuri-Morales Roberto Tapia-Conyer Donald S Shepard 2015-03-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0003547 https://doaj.org/article/0962018c56d045ac8b425308b9f3d2c9 EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC4364886?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0003547 https://doaj.org/article/0962018c56d045ac8b425308b9f3d2c9 PLoS Neglected Tropical Diseases, Vol 9, Iss 3, p e0003547 (2015) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2015 ftdoajarticles https://doi.org/10.1371/journal.pntd.0003547 2022-12-31T04:12:31Z BACKGROUND:Dengue imposes a substantial economic and disease burden in most tropical and subtropical countries. Dengue incidence and severity have dramatically increased in Mexico during the past decades. Having objective and comparable estimates of the economic burden of dengue is essential to inform health policy, increase disease awareness, and assess the impact of dengue prevention and control technologies. METHODS AND FINDINGS:We estimated the annual economic and disease burden of dengue in Mexico for the years 2010-2011. We merged multiple data sources, including a prospective cohort study; patient interviews and macro-costing from major hospitals; surveillance, budget, and health data from the Ministry of Health; WHO cost estimates; and available literature. We conducted a probabilistic sensitivity analysis using Monte Carlo simulations to derive 95% certainty levels (CL) for our estimates. Results suggest that Mexico had about 139,000 (95%CL: 128,000-253,000) symptomatic and 119 (95%CL: 75-171) fatal dengue episodes annually on average (2010-2011), compared to an average of 30,941 symptomatic and 59 fatal dengue episodes reported. The annual cost, including surveillance and vector control, was US$170 (95%CL: 151-292) million, or $1.56 (95%CL: 1.38-2.68) per capita, comparable to other countries in the region. Of this, $87 (95%CL: 87-209) million or $0.80 per capita (95%CL: 0.62-1.12) corresponds to illness. Annual disease burden averaged 65 (95%CL: 36-99) disability-adjusted life years (DALYs) per million population. Inclusion of long-term sequelae, co-morbidities, impact on tourism, and health system disruption during outbreaks would further increase estimated economic and disease burden. CONCLUSION:With this study, Mexico joins Panama, Puerto Rico, Nicaragua, and Thailand as the only countries or areas worldwide with comprehensive (illness and preventive) empirical estimates of dengue burden. Burden varies annually; during an outbreak, dengue burden may be significantly higher than that of the ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 9 3 e0003547 |
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Directory of Open Access Journals: DOAJ Articles |
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English |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Eduardo A Undurraga Miguel Betancourt-Cravioto José Ramos-Castañeda Ruth Martínez-Vega Jorge Méndez-Galván Duane J Gubler María G Guzmán Scott B Halstead Eva Harris Pablo Kuri-Morales Roberto Tapia-Conyer Donald S Shepard Economic and disease burden of dengue in Mexico. |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
BACKGROUND:Dengue imposes a substantial economic and disease burden in most tropical and subtropical countries. Dengue incidence and severity have dramatically increased in Mexico during the past decades. Having objective and comparable estimates of the economic burden of dengue is essential to inform health policy, increase disease awareness, and assess the impact of dengue prevention and control technologies. METHODS AND FINDINGS:We estimated the annual economic and disease burden of dengue in Mexico for the years 2010-2011. We merged multiple data sources, including a prospective cohort study; patient interviews and macro-costing from major hospitals; surveillance, budget, and health data from the Ministry of Health; WHO cost estimates; and available literature. We conducted a probabilistic sensitivity analysis using Monte Carlo simulations to derive 95% certainty levels (CL) for our estimates. Results suggest that Mexico had about 139,000 (95%CL: 128,000-253,000) symptomatic and 119 (95%CL: 75-171) fatal dengue episodes annually on average (2010-2011), compared to an average of 30,941 symptomatic and 59 fatal dengue episodes reported. The annual cost, including surveillance and vector control, was US$170 (95%CL: 151-292) million, or $1.56 (95%CL: 1.38-2.68) per capita, comparable to other countries in the region. Of this, $87 (95%CL: 87-209) million or $0.80 per capita (95%CL: 0.62-1.12) corresponds to illness. Annual disease burden averaged 65 (95%CL: 36-99) disability-adjusted life years (DALYs) per million population. Inclusion of long-term sequelae, co-morbidities, impact on tourism, and health system disruption during outbreaks would further increase estimated economic and disease burden. CONCLUSION:With this study, Mexico joins Panama, Puerto Rico, Nicaragua, and Thailand as the only countries or areas worldwide with comprehensive (illness and preventive) empirical estimates of dengue burden. Burden varies annually; during an outbreak, dengue burden may be significantly higher than that of the ... |
format |
Article in Journal/Newspaper |
author |
Eduardo A Undurraga Miguel Betancourt-Cravioto José Ramos-Castañeda Ruth Martínez-Vega Jorge Méndez-Galván Duane J Gubler María G Guzmán Scott B Halstead Eva Harris Pablo Kuri-Morales Roberto Tapia-Conyer Donald S Shepard |
author_facet |
Eduardo A Undurraga Miguel Betancourt-Cravioto José Ramos-Castañeda Ruth Martínez-Vega Jorge Méndez-Galván Duane J Gubler María G Guzmán Scott B Halstead Eva Harris Pablo Kuri-Morales Roberto Tapia-Conyer Donald S Shepard |
author_sort |
Eduardo A Undurraga |
title |
Economic and disease burden of dengue in Mexico. |
title_short |
Economic and disease burden of dengue in Mexico. |
title_full |
Economic and disease burden of dengue in Mexico. |
title_fullStr |
Economic and disease burden of dengue in Mexico. |
title_full_unstemmed |
Economic and disease burden of dengue in Mexico. |
title_sort |
economic and disease burden of dengue in mexico. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2015 |
url |
https://doi.org/10.1371/journal.pntd.0003547 https://doaj.org/article/0962018c56d045ac8b425308b9f3d2c9 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 9, Iss 3, p e0003547 (2015) |
op_relation |
http://europepmc.org/articles/PMC4364886?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0003547 https://doaj.org/article/0962018c56d045ac8b425308b9f3d2c9 |
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https://doi.org/10.1371/journal.pntd.0003547 |
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PLOS Neglected Tropical Diseases |
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9 |
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3 |
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e0003547 |
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