First report of the aac(6’)-Ib-cr gene in Providencia stuartii isolates in Brazil

• Published in: Revista da Sociedade Brasileira de Medicina Tropical
• Main Authors: Sivoneide Maria da Silva, Bárbara de Azevedo Ramos, Ana Vitória Araújo Lima, Rafael Artur Cavalcanti Queiroz de Sá, Jailton Lobo da Costa Lima, Maria Amélia Vieira Maciel, Patrícia Maria Guedes Paiva, Márcia Vanusa da Silva, Maria Tereza dos Santos Correia, Maria Betânia Melo de Oliveira
• Format: Article in Journal/Newspaper
• Language: English
• Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2020
• Subjects: Antimicrobial agents; Enterobacteriaceae; MDR genes; Providencia stuartii; Arctic medicine. Tropical medicine; RC955-962; Arctic; Providencia
• Online Access: https://doi.org/10.1590/0037-8682-0524-2019; https://doaj.org/article/07e272d994174ba6bd7ee3152b7e4b26

Abstract INTRODUCTION: The aac(6’)-Ib-cr and bla KPC genes are spreading among Enterobacteriaceae species, including Providencia stuartii, in some countries of world. METHODS: These genes were investigated in 28 P. stuartii isolates from a public hospital in Recife, Pernambuco, Brazil, by PCR and sequencing. RESULTS: The aac(6’)-Ib-cr gene was detected in 16 resistant isolates, and the bla KPC gene was seen in 14. CONCLUSIONS: The presence of these genes in P. stuartii multi- and extensively drug-resistant isolates indicates that the resistance arsenal of this species is increasing, thus limiting the therapeutic options.