HPLC analysis and cell surface receptor binding activities of the crude aqueous and methanolic extract of Sesamum indicum

Objective: To identify the possible functional molecules for therapeutic uses by screening the crude aqueous and methanolic extracts derived from sesame seeds (Sesamum indicum) in vitro. Methods: High performance liquid chromatography was used to scan the functional molecules present in the extracts...

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Bibliographic Details
Published in:Asian Pacific Journal of Tropical Biomedicine
Main Authors: Repon Kumer Saha, Md. Abu Monsur Dinar, Kausain Akther Nabila, Priyanka Roy
Format: Article in Journal/Newspaper
Language:English
Published: Wolters Kluwer Medknow Publications 2014
Subjects:
Sesamum indicum
Hemagglutination
High performance liquid chromatography
Thin-layer chromatography
Arctic medicine. Tropical medicine
RC955-962
Biology (General)
QH301-705.5
Arctic
Online Access:https://doi.org/10.12980/APJTB.4.2014C973
https://doaj.org/article/07d65934cfbf421ba71f85bf8e3102dd
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Summary:Objective: To identify the possible functional molecules for therapeutic uses by screening the crude aqueous and methanolic extracts derived from sesame seeds (Sesamum indicum) in vitro. Methods: High performance liquid chromatography was used to scan the functional molecules present in the extracts. Results: The crude aqueous extracts showed the possibilities to present caffeine and cetirizine or its derivatives like molecules. On the other hand, the crude methanolic extract may contain Loratadine or its derivatives like molecules. Both type of extracts showed hemagglutination inhibition activities in all types of human blood samples tested. However, they showed stronger binding with AB+ blood group than those of A+ and B+ blood. Conclusions: Sesame seeds may be considered as a functional food.

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