Surveillance of Trypanosoma cruzi infection in Triatomine vectors, feral dogs and cats, and wild animals in and around El Paso county, Texas, and New Mexico.
The causative agent of Chagas disease, Trypanosoma cruzi, is transmitted by triatomine vectors. The insect is endemic in the Americas, including the United States, where epidemiological studies are limited, particularly in the Southwestern region. Here, we have determined the prevalence of T. cruzi...
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ftdoajarticles:oai:doaj.org/article:07af3acf675e4365a7848f0c0a3352c1 2023-05-15T15:09:22+02:00 Surveillance of Trypanosoma cruzi infection in Triatomine vectors, feral dogs and cats, and wild animals in and around El Paso county, Texas, and New Mexico. Felipe Rodriguez Brenda S Luna Olivia Calderon Claudia Manriquez-Roman Karsten Amezcua-Winter Jonathan Cedillo Rebeca Garcia-Vazquez Itzel A Tejeda Alvaro Romero Kenneth Waldrup Douglas M Watts Camilo Khatchikian Rosa A Maldonado 2021-02-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0009147 https://doaj.org/article/07af3acf675e4365a7848f0c0a3352c1 EN eng Public Library of Science (PLoS) https://doi.org/10.1371/journal.pntd.0009147 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0009147 https://doaj.org/article/07af3acf675e4365a7848f0c0a3352c1 PLoS Neglected Tropical Diseases, Vol 15, Iss 2, p e0009147 (2021) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2021 ftdoajarticles https://doi.org/10.1371/journal.pntd.0009147 2022-12-31T00:57:06Z The causative agent of Chagas disease, Trypanosoma cruzi, is transmitted by triatomine vectors. The insect is endemic in the Americas, including the United States, where epidemiological studies are limited, particularly in the Southwestern region. Here, we have determined the prevalence of T. cruzi in triatomines, feral cats and dogs, and wild animals, the infecting parasite genotypes and the mammalian host bloodmeal sources of the triatomines at four different geographical sites in the U.S.-Mexico border, including El Paso County, Texas, and nearby cities in New Mexico. Using qualitative polymerase chain reaction to detect T. cruzi infections, we found 66.4% (n = 225) of triatomines, 45.3% (n = 95) of feral dogs, 39.2% (n = 24) of feral cats, and 71.4% (n = 7) of wild animals positive for T. cruzi. Over 95% of T. cruzi genotypes or discrete typing units (DTUs) identified were TcI and some TcIV. Furthermore, Triatoma rubida was the triatomine species most frequently (98.2%) collected in all samples analyzed. These findings suggest a high prevalence of T. cruzi infections among triatomines, and feral and wild animals in the studied sites. Therefore, our results underscore the urgent need for implementation of a systematic epidemiological surveillance program for T. cruzi infections in insect vectors, and feral and wild animals, and Chagas disease in the human population in the southwestern region of the United States. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 15 2 e0009147 |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Felipe Rodriguez Brenda S Luna Olivia Calderon Claudia Manriquez-Roman Karsten Amezcua-Winter Jonathan Cedillo Rebeca Garcia-Vazquez Itzel A Tejeda Alvaro Romero Kenneth Waldrup Douglas M Watts Camilo Khatchikian Rosa A Maldonado Surveillance of Trypanosoma cruzi infection in Triatomine vectors, feral dogs and cats, and wild animals in and around El Paso county, Texas, and New Mexico. |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
The causative agent of Chagas disease, Trypanosoma cruzi, is transmitted by triatomine vectors. The insect is endemic in the Americas, including the United States, where epidemiological studies are limited, particularly in the Southwestern region. Here, we have determined the prevalence of T. cruzi in triatomines, feral cats and dogs, and wild animals, the infecting parasite genotypes and the mammalian host bloodmeal sources of the triatomines at four different geographical sites in the U.S.-Mexico border, including El Paso County, Texas, and nearby cities in New Mexico. Using qualitative polymerase chain reaction to detect T. cruzi infections, we found 66.4% (n = 225) of triatomines, 45.3% (n = 95) of feral dogs, 39.2% (n = 24) of feral cats, and 71.4% (n = 7) of wild animals positive for T. cruzi. Over 95% of T. cruzi genotypes or discrete typing units (DTUs) identified were TcI and some TcIV. Furthermore, Triatoma rubida was the triatomine species most frequently (98.2%) collected in all samples analyzed. These findings suggest a high prevalence of T. cruzi infections among triatomines, and feral and wild animals in the studied sites. Therefore, our results underscore the urgent need for implementation of a systematic epidemiological surveillance program for T. cruzi infections in insect vectors, and feral and wild animals, and Chagas disease in the human population in the southwestern region of the United States. |
format |
Article in Journal/Newspaper |
author |
Felipe Rodriguez Brenda S Luna Olivia Calderon Claudia Manriquez-Roman Karsten Amezcua-Winter Jonathan Cedillo Rebeca Garcia-Vazquez Itzel A Tejeda Alvaro Romero Kenneth Waldrup Douglas M Watts Camilo Khatchikian Rosa A Maldonado |
author_facet |
Felipe Rodriguez Brenda S Luna Olivia Calderon Claudia Manriquez-Roman Karsten Amezcua-Winter Jonathan Cedillo Rebeca Garcia-Vazquez Itzel A Tejeda Alvaro Romero Kenneth Waldrup Douglas M Watts Camilo Khatchikian Rosa A Maldonado |
author_sort |
Felipe Rodriguez |
title |
Surveillance of Trypanosoma cruzi infection in Triatomine vectors, feral dogs and cats, and wild animals in and around El Paso county, Texas, and New Mexico. |
title_short |
Surveillance of Trypanosoma cruzi infection in Triatomine vectors, feral dogs and cats, and wild animals in and around El Paso county, Texas, and New Mexico. |
title_full |
Surveillance of Trypanosoma cruzi infection in Triatomine vectors, feral dogs and cats, and wild animals in and around El Paso county, Texas, and New Mexico. |
title_fullStr |
Surveillance of Trypanosoma cruzi infection in Triatomine vectors, feral dogs and cats, and wild animals in and around El Paso county, Texas, and New Mexico. |
title_full_unstemmed |
Surveillance of Trypanosoma cruzi infection in Triatomine vectors, feral dogs and cats, and wild animals in and around El Paso county, Texas, and New Mexico. |
title_sort |
surveillance of trypanosoma cruzi infection in triatomine vectors, feral dogs and cats, and wild animals in and around el paso county, texas, and new mexico. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2021 |
url |
https://doi.org/10.1371/journal.pntd.0009147 https://doaj.org/article/07af3acf675e4365a7848f0c0a3352c1 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 15, Iss 2, p e0009147 (2021) |
op_relation |
https://doi.org/10.1371/journal.pntd.0009147 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0009147 https://doaj.org/article/07af3acf675e4365a7848f0c0a3352c1 |
op_doi |
https://doi.org/10.1371/journal.pntd.0009147 |
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PLOS Neglected Tropical Diseases |
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e0009147 |
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