Nocardiose pulmonar em paciente usuário crônico de corticóides Pulmonary nocardiosis in a patient who was a chronic corticosteroid user

• Published in: Revista da Sociedade Brasileira de Medicina Tropical
• Main Authors: Renata Maria Ferreira Brasileiro, André Carvalho Caribe de Araújo Pinho, Catarine Silva Medeiros, Francisco Ferri, Leonardo de Lucca Schiavon, Janaína Luz Narciso-Schiavon, Fernando Costa Buzzoleti
• Format: Article in Journal/Newspaper
• Language: English
• Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2007
• Subjects: Nocardiose; Púrpura trombocitopênica; Hospedeiro imunocomprometido; Pneumopatias; Nocardiosis; Thrombocytopenic purpura; Immunocompromised host; Lung diseases; Arctic medicine. Tropical medicine; RC955-962; Arctic; Aguda
• Online Access: https://doi.org/10.1590/S0037-86822007000500018; https://doaj.org/article/074de33f32e84e5996f107d5efcecffd

Nocardiose pulmonar é uma infecção grave e incomum causada pela Nocardia ssp, microorganismos que podem se comportar tanto como oportunistas quanto patógenos primários e que pode se apresentar como desordem aguda ou crônica supurativa. Relata-se o caso de um paciente de 49 anos, portador de púrpura trombocitopênica idiopática em tratamento com corticóides que desenvolveu infecção pulmonar por Nocardia farcinica, isolada em hemocultura. Apesar de tratamento correto com sulfametoxazol-trimetoprim, o paciente morreu após três meses de instituída terapia. Pulmonary nocardiosis is an infrequent and severe infection caused by Nocardia spp. These are microorganisms that may behave both as opportunists and as primary pathogens, and they may present as either acute or suppurative chronic disorders. We report on the case of a 49-year-old man with idiopathic thrombocytopenic purpura that was being treated with corticosteroids. He developed pulmonary infection due to Nocardia farcinica, which was isolated from blood cultures. Despite correct treatment with trimethoprim-sulfamethoxazole, the patient died three months after this therapy was instituted.