Night-shift work and hematological cancers: a population based case–control study in three Nordic countries
OBJECTIVE: The aim of this case–control study was to assess the effect of night-shift work on the risk of hematological cancers. METHODS: The study included 39 371 leukemia, 56 713 non-Hodgkin lymphoma, 9322 Hodgkin lymphoma, and 26 188 multiple myeloma cases diagnosed between 1961 and 2005 in Finla...
Published in: | Scandinavian Journal of Work, Environment & Health |
---|---|
Main Authors: | , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Nordic Association of Occupational Safety and Health (NOROSH)
2018
|
Subjects: | |
Online Access: | https://doi.org/10.5271/sjweh.3705 https://doaj.org/article/06b9e36456ff4a928c11f82a6b7cdc99 |
id |
ftdoajarticles:oai:doaj.org/article:06b9e36456ff4a928c11f82a6b7cdc99 |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:06b9e36456ff4a928c11f82a6b7cdc99 2023-05-15T16:50:51+02:00 Night-shift work and hematological cancers: a population based case–control study in three Nordic countries Madar Talibov Eero Pukkala Jan Ivar Martinsen Laufey Tryggvadottir Elisabete Weiderpass Johnni Hansen 2018-05-01T00:00:00Z https://doi.org/10.5271/sjweh.3705 https://doaj.org/article/06b9e36456ff4a928c11f82a6b7cdc99 EN eng Nordic Association of Occupational Safety and Health (NOROSH) https://www.sjweh.fi/show_abstract.php?abstract_id=3705 https://doaj.org/toc/0355-3140 https://doaj.org/toc/1795-990X 0355-3140 1795-990X doi:10.5271/sjweh.3705 https://doaj.org/article/06b9e36456ff4a928c11f82a6b7cdc99 Scandinavian Journal of Work, Environment & Health, Vol 44, Iss 3, Pp 258-264 (2018) jem night-shift work non-hodgkin lymphoma hodgkin lymphoma hematological cancer nordic multiple myeloma cancer leukemia job-exposure matrix shift work night work night worker shift worker case–control study circadian disruption Public aspects of medicine RA1-1270 article 2018 ftdoajarticles https://doi.org/10.5271/sjweh.3705 2022-12-31T05:36:03Z OBJECTIVE: The aim of this case–control study was to assess the effect of night-shift work on the risk of hematological cancers. METHODS: The study included 39 371 leukemia, 56 713 non-Hodgkin lymphoma, 9322 Hodgkin lymphoma, and 26 188 multiple myeloma cases diagnosed between 1961 and 2005 in Finland, Sweden, and Iceland. Five controls for each case were selected from the Nordic Occupational Cancer Study (NOCCA) cohort, matched by year of birth, sex and country. Night-shift exposure was assessed by using the NOCCA job-exposure matrix (JEM). Odds ratios (OR) and 95% confidence intervals (95% CI) were calculated from conditional logistic regression models. RESULTS: Overall, night work was not associated with a risk of hematological cancers. We observed a small but non-significantly increased risk for leukemia (OR 1.07, 95% CI 0.99–1.16), especially for acute myeloid leukemia (OR 1.15, 95% CI 0.97–1.36) among workers exposed to a high level of cumulative night work exposure. Night work exposure was not associated with lymphatic cancers and multiple myeloma. CONCLUSION: This study did not support associations between night-shift work and hematological cancers. Article in Journal/Newspaper Iceland Directory of Open Access Journals: DOAJ Articles Scandinavian Journal of Work, Environment & Health 44 3 258 264 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
jem night-shift work non-hodgkin lymphoma hodgkin lymphoma hematological cancer nordic multiple myeloma cancer leukemia job-exposure matrix shift work night work night worker shift worker case–control study circadian disruption Public aspects of medicine RA1-1270 |
spellingShingle |
jem night-shift work non-hodgkin lymphoma hodgkin lymphoma hematological cancer nordic multiple myeloma cancer leukemia job-exposure matrix shift work night work night worker shift worker case–control study circadian disruption Public aspects of medicine RA1-1270 Madar Talibov Eero Pukkala Jan Ivar Martinsen Laufey Tryggvadottir Elisabete Weiderpass Johnni Hansen Night-shift work and hematological cancers: a population based case–control study in three Nordic countries |
topic_facet |
jem night-shift work non-hodgkin lymphoma hodgkin lymphoma hematological cancer nordic multiple myeloma cancer leukemia job-exposure matrix shift work night work night worker shift worker case–control study circadian disruption Public aspects of medicine RA1-1270 |
description |
OBJECTIVE: The aim of this case–control study was to assess the effect of night-shift work on the risk of hematological cancers. METHODS: The study included 39 371 leukemia, 56 713 non-Hodgkin lymphoma, 9322 Hodgkin lymphoma, and 26 188 multiple myeloma cases diagnosed between 1961 and 2005 in Finland, Sweden, and Iceland. Five controls for each case were selected from the Nordic Occupational Cancer Study (NOCCA) cohort, matched by year of birth, sex and country. Night-shift exposure was assessed by using the NOCCA job-exposure matrix (JEM). Odds ratios (OR) and 95% confidence intervals (95% CI) were calculated from conditional logistic regression models. RESULTS: Overall, night work was not associated with a risk of hematological cancers. We observed a small but non-significantly increased risk for leukemia (OR 1.07, 95% CI 0.99–1.16), especially for acute myeloid leukemia (OR 1.15, 95% CI 0.97–1.36) among workers exposed to a high level of cumulative night work exposure. Night work exposure was not associated with lymphatic cancers and multiple myeloma. CONCLUSION: This study did not support associations between night-shift work and hematological cancers. |
format |
Article in Journal/Newspaper |
author |
Madar Talibov Eero Pukkala Jan Ivar Martinsen Laufey Tryggvadottir Elisabete Weiderpass Johnni Hansen |
author_facet |
Madar Talibov Eero Pukkala Jan Ivar Martinsen Laufey Tryggvadottir Elisabete Weiderpass Johnni Hansen |
author_sort |
Madar Talibov |
title |
Night-shift work and hematological cancers: a population based case–control study in three Nordic countries |
title_short |
Night-shift work and hematological cancers: a population based case–control study in three Nordic countries |
title_full |
Night-shift work and hematological cancers: a population based case–control study in three Nordic countries |
title_fullStr |
Night-shift work and hematological cancers: a population based case–control study in three Nordic countries |
title_full_unstemmed |
Night-shift work and hematological cancers: a population based case–control study in three Nordic countries |
title_sort |
night-shift work and hematological cancers: a population based case–control study in three nordic countries |
publisher |
Nordic Association of Occupational Safety and Health (NOROSH) |
publishDate |
2018 |
url |
https://doi.org/10.5271/sjweh.3705 https://doaj.org/article/06b9e36456ff4a928c11f82a6b7cdc99 |
genre |
Iceland |
genre_facet |
Iceland |
op_source |
Scandinavian Journal of Work, Environment & Health, Vol 44, Iss 3, Pp 258-264 (2018) |
op_relation |
https://www.sjweh.fi/show_abstract.php?abstract_id=3705 https://doaj.org/toc/0355-3140 https://doaj.org/toc/1795-990X 0355-3140 1795-990X doi:10.5271/sjweh.3705 https://doaj.org/article/06b9e36456ff4a928c11f82a6b7cdc99 |
op_doi |
https://doi.org/10.5271/sjweh.3705 |
container_title |
Scandinavian Journal of Work, Environment & Health |
container_volume |
44 |
container_issue |
3 |
container_start_page |
258 |
op_container_end_page |
264 |
_version_ |
1766040966552092672 |