Epidemiological and ecological aspects related to malaria in the area of influence of the lake at Porto Primavera dam, in western São Paulo State, Brazil Aspectos epidemiológicos e ecológicos relacionados à malária na área de influência do lago da Represa de Porto Primavera, região oeste do Estado de São Paulo, Brasil
A study was carried out in the area of influence of the Porto Primavera Hydroelectric Power Station, in western São Paulo State, to investigate ecological and epidemiological aspects of malaria in the area and monitor the profile of the anopheline populations following the environmental changes brou...
Published in: | Revista do Instituto de Medicina Tropical de São Paulo |
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ftdoajarticles:oai:doaj.org/article:06a3044701ab4f119e5a21a1eaf6aca9 2024-09-09T19:28:40+00:00 Epidemiological and ecological aspects related to malaria in the area of influence of the lake at Porto Primavera dam, in western São Paulo State, Brazil Aspectos epidemiológicos e ecológicos relacionados à malária na área de influência do lago da Represa de Porto Primavera, região oeste do Estado de São Paulo, Brasil Almério de C. Gomes Marcia B. de Paula Ana Maria R. de C. Duarte Maura A. Lima Rosely dos S. Malafronte Luis F. Mucci Sabina Lea D. Gotlieb Delsio Natal 2008-10-01T00:00:00Z https://doi.org/10.1590/S0036-46652008000500008 https://doaj.org/article/06a3044701ab4f119e5a21a1eaf6aca9 EN eng Universidade de São Paulo (USP) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652008000500008 https://doaj.org/toc/0036-4665 https://doaj.org/toc/1678-9946 doi:10.1590/S0036-46652008000500008 0036-4665 1678-9946 https://doaj.org/article/06a3044701ab4f119e5a21a1eaf6aca9 Revista do Instituto de Medicina Tropical de São Paulo, Vol 50, Iss 5, Pp 287-295 (2008) Malaria Porto Primavera Hydroelectric Power Station Entomology Antibodies to Circumsporozoite Protein Antibodies to Plasmodium blood-stage antigens Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2008 ftdoajarticles https://doi.org/10.1590/S0036-46652008000500008 2024-08-05T17:49:30Z A study was carried out in the area of influence of the Porto Primavera Hydroelectric Power Station, in western São Paulo State, to investigate ecological and epidemiological aspects of malaria in the area and monitor the profile of the anopheline populations following the environmental changes brought about by the construction of the lake. Mosquitoes captured were analyzed by standardized indicator species analysis (ISA) before and during different flooding phases (253 m and 257 m elevations). The local human population was studied by means of parasitological (thin/thick blood smears), molecular (PCR) and serological tests. Serological tests consisted of Enzyme Linked Immunosorbent Assay (ELISA) with synthetic peptides of the circumsporozoite protein (CSP) from classic Plasmodium vivax, P. vivax variants (VK247 and "vivax-like"), P. malariae and P. falciparum and Indirect Immunofluorescence Assay (IFA) with asexual forms of P. vivax, P. malariae and P. falciparum. The results of the entomological survey indicated that, although the Anopheles darlingi population increased after the flooding, the population density remained very low. No malaria, parasite infection or DNA was detected in the inhabitants of the study area. However, there was a low frequency of antibodies against asexual forms and a significant prevalence of antibodies against P. vivax, P. vivax variants, P. falciparum and P. malariae; the presence of these antibodies may result from recent or less recent contact with human or simian Plasmodium (a parallel study in the same area revealed the existence of a sylvatic cycle). Nevertheless, these results suggest that, as in other places where malaria is present and potential vectors circulate, the local epidemiological conditions observed could potentially support the transmission of malaria in Porto Primavera Lake if infected individuals are introduced in sufficient numbers. Further studies are required to elucidate the phenomena described in this paper. Foi realizada pesquisa na área de influência do ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista do Instituto de Medicina Tropical de São Paulo 50 5 287 295 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Malaria Porto Primavera Hydroelectric Power Station Entomology Antibodies to Circumsporozoite Protein Antibodies to Plasmodium blood-stage antigens Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
spellingShingle |
Malaria Porto Primavera Hydroelectric Power Station Entomology Antibodies to Circumsporozoite Protein Antibodies to Plasmodium blood-stage antigens Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Almério de C. Gomes Marcia B. de Paula Ana Maria R. de C. Duarte Maura A. Lima Rosely dos S. Malafronte Luis F. Mucci Sabina Lea D. Gotlieb Delsio Natal Epidemiological and ecological aspects related to malaria in the area of influence of the lake at Porto Primavera dam, in western São Paulo State, Brazil Aspectos epidemiológicos e ecológicos relacionados à malária na área de influência do lago da Represa de Porto Primavera, região oeste do Estado de São Paulo, Brasil |
topic_facet |
Malaria Porto Primavera Hydroelectric Power Station Entomology Antibodies to Circumsporozoite Protein Antibodies to Plasmodium blood-stage antigens Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
A study was carried out in the area of influence of the Porto Primavera Hydroelectric Power Station, in western São Paulo State, to investigate ecological and epidemiological aspects of malaria in the area and monitor the profile of the anopheline populations following the environmental changes brought about by the construction of the lake. Mosquitoes captured were analyzed by standardized indicator species analysis (ISA) before and during different flooding phases (253 m and 257 m elevations). The local human population was studied by means of parasitological (thin/thick blood smears), molecular (PCR) and serological tests. Serological tests consisted of Enzyme Linked Immunosorbent Assay (ELISA) with synthetic peptides of the circumsporozoite protein (CSP) from classic Plasmodium vivax, P. vivax variants (VK247 and "vivax-like"), P. malariae and P. falciparum and Indirect Immunofluorescence Assay (IFA) with asexual forms of P. vivax, P. malariae and P. falciparum. The results of the entomological survey indicated that, although the Anopheles darlingi population increased after the flooding, the population density remained very low. No malaria, parasite infection or DNA was detected in the inhabitants of the study area. However, there was a low frequency of antibodies against asexual forms and a significant prevalence of antibodies against P. vivax, P. vivax variants, P. falciparum and P. malariae; the presence of these antibodies may result from recent or less recent contact with human or simian Plasmodium (a parallel study in the same area revealed the existence of a sylvatic cycle). Nevertheless, these results suggest that, as in other places where malaria is present and potential vectors circulate, the local epidemiological conditions observed could potentially support the transmission of malaria in Porto Primavera Lake if infected individuals are introduced in sufficient numbers. Further studies are required to elucidate the phenomena described in this paper. Foi realizada pesquisa na área de influência do ... |
format |
Article in Journal/Newspaper |
author |
Almério de C. Gomes Marcia B. de Paula Ana Maria R. de C. Duarte Maura A. Lima Rosely dos S. Malafronte Luis F. Mucci Sabina Lea D. Gotlieb Delsio Natal |
author_facet |
Almério de C. Gomes Marcia B. de Paula Ana Maria R. de C. Duarte Maura A. Lima Rosely dos S. Malafronte Luis F. Mucci Sabina Lea D. Gotlieb Delsio Natal |
author_sort |
Almério de C. Gomes |
title |
Epidemiological and ecological aspects related to malaria in the area of influence of the lake at Porto Primavera dam, in western São Paulo State, Brazil Aspectos epidemiológicos e ecológicos relacionados à malária na área de influência do lago da Represa de Porto Primavera, região oeste do Estado de São Paulo, Brasil |
title_short |
Epidemiological and ecological aspects related to malaria in the area of influence of the lake at Porto Primavera dam, in western São Paulo State, Brazil Aspectos epidemiológicos e ecológicos relacionados à malária na área de influência do lago da Represa de Porto Primavera, região oeste do Estado de São Paulo, Brasil |
title_full |
Epidemiological and ecological aspects related to malaria in the area of influence of the lake at Porto Primavera dam, in western São Paulo State, Brazil Aspectos epidemiológicos e ecológicos relacionados à malária na área de influência do lago da Represa de Porto Primavera, região oeste do Estado de São Paulo, Brasil |
title_fullStr |
Epidemiological and ecological aspects related to malaria in the area of influence of the lake at Porto Primavera dam, in western São Paulo State, Brazil Aspectos epidemiológicos e ecológicos relacionados à malária na área de influência do lago da Represa de Porto Primavera, região oeste do Estado de São Paulo, Brasil |
title_full_unstemmed |
Epidemiological and ecological aspects related to malaria in the area of influence of the lake at Porto Primavera dam, in western São Paulo State, Brazil Aspectos epidemiológicos e ecológicos relacionados à malária na área de influência do lago da Represa de Porto Primavera, região oeste do Estado de São Paulo, Brasil |
title_sort |
epidemiological and ecological aspects related to malaria in the area of influence of the lake at porto primavera dam, in western são paulo state, brazil aspectos epidemiológicos e ecológicos relacionados à malária na área de influência do lago da represa de porto primavera, região oeste do estado de são paulo, brasil |
publisher |
Universidade de São Paulo (USP) |
publishDate |
2008 |
url |
https://doi.org/10.1590/S0036-46652008000500008 https://doaj.org/article/06a3044701ab4f119e5a21a1eaf6aca9 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista do Instituto de Medicina Tropical de São Paulo, Vol 50, Iss 5, Pp 287-295 (2008) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652008000500008 https://doaj.org/toc/0036-4665 https://doaj.org/toc/1678-9946 doi:10.1590/S0036-46652008000500008 0036-4665 1678-9946 https://doaj.org/article/06a3044701ab4f119e5a21a1eaf6aca9 |
op_doi |
https://doi.org/10.1590/S0036-46652008000500008 |
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