Cugini's syndrome: its clinical history and diagnosis
INTRODUCTION: This article deals with the description and diagnosis of a new nosographic syndrome, which received the eponym of "Cugini's syndrome" by the name of the Author who discovered its clinical picture. This syndrome is characterized by the binomial: "minimal target organ...
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ftdoajarticles:oai:doaj.org/article:05fc2b6a7ac84496813f941ce5f065ce 2023-05-15T16:02:06+02:00 Cugini's syndrome: its clinical history and diagnosis Laura Gasbarrone 2013-09-01T00:00:00Z https://doi.org/10.4415/ANN_13_03_13 https://doaj.org/article/05fc2b6a7ac84496813f941ce5f065ce EN eng Istituto Superiore di Sanità http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0021-25712013000300013&lng=en&tlng=en https://doaj.org/toc/0021-2571 0021-2571 doi:10.4415/ANN_13_03_13 https://doaj.org/article/05fc2b6a7ac84496813f941ce5f065ce Annali dell'Istituto Superiore di Sanità, Vol 49, Iss 3, Pp 309-312 (2013) blood pressure ABPM ABPM-diagnosable prehypertension monitoring prehypertension masked prehypertension normotension hypertension Public aspects of medicine RA1-1270 article 2013 ftdoajarticles https://doi.org/10.4415/ANN_13_03_13 2022-12-31T12:33:06Z INTRODUCTION: This article deals with the description and diagnosis of a new nosographic syndrome, which received the eponym of "Cugini's syndrome" by the name of the Author who discovered its clinical picture. This syndrome is characterized by the binomial: "minimal target organ damage associated to monitoring prehypertension". CLINICAL HISTORY AND DIAGNOSIS: Between the years 1997 and 2002, the Author published a series of investigations regarding some office normotensives who inexplicably showed incipient signs of target organ damage (TOD). Investigated via ambulatory (A) blood (B) pressure (P) monitoring (M), these subjects were surprisingly found not to be hypertensive. Neverthless, the office normotensives with TOD exibited the daily mean level of their systolic (S) and diastolic (D) BP (DML SBP/DBP) significantly more elevated as compared to true normotensives. Because of these ABPM findings, the Author realized that the investigated subjects were false normotensives whose TOD was associated with a monitoring prehypertension (ABPM-diagnosable prehypertension alias monitoring prehypertension alias masked prehypertension). The year after the last Cugini's investigation, the INC-7 Reports introduced the term: "prehypertension" in its classification of arterial hypertension, as an office sphygmomanometric condition in between office normotension and office hypertension. The ABPM cut-off upper limits for a differential diagnosis between monitoring normotension, prehypertension and hypertension are reported, as calculated by the Author in its collection of ABPMs. The eponym of "Cugini's syndrome" was assigned in 2007 and confirmed in 2009. CONCLUSIVE REMARKS: The monitoring prehypertension is a further condition of discrepancy between office sphygmomanometry and ABPM, as per a masked prehypertension, whose diagnosis has to be immediately diagnosed, for preventing the onset of a TOD. There are reported the present investigations dealing with the possible need for an early antihypertensive treatment of ... Article in Journal/Newspaper DML Directory of Open Access Journals: DOAJ Articles |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
blood pressure ABPM ABPM-diagnosable prehypertension monitoring prehypertension masked prehypertension normotension hypertension Public aspects of medicine RA1-1270 |
spellingShingle |
blood pressure ABPM ABPM-diagnosable prehypertension monitoring prehypertension masked prehypertension normotension hypertension Public aspects of medicine RA1-1270 Laura Gasbarrone Cugini's syndrome: its clinical history and diagnosis |
topic_facet |
blood pressure ABPM ABPM-diagnosable prehypertension monitoring prehypertension masked prehypertension normotension hypertension Public aspects of medicine RA1-1270 |
description |
INTRODUCTION: This article deals with the description and diagnosis of a new nosographic syndrome, which received the eponym of "Cugini's syndrome" by the name of the Author who discovered its clinical picture. This syndrome is characterized by the binomial: "minimal target organ damage associated to monitoring prehypertension". CLINICAL HISTORY AND DIAGNOSIS: Between the years 1997 and 2002, the Author published a series of investigations regarding some office normotensives who inexplicably showed incipient signs of target organ damage (TOD). Investigated via ambulatory (A) blood (B) pressure (P) monitoring (M), these subjects were surprisingly found not to be hypertensive. Neverthless, the office normotensives with TOD exibited the daily mean level of their systolic (S) and diastolic (D) BP (DML SBP/DBP) significantly more elevated as compared to true normotensives. Because of these ABPM findings, the Author realized that the investigated subjects were false normotensives whose TOD was associated with a monitoring prehypertension (ABPM-diagnosable prehypertension alias monitoring prehypertension alias masked prehypertension). The year after the last Cugini's investigation, the INC-7 Reports introduced the term: "prehypertension" in its classification of arterial hypertension, as an office sphygmomanometric condition in between office normotension and office hypertension. The ABPM cut-off upper limits for a differential diagnosis between monitoring normotension, prehypertension and hypertension are reported, as calculated by the Author in its collection of ABPMs. The eponym of "Cugini's syndrome" was assigned in 2007 and confirmed in 2009. CONCLUSIVE REMARKS: The monitoring prehypertension is a further condition of discrepancy between office sphygmomanometry and ABPM, as per a masked prehypertension, whose diagnosis has to be immediately diagnosed, for preventing the onset of a TOD. There are reported the present investigations dealing with the possible need for an early antihypertensive treatment of ... |
format |
Article in Journal/Newspaper |
author |
Laura Gasbarrone |
author_facet |
Laura Gasbarrone |
author_sort |
Laura Gasbarrone |
title |
Cugini's syndrome: its clinical history and diagnosis |
title_short |
Cugini's syndrome: its clinical history and diagnosis |
title_full |
Cugini's syndrome: its clinical history and diagnosis |
title_fullStr |
Cugini's syndrome: its clinical history and diagnosis |
title_full_unstemmed |
Cugini's syndrome: its clinical history and diagnosis |
title_sort |
cugini's syndrome: its clinical history and diagnosis |
publisher |
Istituto Superiore di Sanità |
publishDate |
2013 |
url |
https://doi.org/10.4415/ANN_13_03_13 https://doaj.org/article/05fc2b6a7ac84496813f941ce5f065ce |
genre |
DML |
genre_facet |
DML |
op_source |
Annali dell'Istituto Superiore di Sanità, Vol 49, Iss 3, Pp 309-312 (2013) |
op_relation |
http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0021-25712013000300013&lng=en&tlng=en https://doaj.org/toc/0021-2571 0021-2571 doi:10.4415/ANN_13_03_13 https://doaj.org/article/05fc2b6a7ac84496813f941ce5f065ce |
op_doi |
https://doi.org/10.4415/ANN_13_03_13 |
_version_ |
1766397710231928832 |