Pre-elimination of malaria on the island of Príncipe
Abstract Background Plasmodium falciparum is the major species responsible for malaria transmission on the island of Príncipe, in the Republic of São Tomé and Príncipe (STP). Indoor residual spraying (IRS) has been intensively deployed on the island, since 2003. Other measures included intermittent...
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ftdoajarticles:oai:doaj.org/article:05cbe23a4dc348d5bf5d56c43e235789 2023-05-15T15:17:07+02:00 Pre-elimination of malaria on the island of Príncipe do Rosario Virgilio E Rampao Herodes Liu Chia-Tai Lee Pei-Wen Shaio Men-Fang 2010-01-01T00:00:00Z https://doi.org/10.1186/1475-2875-9-26 https://doaj.org/article/05cbe23a4dc348d5bf5d56c43e235789 EN eng BMC http://www.malariajournal.com/content/9/1/26 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-9-26 1475-2875 https://doaj.org/article/05cbe23a4dc348d5bf5d56c43e235789 Malaria Journal, Vol 9, Iss 1, p 26 (2010) Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2010 ftdoajarticles https://doi.org/10.1186/1475-2875-9-26 2022-12-30T23:47:33Z Abstract Background Plasmodium falciparum is the major species responsible for malaria transmission on the island of Príncipe, in the Republic of São Tomé and Príncipe (STP). Indoor residual spraying (IRS) has been intensively deployed on the island, since 2003. Other measures included intermittent preventive therapy (IPT), since 2004, as well as artemisinin-based therapy (ACT) and long-lasting insecticidal nets (LLINs) from 2005. The work was coordinated by the Ministry of Health of STP through their Centro Nacional de Endemias (CNE) and the impact of such an integrated control programme on the prevalence and epidemiology of malaria in Príncipe was evaluated. Methods The scaling-up of preventive strategies included IRS, LLINs, IPT for pregnant women, as well as early diagnosis and prompt treatment with ACT. Regular implementation of an island-wide IRS programme was carried out yearly in 2003-2005, and later in 2008. Malaria incidence and prevalence were estimated based on passive case detection and active case detection, respectively. Slide positivity rate (SPR) was used as an indicator of any increase of malaria cases during and after the control programme was initiated. Results Regular IRS achieved a coverage of 85-90% for each of the four annual cycles (2003-2005, annually and one spraying in 2008) while usage of LLINs was never superior to 50% from 2006-2009. Coverage of IPT steadily increased from 50% in 2004 to 80% in 2008. Since 2006, over 90% of uncomplicated malaria patients received ACT treatment. Severe malaria cases were hospitalized and treated with quinine. Monthly trends of SPR were constantly over 50% in 2003, but steadily decreased below 10% in 2006. SPR has been below 5% since 2007, but an increase to up to 15% was noted in June 2009 when 16 imported cases were detected. A steep decline by 99% of malaria incidence was observed between 2003 and 2008, with an incidence risk of the population of five per thousand, in 2008. No malaria mortality has been reported since 2005. Species shift from ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Malaria Journal 9 1 26 |
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Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
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Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 do Rosario Virgilio E Rampao Herodes Liu Chia-Tai Lee Pei-Wen Shaio Men-Fang Pre-elimination of malaria on the island of Príncipe |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Background Plasmodium falciparum is the major species responsible for malaria transmission on the island of Príncipe, in the Republic of São Tomé and Príncipe (STP). Indoor residual spraying (IRS) has been intensively deployed on the island, since 2003. Other measures included intermittent preventive therapy (IPT), since 2004, as well as artemisinin-based therapy (ACT) and long-lasting insecticidal nets (LLINs) from 2005. The work was coordinated by the Ministry of Health of STP through their Centro Nacional de Endemias (CNE) and the impact of such an integrated control programme on the prevalence and epidemiology of malaria in Príncipe was evaluated. Methods The scaling-up of preventive strategies included IRS, LLINs, IPT for pregnant women, as well as early diagnosis and prompt treatment with ACT. Regular implementation of an island-wide IRS programme was carried out yearly in 2003-2005, and later in 2008. Malaria incidence and prevalence were estimated based on passive case detection and active case detection, respectively. Slide positivity rate (SPR) was used as an indicator of any increase of malaria cases during and after the control programme was initiated. Results Regular IRS achieved a coverage of 85-90% for each of the four annual cycles (2003-2005, annually and one spraying in 2008) while usage of LLINs was never superior to 50% from 2006-2009. Coverage of IPT steadily increased from 50% in 2004 to 80% in 2008. Since 2006, over 90% of uncomplicated malaria patients received ACT treatment. Severe malaria cases were hospitalized and treated with quinine. Monthly trends of SPR were constantly over 50% in 2003, but steadily decreased below 10% in 2006. SPR has been below 5% since 2007, but an increase to up to 15% was noted in June 2009 when 16 imported cases were detected. A steep decline by 99% of malaria incidence was observed between 2003 and 2008, with an incidence risk of the population of five per thousand, in 2008. No malaria mortality has been reported since 2005. Species shift from ... |
format |
Article in Journal/Newspaper |
author |
do Rosario Virgilio E Rampao Herodes Liu Chia-Tai Lee Pei-Wen Shaio Men-Fang |
author_facet |
do Rosario Virgilio E Rampao Herodes Liu Chia-Tai Lee Pei-Wen Shaio Men-Fang |
author_sort |
do Rosario Virgilio E |
title |
Pre-elimination of malaria on the island of Príncipe |
title_short |
Pre-elimination of malaria on the island of Príncipe |
title_full |
Pre-elimination of malaria on the island of Príncipe |
title_fullStr |
Pre-elimination of malaria on the island of Príncipe |
title_full_unstemmed |
Pre-elimination of malaria on the island of Príncipe |
title_sort |
pre-elimination of malaria on the island of príncipe |
publisher |
BMC |
publishDate |
2010 |
url |
https://doi.org/10.1186/1475-2875-9-26 https://doaj.org/article/05cbe23a4dc348d5bf5d56c43e235789 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 9, Iss 1, p 26 (2010) |
op_relation |
http://www.malariajournal.com/content/9/1/26 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-9-26 1475-2875 https://doaj.org/article/05cbe23a4dc348d5bf5d56c43e235789 |
op_doi |
https://doi.org/10.1186/1475-2875-9-26 |
container_title |
Malaria Journal |
container_volume |
9 |
container_issue |
1 |
container_start_page |
26 |
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1766347398270943232 |