Possible high risk of transmission of the Nipah virus in South and South East Asia: a review
Abstract Nipah virus (NiV) is a zoonotic, single-stranded RNA virus from the family Paramyxoviridae, genus Henipavirus. NiV is a biosafety-level-4 pathogen that is mostly spread by Pteropus species, which serve as its natural reservoir host. NiV is one of the major public health challenges in South...
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ftdoajarticles:oai:doaj.org/article:05623df5db094a71ba95665401782fd5 2023-09-05T13:17:26+02:00 Possible high risk of transmission of the Nipah virus in South and South East Asia: a review Jagadish Joshi Yogendra Shah Kishor Pandey Ram Prashad Ojha Chet Raj Joshi Lok Raj Bhatt Shyam Prakash Dumre Pushpa Raj Acharya Hem Raj Joshi Shikha Rimal Ramesh Shahi Deepak Pokharel Kamal Singh Khadka Bimal Dahal Saroj Nepal Ram Singh Dhami Krishna Prasad Pant Rajdip Basnet Basu Dev Pandey 2023-08-01T00:00:00Z https://doi.org/10.1186/s41182-023-00535-7 https://doaj.org/article/05623df5db094a71ba95665401782fd5 EN eng BMC https://doi.org/10.1186/s41182-023-00535-7 https://doaj.org/toc/1349-4147 doi:10.1186/s41182-023-00535-7 1349-4147 https://doaj.org/article/05623df5db094a71ba95665401782fd5 Tropical Medicine and Health, Vol 51, Iss 1, Pp 1-8 (2023) Nipah virus Southeast Asia ELISA PCR One Health Arctic medicine. Tropical medicine RC955-962 article 2023 ftdoajarticles https://doi.org/10.1186/s41182-023-00535-7 2023-08-20T00:36:10Z Abstract Nipah virus (NiV) is a zoonotic, single-stranded RNA virus from the family Paramyxoviridae, genus Henipavirus. NiV is a biosafety-level-4 pathogen that is mostly spread by Pteropus species, which serve as its natural reservoir host. NiV is one of the major public health challenges in South and South East Asia. However, few molecular studies have been conducted to characterise NiV in a specific region. The main objective of this review is to understand the epidemiology, pathogenesis, molecular surveillance, transmission dynamics, genetic diversity, reservoir host, clinical characteristics, and phylogenetics of NiV. South and South East Asian nations have experienced NiV outbreaks. Phylogenetic analysis confirmed that two primary clades of NiV are in circulation. In humans, NiV causes severe respiratory illness and/or deadly encephalitis. NiV is mainly diagnosed by ELISA along with PCR. Therefore, we recommend that the governments of the region support the One Health approach to reducing the risk of zoonotic disease transmission in their respective countries. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Tropical Medicine and Health 51 1 |
institution |
Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Nipah virus Southeast Asia ELISA PCR One Health Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Nipah virus Southeast Asia ELISA PCR One Health Arctic medicine. Tropical medicine RC955-962 Jagadish Joshi Yogendra Shah Kishor Pandey Ram Prashad Ojha Chet Raj Joshi Lok Raj Bhatt Shyam Prakash Dumre Pushpa Raj Acharya Hem Raj Joshi Shikha Rimal Ramesh Shahi Deepak Pokharel Kamal Singh Khadka Bimal Dahal Saroj Nepal Ram Singh Dhami Krishna Prasad Pant Rajdip Basnet Basu Dev Pandey Possible high risk of transmission of the Nipah virus in South and South East Asia: a review |
topic_facet |
Nipah virus Southeast Asia ELISA PCR One Health Arctic medicine. Tropical medicine RC955-962 |
description |
Abstract Nipah virus (NiV) is a zoonotic, single-stranded RNA virus from the family Paramyxoviridae, genus Henipavirus. NiV is a biosafety-level-4 pathogen that is mostly spread by Pteropus species, which serve as its natural reservoir host. NiV is one of the major public health challenges in South and South East Asia. However, few molecular studies have been conducted to characterise NiV in a specific region. The main objective of this review is to understand the epidemiology, pathogenesis, molecular surveillance, transmission dynamics, genetic diversity, reservoir host, clinical characteristics, and phylogenetics of NiV. South and South East Asian nations have experienced NiV outbreaks. Phylogenetic analysis confirmed that two primary clades of NiV are in circulation. In humans, NiV causes severe respiratory illness and/or deadly encephalitis. NiV is mainly diagnosed by ELISA along with PCR. Therefore, we recommend that the governments of the region support the One Health approach to reducing the risk of zoonotic disease transmission in their respective countries. |
format |
Article in Journal/Newspaper |
author |
Jagadish Joshi Yogendra Shah Kishor Pandey Ram Prashad Ojha Chet Raj Joshi Lok Raj Bhatt Shyam Prakash Dumre Pushpa Raj Acharya Hem Raj Joshi Shikha Rimal Ramesh Shahi Deepak Pokharel Kamal Singh Khadka Bimal Dahal Saroj Nepal Ram Singh Dhami Krishna Prasad Pant Rajdip Basnet Basu Dev Pandey |
author_facet |
Jagadish Joshi Yogendra Shah Kishor Pandey Ram Prashad Ojha Chet Raj Joshi Lok Raj Bhatt Shyam Prakash Dumre Pushpa Raj Acharya Hem Raj Joshi Shikha Rimal Ramesh Shahi Deepak Pokharel Kamal Singh Khadka Bimal Dahal Saroj Nepal Ram Singh Dhami Krishna Prasad Pant Rajdip Basnet Basu Dev Pandey |
author_sort |
Jagadish Joshi |
title |
Possible high risk of transmission of the Nipah virus in South and South East Asia: a review |
title_short |
Possible high risk of transmission of the Nipah virus in South and South East Asia: a review |
title_full |
Possible high risk of transmission of the Nipah virus in South and South East Asia: a review |
title_fullStr |
Possible high risk of transmission of the Nipah virus in South and South East Asia: a review |
title_full_unstemmed |
Possible high risk of transmission of the Nipah virus in South and South East Asia: a review |
title_sort |
possible high risk of transmission of the nipah virus in south and south east asia: a review |
publisher |
BMC |
publishDate |
2023 |
url |
https://doi.org/10.1186/s41182-023-00535-7 https://doaj.org/article/05623df5db094a71ba95665401782fd5 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Tropical Medicine and Health, Vol 51, Iss 1, Pp 1-8 (2023) |
op_relation |
https://doi.org/10.1186/s41182-023-00535-7 https://doaj.org/toc/1349-4147 doi:10.1186/s41182-023-00535-7 1349-4147 https://doaj.org/article/05623df5db094a71ba95665401782fd5 |
op_doi |
https://doi.org/10.1186/s41182-023-00535-7 |
container_title |
Tropical Medicine and Health |
container_volume |
51 |
container_issue |
1 |
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1776198608617472000 |