Metabolic disorders and cardiovascular risk in people living with HIV/AIDS without the use of antiretroviral therapy
Abstract INTRODUCTION: Metabolic disorders in people living with HIV/AIDS (PLH) have been described even before the introduction of antiretroviral (ARV) drugs in the treatment of HIV infection and are risk factors for cardiovascular diseases. Based on this, the purpose of this study was to assess me...
Published in: | Revista da Sociedade Brasileira de Medicina Tropical |
---|---|
Main Authors: | , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Sociedade Brasileira de Medicina Tropical (SBMT)
|
Subjects: | |
Online Access: | https://doi.org/10.1590/0037-8682-0258-2017 https://doaj.org/article/05621ebb263948c58bf104cbc5c53443 |
id |
ftdoajarticles:oai:doaj.org/article:05621ebb263948c58bf104cbc5c53443 |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:05621ebb263948c58bf104cbc5c53443 2023-05-15T15:10:27+02:00 Metabolic disorders and cardiovascular risk in people living with HIV/AIDS without the use of antiretroviral therapy Mariana Amaral Raposo Geyza Nogueira de Almeida Armiliato Nathalia Sernizon Guimarães Camila Abrahão Caram Raíssa Domingues de Simoni Silveira Unaí Tupinambás https://doi.org/10.1590/0037-8682-0258-2017 https://doaj.org/article/05621ebb263948c58bf104cbc5c53443 EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822017000500598&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0258-2017 https://doaj.org/article/05621ebb263948c58bf104cbc5c53443 Revista da Sociedade Brasileira de Medicina Tropical, Vol 50, Iss 5, Pp 598-606 HIV/AIDS Metabolic disorders Cardiovascular risk Arctic medicine. Tropical medicine RC955-962 article ftdoajarticles https://doi.org/10.1590/0037-8682-0258-2017 2022-12-30T21:27:00Z Abstract INTRODUCTION: Metabolic disorders in people living with HIV/AIDS (PLH) have been described even before the introduction of antiretroviral (ARV) drugs in the treatment of HIV infection and are risk factors for cardiovascular diseases. Based on this, the purpose of this study was to assess metabolic disorders and cardiovascular risk in PLH before the initiation of antiretroviral treatment (ART). METHODS: This was a cross-sectional descriptive study of 87 PLH without the use of ART, which was carried out between January and September 2012 at a specialized infectious diseases center in Minas Gerais, Brazil. RESULTS: The main metabolic disorders in the population were low serum levels of HDL-cholesterol, hypertriglyceridemia and abdominal obesity. Dyslipidemia was prevalent in 62.6% of the study population, whereas metabolic syndrome (MS) was prevalent in 11.5% of patients assessed by the International Diabetes Federation (IDF) criteria and 10.8% assessed by the National Cholesterol Education Program-Adult Treatment Panel (NCEP-ATPIII) criteria. Regarding cardiovascular risk, 89.7% of the population presented a low coronary risk according to the Framingham Risk Score. A greater proportion of patients diagnosed with MS presented low cardiovascular risk (80% assessed by IDF criteria and 77.8% assessed by NCEP-ATPIII criteria). CONCLUSIONS: Metabolic disorders in this population may be due to HIV infection or lifestyle (smoking, sedentary lifestyle and inadequate diet). The introduction of ART can enhance dyslipidemia, increasing cardiovascular risk, especially among those who have classic risks of cardiovascular disease. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista da Sociedade Brasileira de Medicina Tropical 50 5 598 606 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
HIV/AIDS Metabolic disorders Cardiovascular risk Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
HIV/AIDS Metabolic disorders Cardiovascular risk Arctic medicine. Tropical medicine RC955-962 Mariana Amaral Raposo Geyza Nogueira de Almeida Armiliato Nathalia Sernizon Guimarães Camila Abrahão Caram Raíssa Domingues de Simoni Silveira Unaí Tupinambás Metabolic disorders and cardiovascular risk in people living with HIV/AIDS without the use of antiretroviral therapy |
topic_facet |
HIV/AIDS Metabolic disorders Cardiovascular risk Arctic medicine. Tropical medicine RC955-962 |
description |
Abstract INTRODUCTION: Metabolic disorders in people living with HIV/AIDS (PLH) have been described even before the introduction of antiretroviral (ARV) drugs in the treatment of HIV infection and are risk factors for cardiovascular diseases. Based on this, the purpose of this study was to assess metabolic disorders and cardiovascular risk in PLH before the initiation of antiretroviral treatment (ART). METHODS: This was a cross-sectional descriptive study of 87 PLH without the use of ART, which was carried out between January and September 2012 at a specialized infectious diseases center in Minas Gerais, Brazil. RESULTS: The main metabolic disorders in the population were low serum levels of HDL-cholesterol, hypertriglyceridemia and abdominal obesity. Dyslipidemia was prevalent in 62.6% of the study population, whereas metabolic syndrome (MS) was prevalent in 11.5% of patients assessed by the International Diabetes Federation (IDF) criteria and 10.8% assessed by the National Cholesterol Education Program-Adult Treatment Panel (NCEP-ATPIII) criteria. Regarding cardiovascular risk, 89.7% of the population presented a low coronary risk according to the Framingham Risk Score. A greater proportion of patients diagnosed with MS presented low cardiovascular risk (80% assessed by IDF criteria and 77.8% assessed by NCEP-ATPIII criteria). CONCLUSIONS: Metabolic disorders in this population may be due to HIV infection or lifestyle (smoking, sedentary lifestyle and inadequate diet). The introduction of ART can enhance dyslipidemia, increasing cardiovascular risk, especially among those who have classic risks of cardiovascular disease. |
format |
Article in Journal/Newspaper |
author |
Mariana Amaral Raposo Geyza Nogueira de Almeida Armiliato Nathalia Sernizon Guimarães Camila Abrahão Caram Raíssa Domingues de Simoni Silveira Unaí Tupinambás |
author_facet |
Mariana Amaral Raposo Geyza Nogueira de Almeida Armiliato Nathalia Sernizon Guimarães Camila Abrahão Caram Raíssa Domingues de Simoni Silveira Unaí Tupinambás |
author_sort |
Mariana Amaral Raposo |
title |
Metabolic disorders and cardiovascular risk in people living with HIV/AIDS without the use of antiretroviral therapy |
title_short |
Metabolic disorders and cardiovascular risk in people living with HIV/AIDS without the use of antiretroviral therapy |
title_full |
Metabolic disorders and cardiovascular risk in people living with HIV/AIDS without the use of antiretroviral therapy |
title_fullStr |
Metabolic disorders and cardiovascular risk in people living with HIV/AIDS without the use of antiretroviral therapy |
title_full_unstemmed |
Metabolic disorders and cardiovascular risk in people living with HIV/AIDS without the use of antiretroviral therapy |
title_sort |
metabolic disorders and cardiovascular risk in people living with hiv/aids without the use of antiretroviral therapy |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
url |
https://doi.org/10.1590/0037-8682-0258-2017 https://doaj.org/article/05621ebb263948c58bf104cbc5c53443 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 50, Iss 5, Pp 598-606 |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822017000500598&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0258-2017 https://doaj.org/article/05621ebb263948c58bf104cbc5c53443 |
op_doi |
https://doi.org/10.1590/0037-8682-0258-2017 |
container_title |
Revista da Sociedade Brasileira de Medicina Tropical |
container_volume |
50 |
container_issue |
5 |
container_start_page |
598 |
op_container_end_page |
606 |
_version_ |
1766341481623191552 |