Detection of a Yersinia pestis gene homologue in rodent samples
A homologue to a widely used genetic marker, pla, for Yersinia pestis has been identified in tissue samples of two species of rat (Rattus rattus and Rattus norvegicus) and of mice (Mus musculus and Apodemus sylvaticus) using a microarray based platform to screen for zoonotic pathogens of interest. S...
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ftdoajarticles:oai:doaj.org/article:053cc12375fb41b3b062c3d00f05865c 2024-01-07T09:46:12+01:00 Detection of a Yersinia pestis gene homologue in rodent samples Timothy A. Giles Alex D. Greenwood Kyriakos Tsangaras Tom C. Giles Paul A. Barrow Duncan Hannant Abu-Bakr Abu-Median Lisa Yon 2016-08-01T00:00:00Z https://doi.org/10.7717/peerj.2216 https://doaj.org/article/053cc12375fb41b3b062c3d00f05865c EN eng PeerJ Inc. https://peerj.com/articles/2216.pdf https://peerj.com/articles/2216/ https://doaj.org/toc/2167-8359 doi:10.7717/peerj.2216 2167-8359 https://doaj.org/article/053cc12375fb41b3b062c3d00f05865c PeerJ, Vol 4, p e2216 (2016) Yersinia pestis Rodents Screening Microarray Medicine R Biology (General) QH301-705.5 article 2016 ftdoajarticles https://doi.org/10.7717/peerj.2216 2023-12-10T01:46:56Z A homologue to a widely used genetic marker, pla, for Yersinia pestis has been identified in tissue samples of two species of rat (Rattus rattus and Rattus norvegicus) and of mice (Mus musculus and Apodemus sylvaticus) using a microarray based platform to screen for zoonotic pathogens of interest. Samples were from urban locations in the UK (Liverpool) and Canada (Vancouver). The results indicate the presence of an unknown bacterium that shares a homologue for the pla gene of Yersinia pestis, so caution should be taken when using this gene as a diagnostic marker. Article in Journal/Newspaper Rattus rattus Directory of Open Access Journals: DOAJ Articles Canada PeerJ 4 e2216 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Yersinia pestis Rodents Screening Microarray Medicine R Biology (General) QH301-705.5 |
spellingShingle |
Yersinia pestis Rodents Screening Microarray Medicine R Biology (General) QH301-705.5 Timothy A. Giles Alex D. Greenwood Kyriakos Tsangaras Tom C. Giles Paul A. Barrow Duncan Hannant Abu-Bakr Abu-Median Lisa Yon Detection of a Yersinia pestis gene homologue in rodent samples |
topic_facet |
Yersinia pestis Rodents Screening Microarray Medicine R Biology (General) QH301-705.5 |
description |
A homologue to a widely used genetic marker, pla, for Yersinia pestis has been identified in tissue samples of two species of rat (Rattus rattus and Rattus norvegicus) and of mice (Mus musculus and Apodemus sylvaticus) using a microarray based platform to screen for zoonotic pathogens of interest. Samples were from urban locations in the UK (Liverpool) and Canada (Vancouver). The results indicate the presence of an unknown bacterium that shares a homologue for the pla gene of Yersinia pestis, so caution should be taken when using this gene as a diagnostic marker. |
format |
Article in Journal/Newspaper |
author |
Timothy A. Giles Alex D. Greenwood Kyriakos Tsangaras Tom C. Giles Paul A. Barrow Duncan Hannant Abu-Bakr Abu-Median Lisa Yon |
author_facet |
Timothy A. Giles Alex D. Greenwood Kyriakos Tsangaras Tom C. Giles Paul A. Barrow Duncan Hannant Abu-Bakr Abu-Median Lisa Yon |
author_sort |
Timothy A. Giles |
title |
Detection of a Yersinia pestis gene homologue in rodent samples |
title_short |
Detection of a Yersinia pestis gene homologue in rodent samples |
title_full |
Detection of a Yersinia pestis gene homologue in rodent samples |
title_fullStr |
Detection of a Yersinia pestis gene homologue in rodent samples |
title_full_unstemmed |
Detection of a Yersinia pestis gene homologue in rodent samples |
title_sort |
detection of a yersinia pestis gene homologue in rodent samples |
publisher |
PeerJ Inc. |
publishDate |
2016 |
url |
https://doi.org/10.7717/peerj.2216 https://doaj.org/article/053cc12375fb41b3b062c3d00f05865c |
geographic |
Canada |
geographic_facet |
Canada |
genre |
Rattus rattus |
genre_facet |
Rattus rattus |
op_source |
PeerJ, Vol 4, p e2216 (2016) |
op_relation |
https://peerj.com/articles/2216.pdf https://peerj.com/articles/2216/ https://doaj.org/toc/2167-8359 doi:10.7717/peerj.2216 2167-8359 https://doaj.org/article/053cc12375fb41b3b062c3d00f05865c |
op_doi |
https://doi.org/10.7717/peerj.2216 |
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PeerJ |
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4 |
container_start_page |
e2216 |
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1787427935996608512 |