Evaluation of antifungal and antioxidant potential of two medicinal plants: Aconitum heterophyllum and Polygonum bistorta
Objective: To focus on the evaluation of antimicrobial and antioxidant activity of two endangered medicinal plants Aconitum heterophyllum (A. heterophyllum) and Polygonum bistorta (P. bistorta). Materials: Plant extracts were obtained by using microwave assisted extraction method. The in vitro antif...
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Wolters Kluwer Medknow Publications
2014
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ftdoajarticles:oai:doaj.org/article:05319cb4a09f4131a99247b8ad9fd95e 2023-05-15T15:08:54+02:00 Evaluation of antifungal and antioxidant potential of two medicinal plants: Aconitum heterophyllum and Polygonum bistorta Neelma Munir Wasqa Ijaz Imran Altaf Shagufta Naz 2014-07-01T00:00:00Z https://doi.org/10.12980/APJTB.4.201414B182 https://doaj.org/article/05319cb4a09f4131a99247b8ad9fd95e EN eng Wolters Kluwer Medknow Publications http://www.sciencedirect.com/science/article/pii/S2221169115300630 https://doaj.org/toc/2221-1691 2221-1691 doi:10.12980/APJTB.4.201414B182 https://doaj.org/article/05319cb4a09f4131a99247b8ad9fd95e Asian Pacific Journal of Tropical Biomedicine, Vol 4, Iss S2, Pp S639-S643 (2014) Medicinal plants Antifungal Antioxidant Biomedicines Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 article 2014 ftdoajarticles https://doi.org/10.12980/APJTB.4.201414B182 2022-12-31T11:51:26Z Objective: To focus on the evaluation of antimicrobial and antioxidant activity of two endangered medicinal plants Aconitum heterophyllum (A. heterophyllum) and Polygonum bistorta (P. bistorta). Materials: Plant extracts were obtained by using microwave assisted extraction method. The in vitro antifungal activity of A. heterophyllum and P. bistorta extracts were determined by measuring diameters of inhibitory zones of these extracts against Aspergillus niger and Alternalia solani. Results: Methanolic extract of A. heterophyllum showed significant (P≤0.05) antifungal activity against both the tested organisms. It was also observed that ethanolic extracts of P. bistorta also had good antifungal activity against the tested fungal strains as compared to the methanolic extracts. It showed significant antifungal activity (P≤0.05) against both the tested strains. Antioxidant activity of methanolic and ethanolic extracts of A. heterophyllum and P. bistorta were also measured using a radical scavenging method. Ascorbic acid was used as a standard. Conclusions: It was observed that A. heterophyllum and P. bistorta have significant antioxidant activity. Higher antioxidant activity was recorded in methanolic extract of A. heterophyllum as compared to its ethanolic extract. However, in case of P. bistorta ethanolic extract of the plant exhibited higher antioxidant potential than methanolic extracts. Hence both of these plants have significant antimicrobial as well as antioxidant potential. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Asian Pacific Journal of Tropical Biomedicine 4 S639 S643 |
institution |
Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Medicinal plants Antifungal Antioxidant Biomedicines Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
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Medicinal plants Antifungal Antioxidant Biomedicines Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 Neelma Munir Wasqa Ijaz Imran Altaf Shagufta Naz Evaluation of antifungal and antioxidant potential of two medicinal plants: Aconitum heterophyllum and Polygonum bistorta |
topic_facet |
Medicinal plants Antifungal Antioxidant Biomedicines Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
description |
Objective: To focus on the evaluation of antimicrobial and antioxidant activity of two endangered medicinal plants Aconitum heterophyllum (A. heterophyllum) and Polygonum bistorta (P. bistorta). Materials: Plant extracts were obtained by using microwave assisted extraction method. The in vitro antifungal activity of A. heterophyllum and P. bistorta extracts were determined by measuring diameters of inhibitory zones of these extracts against Aspergillus niger and Alternalia solani. Results: Methanolic extract of A. heterophyllum showed significant (P≤0.05) antifungal activity against both the tested organisms. It was also observed that ethanolic extracts of P. bistorta also had good antifungal activity against the tested fungal strains as compared to the methanolic extracts. It showed significant antifungal activity (P≤0.05) against both the tested strains. Antioxidant activity of methanolic and ethanolic extracts of A. heterophyllum and P. bistorta were also measured using a radical scavenging method. Ascorbic acid was used as a standard. Conclusions: It was observed that A. heterophyllum and P. bistorta have significant antioxidant activity. Higher antioxidant activity was recorded in methanolic extract of A. heterophyllum as compared to its ethanolic extract. However, in case of P. bistorta ethanolic extract of the plant exhibited higher antioxidant potential than methanolic extracts. Hence both of these plants have significant antimicrobial as well as antioxidant potential. |
format |
Article in Journal/Newspaper |
author |
Neelma Munir Wasqa Ijaz Imran Altaf Shagufta Naz |
author_facet |
Neelma Munir Wasqa Ijaz Imran Altaf Shagufta Naz |
author_sort |
Neelma Munir |
title |
Evaluation of antifungal and antioxidant potential of two medicinal plants: Aconitum heterophyllum and Polygonum bistorta |
title_short |
Evaluation of antifungal and antioxidant potential of two medicinal plants: Aconitum heterophyllum and Polygonum bistorta |
title_full |
Evaluation of antifungal and antioxidant potential of two medicinal plants: Aconitum heterophyllum and Polygonum bistorta |
title_fullStr |
Evaluation of antifungal and antioxidant potential of two medicinal plants: Aconitum heterophyllum and Polygonum bistorta |
title_full_unstemmed |
Evaluation of antifungal and antioxidant potential of two medicinal plants: Aconitum heterophyllum and Polygonum bistorta |
title_sort |
evaluation of antifungal and antioxidant potential of two medicinal plants: aconitum heterophyllum and polygonum bistorta |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2014 |
url |
https://doi.org/10.12980/APJTB.4.201414B182 https://doaj.org/article/05319cb4a09f4131a99247b8ad9fd95e |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Asian Pacific Journal of Tropical Biomedicine, Vol 4, Iss S2, Pp S639-S643 (2014) |
op_relation |
http://www.sciencedirect.com/science/article/pii/S2221169115300630 https://doaj.org/toc/2221-1691 2221-1691 doi:10.12980/APJTB.4.201414B182 https://doaj.org/article/05319cb4a09f4131a99247b8ad9fd95e |
op_doi |
https://doi.org/10.12980/APJTB.4.201414B182 |
container_title |
Asian Pacific Journal of Tropical Biomedicine |
container_volume |
4 |
container_start_page |
S639 |
op_container_end_page |
S643 |
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1766340172223348736 |