Leishmania (Leishmania) mexicana Infection in Wild Rodents from an Emergent Focus of Cutaneous Leishmaniasis in Yucatan, Mexico
In 2015, emergent cases of localized cutaneous leishmaniasis (LCL) were reported in Tinum, Yucatan, Mexico. As part of an eco-epidemiological study to characterize the elements that trigger Leishmania infection in that area, we conducted a field study to investigate the occurrence of Leishmania infe...
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2022
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ftdoajarticles:oai:doaj.org/article:052f060f4d9b457ca5754d3fb4191dbd 2023-05-15T15:09:50+02:00 Leishmania (Leishmania) mexicana Infection in Wild Rodents from an Emergent Focus of Cutaneous Leishmaniasis in Yucatan, Mexico Erika I. Sosa-Bibiano Luis A. Sánchez -Martínez Karina B. López-Ávila Juan B. Chablé-Santos Jimmy R. Torres-Castro Edith A. Fernández-Figueroa Claudia Rangel-Escareño Elsy N. Loría-Cervera 2022-01-01T00:00:00Z https://doi.org/10.1155/2022/8392005 https://doaj.org/article/052f060f4d9b457ca5754d3fb4191dbd EN eng Hindawi Limited http://dx.doi.org/10.1155/2022/8392005 https://doaj.org/toc/1687-9694 1687-9694 doi:10.1155/2022/8392005 https://doaj.org/article/052f060f4d9b457ca5754d3fb4191dbd Journal of Tropical Medicine, Vol 2022 (2022) Arctic medicine. Tropical medicine RC955-962 article 2022 ftdoajarticles https://doi.org/10.1155/2022/8392005 2022-12-31T02:45:23Z In 2015, emergent cases of localized cutaneous leishmaniasis (LCL) were reported in Tinum, Yucatan, Mexico. As part of an eco-epidemiological study to characterize the elements that trigger Leishmania infection in that area, we conducted a field study to investigate the occurrence of Leishmania infection in wild rodents. From November 2019 to February 2020, rodents were caught from three sites located in the municipality of Tinum, Yucatan. For each specimen, clinical signs suggestive of Leishmania infection were recorded. Samples from the tail, liver, and spleen were taken for the identification of Leishmania DNA by PCR. Twenty rodents belonging to two species were caught including Heteromys gaumeri (55%, 11/20) and Ototylomys phyllotis (45%, 9/20). Fifty-five percent of the animals presented white spots on the tail, 15% had splenomegaly, and 5% had hepatomegaly. Fifty-five percent (11/20) of the animals were found infected by Leishmania. Heteromys gaumeri was caught in all trapping sites and was the most infected species (63.6%, 7/11). The percentage of infection for O. phyllotis was 44.4% (4/9). Leishmania (Leishmania) mexicana was identified as the infecting species in two H. gaumeri. This study provides, for the first time, evidence of Leishmania infection in wild rodents from the Yucatan state. Heteromys gaumeri and O. phyllotis may be involved in the transmission cycle of L. mexicana in this emergent focus; however, further longitudinal studies are needed to confirm their role as primary reservoirs. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Journal of Tropical Medicine 2022 1 7 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
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English |
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Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Erika I. Sosa-Bibiano Luis A. Sánchez -Martínez Karina B. López-Ávila Juan B. Chablé-Santos Jimmy R. Torres-Castro Edith A. Fernández-Figueroa Claudia Rangel-Escareño Elsy N. Loría-Cervera Leishmania (Leishmania) mexicana Infection in Wild Rodents from an Emergent Focus of Cutaneous Leishmaniasis in Yucatan, Mexico |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 |
description |
In 2015, emergent cases of localized cutaneous leishmaniasis (LCL) were reported in Tinum, Yucatan, Mexico. As part of an eco-epidemiological study to characterize the elements that trigger Leishmania infection in that area, we conducted a field study to investigate the occurrence of Leishmania infection in wild rodents. From November 2019 to February 2020, rodents were caught from three sites located in the municipality of Tinum, Yucatan. For each specimen, clinical signs suggestive of Leishmania infection were recorded. Samples from the tail, liver, and spleen were taken for the identification of Leishmania DNA by PCR. Twenty rodents belonging to two species were caught including Heteromys gaumeri (55%, 11/20) and Ototylomys phyllotis (45%, 9/20). Fifty-five percent of the animals presented white spots on the tail, 15% had splenomegaly, and 5% had hepatomegaly. Fifty-five percent (11/20) of the animals were found infected by Leishmania. Heteromys gaumeri was caught in all trapping sites and was the most infected species (63.6%, 7/11). The percentage of infection for O. phyllotis was 44.4% (4/9). Leishmania (Leishmania) mexicana was identified as the infecting species in two H. gaumeri. This study provides, for the first time, evidence of Leishmania infection in wild rodents from the Yucatan state. Heteromys gaumeri and O. phyllotis may be involved in the transmission cycle of L. mexicana in this emergent focus; however, further longitudinal studies are needed to confirm their role as primary reservoirs. |
format |
Article in Journal/Newspaper |
author |
Erika I. Sosa-Bibiano Luis A. Sánchez -Martínez Karina B. López-Ávila Juan B. Chablé-Santos Jimmy R. Torres-Castro Edith A. Fernández-Figueroa Claudia Rangel-Escareño Elsy N. Loría-Cervera |
author_facet |
Erika I. Sosa-Bibiano Luis A. Sánchez -Martínez Karina B. López-Ávila Juan B. Chablé-Santos Jimmy R. Torres-Castro Edith A. Fernández-Figueroa Claudia Rangel-Escareño Elsy N. Loría-Cervera |
author_sort |
Erika I. Sosa-Bibiano |
title |
Leishmania (Leishmania) mexicana Infection in Wild Rodents from an Emergent Focus of Cutaneous Leishmaniasis in Yucatan, Mexico |
title_short |
Leishmania (Leishmania) mexicana Infection in Wild Rodents from an Emergent Focus of Cutaneous Leishmaniasis in Yucatan, Mexico |
title_full |
Leishmania (Leishmania) mexicana Infection in Wild Rodents from an Emergent Focus of Cutaneous Leishmaniasis in Yucatan, Mexico |
title_fullStr |
Leishmania (Leishmania) mexicana Infection in Wild Rodents from an Emergent Focus of Cutaneous Leishmaniasis in Yucatan, Mexico |
title_full_unstemmed |
Leishmania (Leishmania) mexicana Infection in Wild Rodents from an Emergent Focus of Cutaneous Leishmaniasis in Yucatan, Mexico |
title_sort |
leishmania (leishmania) mexicana infection in wild rodents from an emergent focus of cutaneous leishmaniasis in yucatan, mexico |
publisher |
Hindawi Limited |
publishDate |
2022 |
url |
https://doi.org/10.1155/2022/8392005 https://doaj.org/article/052f060f4d9b457ca5754d3fb4191dbd |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Journal of Tropical Medicine, Vol 2022 (2022) |
op_relation |
http://dx.doi.org/10.1155/2022/8392005 https://doaj.org/toc/1687-9694 1687-9694 doi:10.1155/2022/8392005 https://doaj.org/article/052f060f4d9b457ca5754d3fb4191dbd |
op_doi |
https://doi.org/10.1155/2022/8392005 |
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Journal of Tropical Medicine |
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2022 |
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1 |
op_container_end_page |
7 |
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1766340937205678080 |