Analysis of the prevalence of dyslipidemia in individuals with HIV and its association with antiretroviral therapy
Introduction Antiretroviral therapy (ART) has been used to treat large numbers of patients living with human immunodeficiency virus (HIV) infection. Lipid disorders are often observed in these patients, and include elevations in total cholesterol (TC) and triglycerides (TG). Methods A cross-sectiona...
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ftdoajarticles:oai:doaj.org/article:052bdc1f55af4eb7be2ab293b42e8d81 2023-05-15T15:08:52+02:00 Analysis of the prevalence of dyslipidemia in individuals with HIV and its association with antiretroviral therapy Talita Gabriela de Limas Gustavo de Araujo Pinto Liz Miriane Marcato Daniel Reszel Coelho 2014-10-01T00:00:00Z https://doi.org/10.1590/0037-8682-0128-2014 https://doaj.org/article/052bdc1f55af4eb7be2ab293b42e8d81 EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822014000500547&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0128-2014 https://doaj.org/article/052bdc1f55af4eb7be2ab293b42e8d81 Revista da Sociedade Brasileira de Medicina Tropical, Vol 47, Iss 5, Pp 547-551 (2014) Antiretroviral therapy HIV Dyslipidemia AIDS Arctic medicine. Tropical medicine RC955-962 article 2014 ftdoajarticles https://doi.org/10.1590/0037-8682-0128-2014 2022-12-30T23:08:11Z Introduction Antiretroviral therapy (ART) has been used to treat large numbers of patients living with human immunodeficiency virus (HIV) infection. Lipid disorders are often observed in these patients, and include elevations in total cholesterol (TC) and triglycerides (TG). Methods A cross-sectional study was performed using 333 patient records from the Regional Hospital of São José Doutor Homero de Miranda Gomes (HRSJHMG). The study population consisted of patients with HIV who were under medical follow up, either on or off drug treatment. The data were entered into Excel and exported to SPSS 16.0 for analysis using chi-square testing. We used prevalence ratios as the measure of association. Results Lipid abnormalities were observed in 78.9% of individuals who received ART. Of the 308 subjects on ART, 59.1%, 41.9%, and 33.1% had TG, TC and low-density lipoprotein (LDL) abnormalities, respectively. The prevalence of LDL changes was 2.57-fold higher in individuals who had been using ART for more than 12 months, compared to those using ART for 6 to 12 months. Conclusions HIV patients showed a significant increase in the association between TC and TG levels and the use of ART. In particular, changes in TC, LDL and TG were greater in individuals who had received ART for over more than 12 months. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista da Sociedade Brasileira de Medicina Tropical 47 5 547 551 |
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Directory of Open Access Journals: DOAJ Articles |
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Antiretroviral therapy HIV Dyslipidemia AIDS Arctic medicine. Tropical medicine RC955-962 |
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Antiretroviral therapy HIV Dyslipidemia AIDS Arctic medicine. Tropical medicine RC955-962 Talita Gabriela de Limas Gustavo de Araujo Pinto Liz Miriane Marcato Daniel Reszel Coelho Analysis of the prevalence of dyslipidemia in individuals with HIV and its association with antiretroviral therapy |
topic_facet |
Antiretroviral therapy HIV Dyslipidemia AIDS Arctic medicine. Tropical medicine RC955-962 |
description |
Introduction Antiretroviral therapy (ART) has been used to treat large numbers of patients living with human immunodeficiency virus (HIV) infection. Lipid disorders are often observed in these patients, and include elevations in total cholesterol (TC) and triglycerides (TG). Methods A cross-sectional study was performed using 333 patient records from the Regional Hospital of São José Doutor Homero de Miranda Gomes (HRSJHMG). The study population consisted of patients with HIV who were under medical follow up, either on or off drug treatment. The data were entered into Excel and exported to SPSS 16.0 for analysis using chi-square testing. We used prevalence ratios as the measure of association. Results Lipid abnormalities were observed in 78.9% of individuals who received ART. Of the 308 subjects on ART, 59.1%, 41.9%, and 33.1% had TG, TC and low-density lipoprotein (LDL) abnormalities, respectively. The prevalence of LDL changes was 2.57-fold higher in individuals who had been using ART for more than 12 months, compared to those using ART for 6 to 12 months. Conclusions HIV patients showed a significant increase in the association between TC and TG levels and the use of ART. In particular, changes in TC, LDL and TG were greater in individuals who had received ART for over more than 12 months. |
format |
Article in Journal/Newspaper |
author |
Talita Gabriela de Limas Gustavo de Araujo Pinto Liz Miriane Marcato Daniel Reszel Coelho |
author_facet |
Talita Gabriela de Limas Gustavo de Araujo Pinto Liz Miriane Marcato Daniel Reszel Coelho |
author_sort |
Talita Gabriela de Limas |
title |
Analysis of the prevalence of dyslipidemia in individuals with HIV and its association with antiretroviral therapy |
title_short |
Analysis of the prevalence of dyslipidemia in individuals with HIV and its association with antiretroviral therapy |
title_full |
Analysis of the prevalence of dyslipidemia in individuals with HIV and its association with antiretroviral therapy |
title_fullStr |
Analysis of the prevalence of dyslipidemia in individuals with HIV and its association with antiretroviral therapy |
title_full_unstemmed |
Analysis of the prevalence of dyslipidemia in individuals with HIV and its association with antiretroviral therapy |
title_sort |
analysis of the prevalence of dyslipidemia in individuals with hiv and its association with antiretroviral therapy |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
2014 |
url |
https://doi.org/10.1590/0037-8682-0128-2014 https://doaj.org/article/052bdc1f55af4eb7be2ab293b42e8d81 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 47, Iss 5, Pp 547-551 (2014) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822014000500547&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0128-2014 https://doaj.org/article/052bdc1f55af4eb7be2ab293b42e8d81 |
op_doi |
https://doi.org/10.1590/0037-8682-0128-2014 |
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Revista da Sociedade Brasileira de Medicina Tropical |
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47 |
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