Epidemiological features, echocardiographic findings, and parasite load in patients with Chagas disease
Abstract INTRODUCTION Chagas disease is a major public health problem that is endemic in Brazil and Latin America. This study aimed to determine the socioeconomic, demographic, and clinical characteristics of 171 patients (mean age, 45 years; female, 65%) with Chagas disease at Hospital Universitári...
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ftdoajarticles:oai:doaj.org/article:04cb5d2b1f1a4a378abafc3e931e31d0 2023-05-15T15:07:06+02:00 Epidemiological features, echocardiographic findings, and parasite load in patients with Chagas disease Hilda Maria Benevides da Silva de Arruda Marcelle Araújo Ribeiro Antonia Marilene da Silva Daniel Vasconcelos Maria Regina Fernandes de Oliveira Elza Ferreira Noronha 2019-12-01T00:00:00Z https://doi.org/10.1590/0037-8682-0541-2018 https://doaj.org/article/04cb5d2b1f1a4a378abafc3e931e31d0 EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100344&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0541-2018 https://doaj.org/article/04cb5d2b1f1a4a378abafc3e931e31d0 Revista da Sociedade Brasileira de Medicina Tropical, Vol 52 (2019) Epidemiological profile University hospital Chagas disease Arctic medicine. Tropical medicine RC955-962 article 2019 ftdoajarticles https://doi.org/10.1590/0037-8682-0541-2018 2022-12-31T02:52:39Z Abstract INTRODUCTION Chagas disease is a major public health problem that is endemic in Brazil and Latin America. This study aimed to determine the socioeconomic, demographic, and clinical characteristics of 171 patients (mean age, 45 years; female, 65%) with Chagas disease at Hospital Universitário de Brasília, Federal District, Brazil. METHODS We implemented this cross-sectional study using a clinical epidemiological questionnaire, electrocardiography, echocardiography, and quantitative detection of Trypanosoma cruzi DNA in blood using qRT-PCR. RESULTS Among the patients, 26.3% had a full elementary education, and 13.2% were illiterate. Most (63.6%) were economically classified as class C, and 51.5% were born in Bahia state. A total of 62.0% participants reported previous contact with the triatomine bug. The clinical forms of the disease were indeterminate (69.51%), cardiac (15.24%), digestive (10.37%), and mixed (4.88%). The most common electrocardiographic abnormality was complete right bundle branch block in association with a divisional anterosuperior block. Only 14.6% of the patients complied with benznidazole medication for at least 60 days, and 164 of them were assessed by echocardiography. The parasite load was positive in 56% of the patients. CONCLUSIONS: Chagas disease affected mostly women, with the indeterminate chronic form of the disease. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista da Sociedade Brasileira de Medicina Tropical 52 |
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Directory of Open Access Journals: DOAJ Articles |
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Epidemiological profile University hospital Chagas disease Arctic medicine. Tropical medicine RC955-962 |
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Epidemiological profile University hospital Chagas disease Arctic medicine. Tropical medicine RC955-962 Hilda Maria Benevides da Silva de Arruda Marcelle Araújo Ribeiro Antonia Marilene da Silva Daniel Vasconcelos Maria Regina Fernandes de Oliveira Elza Ferreira Noronha Epidemiological features, echocardiographic findings, and parasite load in patients with Chagas disease |
topic_facet |
Epidemiological profile University hospital Chagas disease Arctic medicine. Tropical medicine RC955-962 |
description |
Abstract INTRODUCTION Chagas disease is a major public health problem that is endemic in Brazil and Latin America. This study aimed to determine the socioeconomic, demographic, and clinical characteristics of 171 patients (mean age, 45 years; female, 65%) with Chagas disease at Hospital Universitário de Brasília, Federal District, Brazil. METHODS We implemented this cross-sectional study using a clinical epidemiological questionnaire, electrocardiography, echocardiography, and quantitative detection of Trypanosoma cruzi DNA in blood using qRT-PCR. RESULTS Among the patients, 26.3% had a full elementary education, and 13.2% were illiterate. Most (63.6%) were economically classified as class C, and 51.5% were born in Bahia state. A total of 62.0% participants reported previous contact with the triatomine bug. The clinical forms of the disease were indeterminate (69.51%), cardiac (15.24%), digestive (10.37%), and mixed (4.88%). The most common electrocardiographic abnormality was complete right bundle branch block in association with a divisional anterosuperior block. Only 14.6% of the patients complied with benznidazole medication for at least 60 days, and 164 of them were assessed by echocardiography. The parasite load was positive in 56% of the patients. CONCLUSIONS: Chagas disease affected mostly women, with the indeterminate chronic form of the disease. |
format |
Article in Journal/Newspaper |
author |
Hilda Maria Benevides da Silva de Arruda Marcelle Araújo Ribeiro Antonia Marilene da Silva Daniel Vasconcelos Maria Regina Fernandes de Oliveira Elza Ferreira Noronha |
author_facet |
Hilda Maria Benevides da Silva de Arruda Marcelle Araújo Ribeiro Antonia Marilene da Silva Daniel Vasconcelos Maria Regina Fernandes de Oliveira Elza Ferreira Noronha |
author_sort |
Hilda Maria Benevides da Silva de Arruda |
title |
Epidemiological features, echocardiographic findings, and parasite load in patients with Chagas disease |
title_short |
Epidemiological features, echocardiographic findings, and parasite load in patients with Chagas disease |
title_full |
Epidemiological features, echocardiographic findings, and parasite load in patients with Chagas disease |
title_fullStr |
Epidemiological features, echocardiographic findings, and parasite load in patients with Chagas disease |
title_full_unstemmed |
Epidemiological features, echocardiographic findings, and parasite load in patients with Chagas disease |
title_sort |
epidemiological features, echocardiographic findings, and parasite load in patients with chagas disease |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
2019 |
url |
https://doi.org/10.1590/0037-8682-0541-2018 https://doaj.org/article/04cb5d2b1f1a4a378abafc3e931e31d0 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 52 (2019) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100344&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0541-2018 https://doaj.org/article/04cb5d2b1f1a4a378abafc3e931e31d0 |
op_doi |
https://doi.org/10.1590/0037-8682-0541-2018 |
container_title |
Revista da Sociedade Brasileira de Medicina Tropical |
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52 |
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